Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells
Research
RF Safe Research Library
Nov 7, 2023
This in vitro study characterized spinning oscillating magnetic field (sOMF) stimulation patterns that the authors report can induce cytotoxicity in two types of human glioma cells. The reported effect was linked to a critical rise in superoxide, and was reversed by the antioxidant Trolox, suggesting ROS involvement.…
Effects of prenatal mobile phone radiation exposure on MMP9 expression: Implications for inflammation, oxidative stress, and sensory-motor impairment after neonatal hypoxia- ischemia in rats
Research
RF Safe Research Library
Oct 13, 2023
This animal study examined whether prenatal mobile phone RF exposure affects brain injury markers and outcomes after neonatal hypoxia-ischemia in rats. The HI/Exposure group showed higher MMP-9 expression along with increased inflammatory and oxidative stress markers, larger infarct volume and edema, and worse…
Lipoic acid inhibits cognitive impairment induced by multiple cell phones in young male rats: role of Sirt1 and Atg7 pathway.
Research
RF Safe Research Library
Jan 1, 2023
This animal study examined whether lipoic acid modifies cognitive and hippocampal effects in young male rats exposed to EMF emitted from multiple cell phones. The authors report improved learning performance but impaired long-term memory consolidation after EMF exposure, alongside changes in hippocampal…
Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue.
Research
RF Safe Research Library
Jan 1, 2023
This experimental mouse study tested whether N-acetylcysteine (NAC), pulsed electromagnetic fields (PEMF), or their combination improves outcomes after transplantation of vitrified ovarian tissue. The abstract reports increased follicle numbers and enhanced vascularization in NAC, PEMF, and NAC+PEMF groups, along…
Ameliorative effects of crocin against electromagnetic field-induced oxidative stress and liver and kidney injuries in mice.
Research
RF Safe Research Library
Jan 1, 2023
This mouse experiment evaluated whether crocin (50 mg/kg) mitigates liver and kidney injury associated with 2100 MHz electromagnetic field exposure. EMF exposure was associated with increased serum markers of kidney and liver injury, reduced antioxidant enzyme activity, and histopathological/ultrastructural changes…
Electromagnetic fields ameliorate hepatic lipid accumulation and oxidative stress: potential role of CaMKKβ/AMPK/SREBP-1c and Nrf2 pathways.
Research
RF Safe Research Library
Jan 1, 2023
This animal study examined EMF exposure in a mouse high-fat diet model of NAFLD. The authors report that EMF exposure reduced hepatic lipid accumulation and markers of oxidative stress, alongside changes consistent with activation of CaMKKβ/AMPK and Nrf2-related signaling. The abstract concludes EMF could be a…
Bidirectional Effect of Repeated Exposure to Extremely Low-Frequency Electromagnetic Field (50 Hz) of 1 and 7 mT on Oxidative/Antioxidative Status in Rat's Brain: The Prediction for the Vulnerability to Diseases.
Research
RF Safe Research Library
Jan 1, 2022
This rat study examined repeated 50 Hz ELF-EMF exposure (1 or 7 mT) and measured oxidative stress and antioxidant defense markers in the prefrontal cortex, including responses to a subsequent open-field stressor. The authors report intensity- and repetition-dependent effects: 1 mT produced weak changes and was…
Cardiac Cell Exposure to Electromagnetic Fields: Focus on Oxdative Stress and Apoptosis.
Research
RF Safe Research Library
Jan 1, 2022
This study assessed whether 915 MHz RF-EMF exposure alters oxidative stress and apoptosis markers in cardiac cells and mouse heart tissue. The authors report no statistically significant differences in apoptotic profile, antioxidant capacity, tissue integrity, or expression of apoptosis/antioxidant genes after…
Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study evaluated short-term extremely low frequency electromagnetic field (ELF-EMF) exposure and silver nanoparticles (AgNPs), alone and combined, for antibacterial effects and apoptosis induction in MCF-7 breast cancer cells. The authors report time-dependent reductions in bacterial viable counts, with…
Prioritizing health outcomes when assessing the effects of exposure to radiofrequency electromagnetic fields: A survey among experts.
Research
RF Safe Research Library
Jan 1, 2021
This paper reports a survey designed to prioritize which RF EMF-related health outcomes should be addressed in systematic reviews. Of 300 experts queried, 164 responded and rated cancer, heat-related effects, adverse birth/pregnancy outcomes, electromagnetic hypersensitivity, cognitive impairment, and oxidative…
The guardians of germ cells; Sertoli-derived exosomes against electromagnetic field-induced oxidative stress in mouse spermatogonial stem cells.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed mouse spermatogonial stem cells to 50 Hz EMF (2.5 mT; 1 h/day for 5 days) and assessed oxidative stress and cell health outcomes. The authors report increased ROS and apoptosis with reduced antioxidant (catalase) expression, viability, and colonization after EMF exposure. Sertoli…
Evaluation of the neuroprotective effects of Vitamin E on the rat substantia nigra neural cells exposed to electromagnetic field: An ultrastructural study.
Research
RF Safe Research Library
Jan 1, 2021
This rat study exposed animals to a 50 Hz, 3 mT electromagnetic field and assessed oxidative stress markers and substantia nigra ultrastructure. EMF exposure was associated with higher lipid peroxidation (MDA), lower SOD activity, and TEM-detected changes in nucleus/nuclear membrane and myelin sheath. Vitamin E…
Assessment of function, histopathological changes, and oxidative stress in liver tissue due to ionizing and non-ionizing radiations.
Research
RF Safe Research Library
Jan 1, 2020
This animal study evaluated liver function, histopathology, and oxidative stress markers after exposure to RF-EMF (900/1800 MHz and 2.4 GHz), x-rays (10 cGy or 8 Gy), and combinations including RF-EMF pre-exposure. Some liver enzymes (AST, ALT, ALP) showed some association with irradiation, while…
Effects of pulse-modulated radiofrequency magnetic field (RF-EMF) exposure on apoptosis, autophagy, oxidative stress and electron chain transport function in human neuroblastoma and murine microglial cells.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study exposed murine microglial (N9) and human neuroblastoma (SH-SY5Y) cells to ELF-modulated 935 MHz RF-EMF at 4 W/kg for 2 or 24 hours. The authors report no changes in apoptosis, cell viability, or AIF across conditions. They report increased ATG5 after 24 hours and a transient glutathione increase…
Antimicrobial activity of rosemary leaf extracts and efficacy of ethanol extract against testicular damage caused by 50-Hz electromagnetic field in albino rats.
Research
RF Safe Research Library
Jan 1, 2020
This animal study exposed male albino rats to a 50 Hz electromagnetic field for 2 or 4 hours and assessed reproductive hormones, oxidative stress markers, and testicular histology after 30 days. The abstract reports that EMF exposure reduced serum FSH, testosterone, and LH and catalase activity, while increasing…
Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice.
Research
RF Safe Research Library
Jan 1, 2018
This animal study exposed 14-month-old C57BL/6 mice to 1950 MHz RF-EMF (SAR 5 W/kg) for 8 months. The authors report that aging was associated with increased oxidative damage, DNA damage, apoptosis, and glial activation markers in brain tissue. Long-term RF-EMF exposure did not change these markers in aged mice and…
Extremely low frequency electromagnetic field reduces oxidative stress during the rehabilitation of post-acute stroke patients.
Research
RF Safe Research Library
Jan 1, 2018
This study evaluated ELF-EMF magnetotherapy as an adjunct to post-acute ischemic stroke rehabilitation in 57 patients, comparing those who received ELF-EMF therapy with those who did not. The authors report that oxidative stress markers (TBARS, thiol, and carbonyl groups) decreased more in the ELF-EMF group than in…
Electromagnetic field exposure (50 Hz) impairs response to noxious heat in American cockroach.
Research
RF Safe Research Library
Jan 1, 2018
This animal study examined whether 50 Hz electromagnetic field exposure (7 mT) affects heat-escape behavior and oxidative balance in American cockroaches. The authors report increased latency to escape from noxious heat after 24 h, 72 h, and 7 days of exposure. Biomarkers suggested oxidative stress, with elevated…
Selenium supplementation ameliorates electromagnetic field-induced oxidative stress in the HEK293 cells.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study examined whether selenium supplementation modifies oxidative stress and apoptosis markers in HEK293 cells exposed to 2.4 GHz EMF. The authors report that EMF exposure increased lipid peroxidation (MDA) and apoptosis-related markers while decreasing antioxidant enzyme activities and bcl-2 versus…
Continuous 900-megahertz electromagnetic field applied in middle and late-adolescence causes qualitative and quantitative changes in the ovarian morphology, tissue and blood biochemistry of the rat.
Research
RF Safe Research Library
Jan 1, 2018
This animal study exposed adolescent female rats to a 900-MHz electromagnetic field for 1 hour per day from postnatal days 35 to 59 and assessed ovarian histology and biochemical markers. The EMF group showed multiple histopathological changes in ovarian tissue and had fewer secondary follicles than the other groups.…
Effect of 2.45 GHz microwave radiation on the fertility pattern in male mice.
Research
RF Safe Research Library
Jan 1, 2018
This animal study examined 2.45 GHz microwave exposure in male Swiss albino mice for 2 hours per day over 30 days. The authors report increased oxidative stress markers and reduced antioxidant enzymes and testosterone in exposed mice versus sham controls. They also report micronuclei formation in blood and…
Oxidative and mutagenic effects of low intensity GSM 1800 MHz microwave radiation
Research
RF Safe Research Library
Jan 1, 2018
This animal study used developing quail embryos to assess oxidative and mutagenic effects of low-intensity GSM 1800 MHz radiation from a commercial smartphone. The authors report statistically significant increases in oxidative stress markers, DNA integrity damage, and oxidative DNA damage (8-oxo-dG) in exposed…
The beneficial effect of ginsenosides extracted by pulsed electric field against hydrogen peroxide-induced oxidative stress in HEK-293 cells.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study compared ginsenosides extracted using pulsed electric field (PEF) versus solvent cold soak extraction (SCSE). The abstract reports that PEF extracts had higher antioxidant capacity and provided greater protection against hydrogen peroxide-induced oxidative stress in HEK-293 cells, including…
Lasting hepatotoxic effects of prenatal mobile phone exposure.
Research
RF Safe Research Library
Jan 1, 2017
This animal study examined liver outcomes in rat offspring 60 days after prenatal exposure to a 900 MHz electromagnetic field for 24 hours/day during gestation. The exposed group showed biochemical changes consistent with oxidative stress (higher MDA, lower GSH) and elevated liver enzymes (ALT, AST). Histopathology…
Effect of extremely low-frequency electromagnetic fields on antioxidant activity in the human keratinocyte cell line NCTC 2544.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed human keratinocyte cells (NCTC 2544) to 50 Hz ELF-EMF at 0.25–2 G and assessed oxidative stress-related endpoints. Significant increases in ROS were reported at 0.5 and 1 G, with associated short-term changes in antioxidant and lipid peroxidation markers. The authors report that…