Radiofrequency radiation-induced gene expression
Research
RF Safe Research Library
Jan 1, 2025
This review summarizes studies reporting radiofrequency radiation (RFR)-associated changes in gene expression across biological systems. Reported affected genes relate to cellular stress responses, oxidative processes, apoptosis, DNA damage detection/repair, protein repair, and neural function regulation. The authors…
Altered development in rodent brain cells after 900 MHz radiofrequency exposure
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RF Safe Research Library
Jan 1, 2025
This animal and in vitro study examined non-thermal 900 MHz RF-EMF exposure during prenatal and postnatal development at 0.08 and 0.4 W/kg SAR. The authors report changes consistent with altered neurodevelopment, including reduced BDNF, reduced in vivo cell proliferation, and disrupted synaptic balance in rat pup…
Proteomic Characterization of Human Peripheral Blood Mononuclear Cells Exposed to a 50 Hz Magnetic Field
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RF Safe Research Library
Jan 1, 2025
This in vitro study compared proteomic profiles of PBMCs from three human donors after 24-hour exposure to a 50 Hz, 1 mT extremely low-frequency magnetic field versus unexposed cells. The abstract reports broad protein expression changes, including upregulation of proteins associated with metabolic processes and…
It is the Frequency that Matters: Effects of Electromagnetic Fields on the Release and Content of Extracellular Vesicles.
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RF Safe Research Library
Jan 1, 2023
This preprint describes an in vitro bioreactor-based system to test whether electromagnetic/electrical stimulation affects extracellular vesicles (EVs). Using proteomics and single-vesicle flow cytometry, the authors report that stimulation at physiological current amplitudes can modulate EV content in a…
Lipidomic alteration and stress-defense mechanism of soil nematode Caenorhabditis elegans in response to extremely low-frequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2019
This animal (nematode) study exposed Caenorhabditis elegans to 50 Hz, 3 mT extremely low-frequency EMF and assessed multi-omics responses. The authors report significant lipidomic, proteomic, and transcriptomic alterations, including increased triacylglycerols. Pathway analyses suggest disrupted lipid metabolism,…
Treatment of Common Sunflower (Helianthus annus L.) Seeds with Radio-frequency Electromagnetic Field and Cold Plasma Induces Changes in Seed Phytohormone Balance, Seedling Development and Leaf Protein Expression.
Research
RF Safe Research Library
Jan 1, 2019
This study assessed pre-sowing sunflower seed treatments using vacuum, 5.28 MHz radio-frequency cold plasma, and an electromagnetic field for varying durations. The authors report faster germination with cold plasma (7 min) and EMF (15 min), while germination percentage was mostly unchanged except for a decrease…
Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study used proteome-wide semi-quantitative mass spectrometry to assess molecular changes after short-term exposure to ELF (50 Hz), UMTS (2.1 GHz), and WiFi (5.8 GHz) in human and mouse cell types. The authors report that fewer than 1% of quantified proteins changed slightly in abundance and that…
Unraveling the effects of static magnetic field stress on cytosolic proteins of Salmonella by using a proteomic approach.
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study examined how Salmonella enterica serovar Hadar adapts to a 200 mT static magnetic field for 9 hours using proteomics. The authors report 35 cytosolic proteins with >2-fold expression changes after exposure, spanning metabolism, oxidative stress response, energy homeostasis, translation elongation,…
Effect of ELF-EMF Exposure on Human Neuroblastoma Cell Line: a Proteomics Analysis
Research
RF Safe Research Library
Jan 1, 2014
This in vitro study exposed SH-SY5Y human neuroblastoma cells to a 2 mT, 50 Hz magnetic field for 3 hours and assessed protein expression using proteomics. The authors report that 189 proteins changed expression in exposed cells compared with controls, with PCA/clustering separating samples by condition. They…