Evaluation of the Thyroids of Offsprings Exposed to 2450 MHz Radiofrequency Radiation During Pregnancy: A Sixth Month Data
Abstract
Category: Epidemiology Tags: radiofrequency radiation, 2450 MHz, prenatal exposure, thyroid, Wi-Fi, rats, histopathology URL: jidmr.com M24_3112_Suleyman_DASDAG_Turkey-Exp-2.pdf Overview This study aimed to determine whether exposure to radiofrequency radiation (RFR) emitted by wireless internet providers (2450 MHz) throughout the day during rats' pregnancy causes alterations in the thyroid tissues of their offspring. Methodology - Pregnant rats in the experimental group were exposed to 2450 MHz RFR (24 hours/day, pulse wave mode, 1 W output strength, simulating Wi-Fi waves). - Offspring (n = 8 per group) were randomly selected from both control and experimental groups. - At the end of the sixth month, thyroid tissues were collected for histopathological and biochemical evaluations. - Statistical analysis was performed using Mann-Whitney U-tests and T-tests. Statistical significance was set at p < 0.05. Findings - There was a significant difference in mononuclear cell infiltration (p=0.03) and vascular increase (congestion) (p<0.001) between groups. - No significant differences were observed for TUNEL-positive cell percentage (p=0.62) and H2A.X antibody levels (p=0.68) between control and experimental groups. Conclusion Exposure to 2450 MHz radiofrequency radiation during the prenatal period caused some changes, specifically an increase in mononuclear cell infiltration and vascular congestion in the thyroid tissue of rat offspring, indicating possible tissue-level effects. However, there were no statistically significant differences in TUNEL-positive cell percentage and H2A.X levels. This research adds to the body of evidence linking electromagnetic field exposure to potential biological effects, even if not all markers reached statistical significance.
AI evidence extraction
Main findings
In rat offspring assessed at 6 months, prenatal 2450 MHz RFR exposure was associated with higher mononuclear cell infiltration and increased vascular congestion in thyroid tissue compared with controls. No statistically significant differences were reported for TUNEL-positive cell percentage or H2A.X antibody levels between groups.
Outcomes measured
- Thyroid histopathology (mononuclear cell infiltration)
- Thyroid histopathology (vascular increase/congestion)
- TUNEL-positive cell percentage
- H2A.X antibody levels
Limitations
- Animal study; generalizability to humans is uncertain
- Small group size (n=8 per group)
- Exposure described by output strength (1 W) without reported SAR or dosimetry details in the abstract
- Outcomes limited to selected histopathological and biochemical markers at a single time point (6 months)
Suggested hubs
-
wifi
(0.9) Exposure described as 2450 MHz RFR simulating Wi‑Fi waves.
View raw extracted JSON
{
"publication_year": 2024,
"study_type": "animal",
"exposure": {
"band": "RF",
"source": "Wi-Fi",
"frequency_mhz": 2450,
"sar_wkg": null,
"duration": "Prenatal exposure during pregnancy; 24 hours/day (pulse wave mode)"
},
"population": "Rat offspring from pregnant rats exposed during pregnancy",
"sample_size": 16,
"outcomes": [
"Thyroid histopathology (mononuclear cell infiltration)",
"Thyroid histopathology (vascular increase/congestion)",
"TUNEL-positive cell percentage",
"H2A.X antibody levels"
],
"main_findings": "In rat offspring assessed at 6 months, prenatal 2450 MHz RFR exposure was associated with higher mononuclear cell infiltration and increased vascular congestion in thyroid tissue compared with controls. No statistically significant differences were reported for TUNEL-positive cell percentage or H2A.X antibody levels between groups.",
"effect_direction": "mixed",
"limitations": [
"Animal study; generalizability to humans is uncertain",
"Small group size (n=8 per group)",
"Exposure described by output strength (1 W) without reported SAR or dosimetry details in the abstract",
"Outcomes limited to selected histopathological and biochemical markers at a single time point (6 months)"
],
"evidence_strength": "low",
"confidence": 0.7800000000000000266453525910037569701671600341796875,
"peer_reviewed_likely": "yes",
"stance": "concern",
"stance_confidence": 0.6999999999999999555910790149937383830547332763671875,
"summary": "This animal study examined whether continuous prenatal exposure to 2450 MHz radiofrequency radiation (simulating Wi‑Fi) affects thyroid tissue in rat offspring at 6 months. The exposed group showed significantly increased mononuclear cell infiltration and vascular congestion in thyroid histology. TUNEL-positive cell percentage and H2A.X antibody levels did not differ significantly between groups.",
"key_points": [
"Pregnant rats were exposed to 2450 MHz RFR in pulse wave mode for 24 hours/day during pregnancy.",
"Offspring thyroids were evaluated at the end of the sixth month using histopathological and biochemical measures.",
"Mononuclear cell infiltration and vascular congestion were significantly higher in the exposed group than controls.",
"TUNEL-positive cell percentage did not show a statistically significant difference between groups.",
"H2A.X antibody levels did not show a statistically significant difference between groups.",
"The findings indicate some tissue-level thyroid changes after prenatal RFR exposure, with other damage markers not differing in this study."
],
"categories": [
"Animal Studies",
"Wi-Fi",
"Prenatal Exposure",
"Thyroid"
],
"tags": [
"Radiofrequency Radiation",
"2450 MHz",
"Wi-Fi",
"Prenatal Exposure",
"Pregnancy",
"Rat Offspring",
"Thyroid",
"Histopathology",
"Mononuclear Cell Infiltration",
"Vascular Congestion",
"TUNEL Assay",
"H2A.X"
],
"keywords": [
"radiofrequency radiation",
"2450 MHz",
"prenatal exposure",
"thyroid",
"Wi-Fi",
"rats",
"histopathology"
],
"suggested_hubs": [
{
"slug": "wifi",
"weight": 0.90000000000000002220446049250313080847263336181640625,
"reason": "Exposure described as 2450 MHz RFR simulating Wi‑Fi waves."
}
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"social": {
"tweet": "Rat study: prenatal 2450 MHz (Wi‑Fi-like) RF exposure was linked to increased thyroid mononuclear cell infiltration and vascular congestion at 6 months, while TUNEL and H2A.X markers did not differ significantly.",
"facebook": "In a rat study, continuous prenatal exposure to 2450 MHz radiofrequency radiation (simulating Wi‑Fi) was associated with increased mononuclear cell infiltration and vascular congestion in offspring thyroid tissue at 6 months, while TUNEL-positive cells and H2A.X levels were not significantly different.",
"linkedin": "Animal study (2024): prenatal 2450 MHz (Wi‑Fi-like) RF exposure in rats was associated with increased mononuclear cell infiltration and vascular congestion in offspring thyroid tissue at 6 months; TUNEL and H2A.X measures showed no significant differences."
}
}
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