Archive

12 posts

Filters: tag: wistar-rats Clear

Ameliorative Role of Coenzyme Q10 in RF Radiation-Associated Testicular and Oxidative Impairments in a 3.5-GHz Exposure Model

Research PubMed: RF-EMF health Jan 24, 2026

A rat study in Bioelectromagnetics examined GSM-modulated 3.5 GHz RF-EMF exposure (2 h/day for 30 days) and reported adverse changes in male reproductive hormones, oxidative stress markers, and testicular histology. The authors also tested Coenzyme Q10 (CoQ10) and found it partially ameliorated some RF-associated alterations. The paper notes that because the exposure used a GSM-modulated waveform, findings cannot be extrapolated to FR1 5G NR signals, and calls for further research under real-world conditions.

Ameliorative Role of Coenzyme Q10 in RF Radiation-Associated Testicular and Oxidative Impairments in a 3.5-GHz Exposure Model

Research RF Safe Research Library Jan 1, 2026

This animal experiment assessed GSM-modulated 3.5 GHz RF exposure in male Wistar rats and reported hormonal, oxidative, and histological changes consistent with testicular impairment. RF exposure was associated with lower testosterone, LH, and FSH, higher oxidative stress (increased MDA and TOS), and degenerative testicular histology. Coenzyme Q10 supplementation partially mitigated several reported changes. The authors caution against generalizing these results to FR1 5G NR signals and call for further research.

Synergistic Effects of 2600 MHz Radiofrequency Exposure and Indomethacin on Oxidative Stress and Gastric Mucosal Injury in Rats

Research RF Safe Research Library Jan 1, 2025

This rat study tested whether 2600 MHz radiofrequency field exposure interacts with indomethacin to affect gastric tissue. Both exposures alone were reported to increase oxidative stress and reduce antioxidant markers in the stomach. Co-exposure was reported to intensify oxidative stress, apoptosis, and histological gastric mucosal injury compared with either factor alone, consistent with a synergistic detrimental effect in this model.

Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats

Research RF Safe Research Library Jan 1, 2025

This randomized controlled animal study examined chronic 35.5 GHz millimeter wave exposure in male Wistar rats (2 hours/day for 60 days) compared with control and sham groups. The exposed group showed reduced sperm count and viability along with testicular histopathological changes. Oxidative stress markers shifted toward increased lipid peroxidation and reduced antioxidant defenses, and comet assay results indicated increased DNA damage.

Histomorphometric study of thyroid tissue in juvenile rats exposed to 5G electromagnetic fields

Research RF Safe Research Library Jan 1, 2025

This animal study examined thyroid histomorphometry in juvenile male Wistar rats after 2 weeks of 5G EMF exposure (3.5 GHz, 1.5 V/m). Exposed rats showed larger follicle and colloid areas and a significantly lower Thyroid Activation Index, which the authors interpret as thyroid hypoactivity. The authors suggest this may represent a potential health risk and call for further work including hormone assays and mechanistic studies.

Protective effects of quercetin against 3.5 GHz RF radiation-induced thyroid dysfunction and oxidative stress in rats

Research RF Safe Research Library Jan 1, 2025

This rat study examined repeated 3.5 GHz RF exposure (2 hours/day, 5 days/week for 30 days) and thyroid-related outcomes, with and without quercetin. The abstract reports altered thyroid hormones (lower T3/T4, higher TSH) and increased oxidative stress in thyroid tissue after RF exposure. Quercetin appeared partially protective, though effects were not uniformly statistically significant, and SAR simulations indicated relatively higher absorption in the thyroid region.

Effect of short-term extremely low-frequency electromagnetic field on respiratory functions

Research RF Safe Research Library Jan 1, 2025

This animal study tested whether short-term ELF-EMF exposure alters respiratory physiology in rats. Twenty Wistar albino rats were assigned to control or EMF exposure (50 Hz, 0.3 mT for 2 minutes) with respiratory parameters measured before, during, and after exposure. The study reports changes during exposure (lower respiratory rate and higher cycle duration, inspiration time, and tidal volume) but no differences after exposure, and it frames the findings as relevant to EMF safety and potential health risks.

5G Radiofrequency Exposure Reduces PRDM16 and C/EBP � mRNA Expression, Two Key Biomarkers for Brown Adipogenesis

Research RF Safe Research Library Jan 1, 2025

This animal study exposed juvenile and young adult Wistar rats to 5G (3.5 GHz) or 2G (900 MHz) radiofrequency fields (1.5 V/m) for 1–2 weeks and measured brown adipose tissue-related gene expression by RT-qPCR. The abstract reports significant downregulation of PRDM16 and C/EBP mRNA after 5G exposure, while UCP1-dependent thermogenesis markers were not significantly changed at the transcriptional level. The authors interpret these findings as a potential partial disruption of brown adipocyte differentiation and raise EMF safety concerns, while calling for further confirmatory research.

Experimental Study of Animal Behavior under the Influence of the Electromagnetic Field of the 5G Mobile Communication Standard

Research RF Safe Research Library Jan 1, 2024

This pilot animal study exposed mature male Wistar rats to 4.9 GHz electromagnetic fields described as 5G-standard, for 15 days (2 hours/day) in a semi-anechoic shielded chamber. Open-field testing found no clear behavioral differences between unmodulated and modulated exposures. Statistically significant behavioral changes occurred in both exposed and control animals, which the authors attribute to changes in the environmental electromagnetic background, making causal interpretation uncertain.

Effect of Repeated Exposure to Complexly Organized Electromagnetic Radiation on the Rat Behavior in the "Open Field" Test

Research RF Safe Research Library Jan 1, 2024

This animal study examined repeated pulsed-modulated RF exposure (1–4 GHz; total pulse power density 300 μW/cm2) in male and female Wistar rats and assessed behavior using the open field test. The abstract reports stress reactions and long-term memory impairment in some rats, with females described as more sensitive than males. Reported effects were transient, with behavior returning to baseline within 1.5–2 months after exposure stopped. The authors suggest potential concern for constant exposure scenarios, though this is not directly evaluated in humans here.

Mitigating Heat-Induced Sperm Damage and Testicular Tissue Abnormalities: The Protective Role of Radiofrequency Radiation from Wi-Fi Routers in Rodent Models

Research RF Safe Research Library Jan 1, 2024

This rodent study examined whether 2.45 GHz Wi‑Fi router RF-EMF exposure could mitigate heat-stress-related reproductive damage in male rats. The combined RF-EMF + heat group reportedly had improved testicular structure measures and sperm quality versus heat-only, while RF-EMF alone was also reported to alter testis and sperm parameters. The authors interpret the findings as potentially consistent with an adaptive response and call for more research on mechanisms and safety.

Effects of radiofrequency radiation exposure on blood-brain barrier permeability in male and female rats

Research RF Safe Research Library Jan 1, 2011

This rat study tested whether acute exposure to 0.9 and 1.8 GHz continuous-wave radiofrequency radiation alters blood-brain barrier permeability. Using Evans-blue/albumin as a tracer, the authors report no BBB leakage in exposed female rats but a significant increase in albumin in exposed male rat brains versus sham. The authors interpret this as suggesting BBB/vascular permeability changes in males at SAR levels stated to be below international limits.

Page 1 / 1