Assessment of function, histopathological changes, and oxidative stress in liver tissue due to ionizing and non-ionizing radiations.
This animal study evaluated liver function, histopathology, and oxidative stress markers after exposure to RF-EMF (900/1800 MHz and 2.4 GHz), x-rays (10 cGy or 8 Gy), and combinations including RF-EMF pre-exposure. Some liver enzymes (AST, ALT, ALP) showed some association with irradiation, while gamma-glutamyltransferase did not. Oxidative stress markers (MDA and PCO) increased after 8 Gy, and RF-EMF pre-exposure was reported to modulate these changes, which the authors interpret as possibly involving oxidative stress in an adaptive response.
Key points
- The study used 120 Wistar rats randomized into 10 groups (12 per group).
- Exposures included RF-EMF at 900/1800 MHz and 2.4 GHz, x-rays at 10 cGy and 8 Gy, and combined protocols including RF-EMF pre-exposure.
- AST, ALT, and ALP showed some association with irradiation, while gamma-glutamyltransferase was not associated.
- MDA and protein carbonyl increased after 8 Gy x-ray exposure.
- Pre-exposure to RF-EMF was reported to modulate changes in MDA and protein carbonyl after 8 Gy.
- Lobular inflammation frequency differed by intervention type.
- The authors suggest oxidative stress may be involved in an adaptive response to combined ionizing and non-ionizing exposures.
Referenced studies & papers
Relevant papers in OpenMel
Source:
Open original
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
Comments
Log in to comment.
No comments yet.