Investigation of the Effects of 2.45 GHz Near-Field EMF on Yeast

PAPER manual Antioxidants (Basel) 2025 Animal study Effect: harm Evidence: Low

Read original paper → DOI: 10.3390/antiox14070820 Evidence Lab

Abstract

Category: Cellular Biology Tags: EMF, 2.45 GHz, yeast, oxidative stress, DNA damage, microwave radiation, membrane permeability DOI: 10.3390/antiox14070820 URL: mdpi.com Overview This study addresses the critical health and safety concerns regarding the pervasive exposure to 2.45 GHz electromagnetic fields (EMF), particularly as a result of widespread everyday technologies such as mobile devices. Experimental Design - Yeast suspensions were exposed to 2.45 GHz microwave radiation at two distances (2 cm and 4 cm) from the antenna. - Exposure durations were set at 20 and 60 minutes. - Endpoints included UV-absorbing substance release (membrane permeabilization), total intracellular antioxidant activity, reduced glutathione levels, and DNA damage (via comet assay). Findings - A significant correlation was observed between reduced antioxidant activity and increased membrane permeability after 20 minutes of exposure at a 2 cm distance, indicating oxidative stress induced by EMF exposure. - This oxidative stress effect was not replicated through conventional heating, suggesting a specific EMF-related mechanism. - Irradiation for 60 minutes at 4 cm caused a mild increase in membrane permeability; this did not align with a change in cellular antioxidant status. - Both test conditions of EMF exposure showed a trend towards increased DNA damage in yeast cells. Conclusion The research demonstrates clear biological effects of near-field 2.45 GHz EMF exposure on yeast, specifically membrane permeabilization, oxidative stress, and DNA damage. These findings establish a link between EMF exposure and potential health risks, supporting the need for further investigation and caution in the everyday application of such frequencies.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Yeast suspensions

Sample size

—

Exposure

microwave other · 2450 MHz · 20 and 60 minutes

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

Yeast exposed to 2.45 GHz near-field microwave radiation showed an association between reduced antioxidant activity and increased membrane permeability after 20 minutes at 2 cm, consistent with oxidative stress; this was not reproduced by conventional heating. A 60-minute exposure at 4 cm produced a mild increase in membrane permeability without a corresponding change in antioxidant status, and both exposure conditions showed a trend toward increased DNA damage.

Outcomes measured

Membrane permeability (UV-absorbing substance release)
Total intracellular antioxidant activity
Reduced glutathione levels
DNA damage (comet assay)

Limitations

Sample size not reported in provided abstract/metadata
Dosimetry metrics (e.g., SAR, power density) not reported in provided abstract/metadata
Only yeast model; generalizability to humans not addressed in provided abstract/metadata
DNA damage described as a trend; statistical significance not specified in provided abstract/metadata

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": "other",
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": "20 and 60 minutes"
    },
    "population": "Yeast suspensions",
    "sample_size": null,
    "outcomes": [
        "Membrane permeability (UV-absorbing substance release)",
        "Total intracellular antioxidant activity",
        "Reduced glutathione levels",
        "DNA damage (comet assay)"
    ],
    "main_findings": "Yeast exposed to 2.45 GHz near-field microwave radiation showed an association between reduced antioxidant activity and increased membrane permeability after 20 minutes at 2 cm, consistent with oxidative stress; this was not reproduced by conventional heating. A 60-minute exposure at 4 cm produced a mild increase in membrane permeability without a corresponding change in antioxidant status, and both exposure conditions showed a trend toward increased DNA damage.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in provided abstract/metadata",
        "Dosimetry metrics (e.g., SAR, power density) not reported in provided abstract/metadata",
        "Only yeast model; generalizability to humans not addressed in provided abstract/metadata",
        "DNA damage described as a trend; statistical significance not specified in provided abstract/metadata"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "2.45 GHz",
        "microwave radiation",
        "near-field",
        "yeast",
        "oxidative stress",
        "antioxidant activity",
        "glutathione",
        "membrane permeability",
        "DNA damage",
        "comet assay"
    ],
    "suggested_hubs": []
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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