Inflammasome Activation and IL-1β Release Triggered by Nanosecond Pulsed Electric Fields in Murine Innate Immune Cells and Skin
200-ns pulsed electric fields induced ASC aggregation, caspase-1 activation, and IL-1β release in multiple murine innate immune cell types and in vivo in mouse skin. Potassium efflux was partially responsible for inflammasome activation, and experiments with …