Radiofrequency radiation-induced gene expression

Key points

• The paper describes gene expression as an adaptive cellular response and reports that RFR exposure has been associated with altered gene expression in many studies.
• Genes discussed as affected include those involved in stress response, oxidative processes, apoptosis, DNA damage detection/repair, protein repair, and neural function regulation.
• The authors interpret the gene expression literature as supporting RFR being a cellular stressor linked to oxidative changes and damage-related pathways.
• The abstract states that gene expression effects have been observed at or below 0.4 W/kg SAR, a level referenced in major guidelines.
• It reports that over 200 studies have described biological effects below 0.4 W/kg SAR, which the authors say challenges current regulatory models.
• The review notes variability across studies, stating that not all studies observe significant effects.
• Future research priorities highlighted include mechanisms of cellular stress (including neuroendocrine pathways) and systematic study of oxidative/free-radical processes and modulation effects.

Referenced studies & papers

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