Generational Risk of Colon and Rectal Cancer in Recent Birth Cohorts under Age 40 - the Hypothetical Role of Radiofrequency Radiation from Cell Phones
Abstract
Generational Risk of Colon and Rectal Cancer in Recent Birth Cohorts under Age 40 - the Hypothetical Role of Radiofrequency Radiation from Cell Phones Devra L Davis, Aaron M. Pilarcik, Anthony B. Miller. Generational Risk of Colon and Rectal Cancer in Recent Birth Cohorts under Age 40 - the Hypothetical Role of Radiofrequency Radiation from Cell Phones. Ann Gastroenterol Dig Dis, 3(1): 09-16. 2020. Abstract To determine if there are shifts in patterns of cancer, rates of disease can be evaluated in terms of Generational Risk (GR), comparing those born recently with those born decades earlier. Using data from the U.S. Centers for Disease Control and Prevention (CDC), the U.S. Surveillance Epidemiology and End-Results (SEER) Program and Iranian cancer registries, increases in GR of colon and rectal cancer in those under age 50 are presented. For the U.S. those born in the 1990s have a doubled risk of colon cancer (GR=2) and a fourfold increase in rectal cancer (GR=4) by the time they reach age 24 compared to those born six decades ago. Experimental studies have determined that the colon and rectum of Sprague-Dawley rats are exquisitely sensitive to both ionizing and non- ionizing radiofrequency radiation (RFR), expressing significant differences in patterns of methylation of a number of well-identified proteins and other biomarkers predictive of cancer risk. Modeling of nonionizing exposures also indicates that absorption of RFR into the colon and rectum from cell phones stored in the pocket exceeds current test limits by up to 5-fold. French government tests of phones positioned next to the body report exposures to non-ionizing radiation that are up to 11 times more than current guidelines. Based on these findings, it is prudent to develop policies to reduce direct exposures to RFR from cell phones, as occurs when they are kept next to the body, and to promote advances in hardware and software that reduce direct exposures to RFR. Open access paper: somatopublications.com cancer-in-recent-birth-cohorts-under-age-40-the-hypothetical-role-of-radiofrequency-radiation-from-cell- phones.pdf
AI evidence extraction
Main findings
The paper presents increases in generational risk of colon and rectal cancer in younger birth cohorts using U.S. and Iranian registry data, reporting higher generational risk for those born in the 1990s compared with those born decades earlier. It discusses experimental and modeling evidence suggesting potential sensitivity of colon/rectum to radiofrequency radiation and higher near-body exposures from phones carried in pockets, and argues for policies to reduce direct body exposure from cell phones.
Outcomes measured
- Colon cancer incidence (generational risk)
- Rectal cancer incidence (generational risk)
- Biomarkers/methylation patterns in colon/rectum (animal experimental studies, referenced)
- Modeled RF absorption into colon/rectum from phones in pocket (referenced)
- Phone compliance testing results near-body (French government tests, referenced)
Limitations
- Study described as evaluating generational risk patterns and proposing a hypothetical role of radiofrequency radiation; causality is not established in the abstract.
- No sample sizes, statistical methods, or uncertainty measures are provided in the abstract.
- Relies on multiple lines of evidence (registry trends, animal experiments, modeling, and government phone tests) without details on how they were systematically selected or synthesized.
- Exposure characterization (frequency, duration, and individual-level exposure) is not described in the abstract.
Suggested hubs
-
cell-phones
(0.95) Focuses on radiofrequency radiation from cell phones and near-body exposure when phones are kept in pockets.
View raw extracted JSON
{
"publication_year": 2020,
"study_type": "review",
"exposure": {
"band": "RF",
"source": "mobile phone",
"frequency_mhz": null,
"sar_wkg": null,
"duration": null
},
"population": "People under age 50 (generational risk comparisons using U.S. CDC/SEER data and Iranian cancer registries); also references Sprague-Dawley rats in experimental studies",
"sample_size": null,
"outcomes": [
"Colon cancer incidence (generational risk)",
"Rectal cancer incidence (generational risk)",
"Biomarkers/methylation patterns in colon/rectum (animal experimental studies, referenced)",
"Modeled RF absorption into colon/rectum from phones in pocket (referenced)",
"Phone compliance testing results near-body (French government tests, referenced)"
],
"main_findings": "The paper presents increases in generational risk of colon and rectal cancer in younger birth cohorts using U.S. and Iranian registry data, reporting higher generational risk for those born in the 1990s compared with those born decades earlier. It discusses experimental and modeling evidence suggesting potential sensitivity of colon/rectum to radiofrequency radiation and higher near-body exposures from phones carried in pockets, and argues for policies to reduce direct body exposure from cell phones.",
"effect_direction": "harm",
"limitations": [
"Study described as evaluating generational risk patterns and proposing a hypothetical role of radiofrequency radiation; causality is not established in the abstract.",
"No sample sizes, statistical methods, or uncertainty measures are provided in the abstract.",
"Relies on multiple lines of evidence (registry trends, animal experiments, modeling, and government phone tests) without details on how they were systematically selected or synthesized.",
"Exposure characterization (frequency, duration, and individual-level exposure) is not described in the abstract."
],
"evidence_strength": "low",
"confidence": 0.66000000000000003108624468950438313186168670654296875,
"peer_reviewed_likely": "unknown",
"stance": "concern",
"stance_confidence": 0.7800000000000000266453525910037569701671600341796875,
"summary": "This review discusses rising generational risk of colon and rectal cancer in people under age 50 using U.S. CDC/SEER data and Iranian cancer registries, highlighting higher risks in more recent birth cohorts. It proposes a hypothetical contribution from radiofrequency radiation (RFR) from cell phones, citing referenced animal experiments, exposure modeling for phones carried in pockets, and near-body phone testing reports. The authors conclude that policies to reduce direct body exposure to RFR from phones are prudent.",
"key_points": [
"Uses registry data (CDC/SEER and Iranian registries) to describe increased generational risk of colon and rectal cancer in younger cohorts.",
"Reports that U.S. individuals born in the 1990s have higher generational risk for colon and rectal cancer by age 24 compared with those born six decades earlier.",
"Cites experimental studies in Sprague-Dawley rats reporting biomarker/methylation differences in colon and rectum after radiofrequency radiation exposure.",
"References modeling suggesting RFR absorption into colon/rectum from phones stored in pockets may exceed current test limits.",
"References French government testing reporting higher near-body phone exposures than current guidelines.",
"Frames the role of cell-phone RFR as hypothetical and calls for exposure-reduction policies and technology changes."
],
"categories": [
"Cancer",
"Epidemiology",
"Mobile Phones",
"RF Exposure Assessment",
"Policy"
],
"tags": [
"Colon Cancer",
"Rectal Cancer",
"Early-Onset Cancer",
"Generational Risk",
"Cancer Registries",
"SEER",
"CDC Data",
"Radiofrequency Radiation",
"Mobile Phones",
"Pocket Carrying",
"Near-Body Testing",
"SAR Compliance Testing",
"Exposure Modeling",
"Methylation Biomarkers",
"Precautionary Policy"
],
"keywords": [
"colon cancer",
"rectal cancer",
"generational risk",
"birth cohorts",
"radiofrequency radiation",
"cell phones",
"SEER",
"CDC",
"Iranian cancer registries",
"Sprague-Dawley rats",
"methylation",
"absorption modeling"
],
"suggested_hubs": [
{
"slug": "cell-phones",
"weight": 0.9499999999999999555910790149937383830547332763671875,
"reason": "Focuses on radiofrequency radiation from cell phones and near-body exposure when phones are kept in pockets."
}
],
"social": {
"tweet": "Review links rising early-onset colon/rectal cancer generational risk trends with a hypothetical role for cell-phone RF exposure, citing registry data, animal biomarker findings, and near-body exposure modeling; calls for reducing direct body exposure.",
"facebook": "A review reports increased generational risk of colon and rectal cancer in younger cohorts and discusses a hypothetical contribution from radiofrequency radiation from cell phones, referencing registry trends, animal biomarker studies, and near-body exposure assessments; it argues for policies to reduce direct body exposure.",
"linkedin": "This review examines generational risk patterns for early-onset colon and rectal cancer using U.S. and Iranian registry data and discusses a hypothetical role of cell-phone radiofrequency radiation, citing referenced animal, modeling, and near-body testing evidence, and recommending exposure-reduction policies."
}
}
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