The effect of a rotating magnetic field on the antioxidant system in healthy volunteers - preliminary
Abstract
The effect of a rotating magnetic field on the antioxidant system in healthy volunteers - preliminary study Cecerska-Heryć E, Gliźniewicz M, Grygorcewicz B, Serwin N, Stodolak P, Słodzińska W, Birger R, Goszka M, Polikowska A, Budkowska M, Rakoczy R, Dołęgowska B. The effect of a rotating magnetic field on the antioxidant system in healthy volunteers - preliminary study. Sci Rep. 2024 Apr 15;14(1):8677. doi: 10.1038/s41598-024-59391-y. Abstract Oxidative stress is characterized by an excessive concentration of reactive oxygen species (ROS) resulting from a disturbance in the balance between ROS production and their removal by antioxidant systems (SOD, CAT, GPx). Prolonged and intense oxidative stress can cause various forms of damage to cells, which markers are total antioxidant capacity (TAC), reactive oxygen species modulator (ROMO1), and malondialdehyde (MDA). It has been demonstrated that magnetic fields can positively affect human health, for example, by reducing oxidative stress. Determination of the effect of a rotating magnetic field (RMF) on the activity/concentration of selected oxidative stress markers. A group of 30 healthy volunteers (15 women and 15 men) (mean age 24.8 ± 5.1) in the study classified into the following groups: internal control group (CG);1 h 25 Hz (samples placed in the field for one hour at 25 Hz); 3 h 25 Hz (samples placed in the field for 3 h at 25 Hz), the 1 h 50 Hz group ( placed in RMF for an hour at 50 Hz), and a group of 3 h 50 Hz (samples placed in the field for 3 h at 50 Hz). Serum samples were collected in K2EDTA tubes.. The magnetic induction value obtained for RMF is 37.06 mT and 42.64 mT. Activity/concentration of selected oxidative stress markers was analyzed by ELISA. The influence of an RMF on the activity/concentration of SOD, MDA, TAC, and ROMO1 was demonstrated (p < 0.001; p = 0.0013; p < 0.001; p = 0.003). The RFM can reduce oxidative stress, as evidenced by higher SOD and CAT activities in the CG than in samples placed in the RFM. Prolonged exposure to the RFM at 50 Hz increased the TAC level, indicating an intensification of oxidative stress in these samples. The optimal conditions for staying in the RFM (reducing oxidative stress) are 1 h 50 Hz for SOD and MDA; 3 h 25 Hz for CAT and TAC. In the case of ROMO1, it is stated that 1 h 25 Hz are the optimal conditions for no increased production of ROS. Open access paper: nature.com
AI evidence extraction
Main findings
In serum samples from 30 healthy volunteers, exposure to a rotating magnetic field (25 Hz or 50 Hz for 1 h or 3 h; magnetic induction 37.06 mT and 42.64 mT) was reported to influence oxidative stress markers (SOD, MDA, TAC, ROMO1) with statistically significant differences. The abstract states RMF may reduce oxidative stress under some conditions, but also reports that prolonged exposure at 50 Hz increased TAC, interpreted as intensified oxidative stress in those samples.
Outcomes measured
- Superoxide dismutase (SOD) activity/concentration
- Catalase (CAT) activity/concentration
- Glutathione peroxidase (GPx) (mentioned as antioxidant system component)
- Total antioxidant capacity (TAC)
- Reactive oxygen species modulator 1 (ROMO1)
- Malondialdehyde (MDA)
Limitations
- Preliminary study
- Exposure appears to be applied to collected serum samples rather than whole-body human exposure (ex vivo design implied)
- No details in abstract on randomization/blinding or baseline comparability across conditions
- Limited exposure conditions (only 25 Hz/50 Hz and 1 h/3 h)
View raw extracted JSON
{
"publication_year": 2024,
"study_type": "other",
"exposure": {
"band": "ELF",
"source": "rotating magnetic field (RMF) exposure of serum samples",
"frequency_mhz": null,
"sar_wkg": null,
"duration": "1 h or 3 h at 25 Hz or 50 Hz"
},
"population": "Healthy volunteers (serum samples)",
"sample_size": 30,
"outcomes": [
"Superoxide dismutase (SOD) activity/concentration",
"Catalase (CAT) activity/concentration",
"Glutathione peroxidase (GPx) (mentioned as antioxidant system component)",
"Total antioxidant capacity (TAC)",
"Reactive oxygen species modulator 1 (ROMO1)",
"Malondialdehyde (MDA)"
],
"main_findings": "In serum samples from 30 healthy volunteers, exposure to a rotating magnetic field (25 Hz or 50 Hz for 1 h or 3 h; magnetic induction 37.06 mT and 42.64 mT) was reported to influence oxidative stress markers (SOD, MDA, TAC, ROMO1) with statistically significant differences. The abstract states RMF may reduce oxidative stress under some conditions, but also reports that prolonged exposure at 50 Hz increased TAC, interpreted as intensified oxidative stress in those samples.",
"effect_direction": "mixed",
"limitations": [
"Preliminary study",
"Exposure appears to be applied to collected serum samples rather than whole-body human exposure (ex vivo design implied)",
"No details in abstract on randomization/blinding or baseline comparability across conditions",
"Limited exposure conditions (only 25 Hz/50 Hz and 1 h/3 h)"
],
"evidence_strength": "low",
"confidence": 0.7399999999999999911182158029987476766109466552734375,
"peer_reviewed_likely": "yes",
"stance": "neutral",
"stance_confidence": 0.66000000000000003108624468950438313186168670654296875,
"summary": "This preliminary study examined whether a rotating magnetic field (25 Hz or 50 Hz; 1 h or 3 h) affects oxidative stress markers measured by ELISA in serum samples from 30 healthy volunteers. The abstract reports significant changes in several markers (including SOD, MDA, TAC, and ROMO1) across exposure conditions. It describes both potentially reduced oxidative stress under some conditions and increased TAC after prolonged 50 Hz exposure, interpreted as intensified oxidative stress.",
"key_points": [
"Thirty healthy volunteers provided serum samples that were placed in a rotating magnetic field under different frequency and duration conditions.",
"The reported magnetic induction values for the RMF were 37.06 mT and 42.64 mT.",
"The abstract reports statistically significant influences of RMF on SOD, MDA, TAC, and ROMO1.",
"The authors describe some exposure conditions as reducing oxidative stress and others (prolonged 50 Hz) as increasing TAC, interpreted as intensified oxidative stress.",
"The abstract proposes “optimal” RMF conditions for different biomarkers (e.g., 1 h 50 Hz for SOD and MDA; 3 h 25 Hz for CAT and TAC).",
"The work is described as preliminary and appears to assess effects in serum samples rather than direct in vivo exposure outcomes."
],
"categories": [
"ELF Magnetic Fields",
"Human Studies",
"Oxidative Stress",
"Biomarkers"
],
"tags": [
"Rotating Magnetic Field",
"Extremely Low Frequency",
"Healthy Volunteers",
"Serum Samples",
"Oxidative Stress",
"Antioxidant Enzymes",
"Superoxide Dismutase",
"Catalase",
"Total Antioxidant Capacity",
"Malondialdehyde",
"ROMO1",
"ELISA"
],
"keywords": [
"rotating magnetic field",
"RMF",
"25 Hz",
"50 Hz",
"magnetic induction",
"oxidative stress",
"ROS",
"SOD",
"CAT",
"TAC",
"ROMO1",
"MDA"
],
"suggested_hubs": [],
"social": {
"tweet": "Preliminary Sci Rep (2024): serum samples from 30 healthy volunteers exposed to a rotating magnetic field (25/50 Hz; 1–3 h) showed significant changes in oxidative stress markers (e.g., SOD, MDA, TAC, ROMO1), with mixed patterns across conditions.",
"facebook": "A preliminary 2024 Scientific Reports study tested rotating magnetic field exposure (25/50 Hz; 1–3 hours) on serum samples from 30 healthy volunteers and reported significant changes in several oxidative stress markers, with both potentially reduced and increased oxidative stress depending on conditions.",
"linkedin": "Scientific Reports (2024) preliminary study: serum samples from 30 healthy volunteers were exposed to a rotating magnetic field (25/50 Hz; 1–3 h; ~37–43 mT). The abstract reports significant changes in oxidative stress biomarkers (SOD, MDA, TAC, ROMO1) with mixed effects depending on exposure conditions."
}
}
AI can be wrong. Always verify against the paper.
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