Selenium supplementation ameliorates electromagnetic field-induced oxidative stress in the HEK293 cells.
This in vitro study examined whether selenium supplementation modifies oxidative stress and apoptosis markers in HEK293 cells exposed to 2.4 GHz EMF. The authors report that EMF exposure increased lipid peroxidation (MDA) and apoptosis-related markers while decreasing antioxidant enzyme activities and bcl-2 versus control. Selenium pre-treatment (100 or 200 nM) was reported to partially reverse these changes compared with EMF alone.
Key points
- The study used HEK293 cells exposed to 2.4 GHz EMF for 1 hour.
- EMF exposure was associated with higher MDA and lower SOD and GSH-Px activities versus control.
- EMF exposure was associated with higher apoptosis and caspase-3 and lower bcl-2 versus control.
- Selenium (100 or 200 nM) was added for 48 hours before EMF exposure in the intervention groups.
- Selenium plus EMF groups showed lower MDA and higher SOD and GSH-Px than EMF alone.
- Selenium plus EMF groups showed lower apoptosis and caspase-3 and higher bcl-2 than EMF alone.
Referenced studies & papers
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AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
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