[The pathogenesis of central nervous system functional disordersafter exposure to microwave radiation].

PAPER pubmed Voprosy meditsinskoi khimii 1992 Animal study Effect: harm Evidence: Low

Read original paper → PMID: 1329345 Evidence Lab

Abstract

A rate of lipid peroxidation, content of biogenic amines and cyclic nucleotides were studied in various brain structures of 168 rats under conditions of microwave irradiation within 24 min at 46 mW/cm2. Total irradiation of animals was shown to result in distinct inhibition of monoaminergic activity of brain, especially of hypothalamus, in impairment of metabolic reactions, in exhaustion of the lipid antioxidative system of brain cortex and in stimulation of the contrainsular apparatus functions.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Rats

Sample size

168

Exposure

microwave · 24 min

Evidence strength

Low

Confidence: 72% · Peer-reviewed: yes

Main findings

In 168 rats exposed to total-body microwave irradiation for 24 minutes at 46 mW/cm2, the authors report inhibition of monoaminergic activity in the brain (especially hypothalamus), impairment of metabolic reactions, exhaustion of the lipid antioxidative system in the brain cortex, and stimulation of contrainsular apparatus functions.

Outcomes measured

Lipid peroxidation rate in brain structures
Biogenic amines content in brain structures
Cyclic nucleotides content in brain structures
Monoaminergic activity (especially hypothalamus)
Metabolic reactions in brain
Lipid antioxidative system status in brain cortex
Contrainsular apparatus functions

Limitations

Frequency not reported
SAR not reported
No control/sham conditions described in the abstract
Outcome measures and statistical details not provided in the abstract
Exposure characterization limited to power density and duration

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": "24 min"
    },
    "population": "Rats",
    "sample_size": 168,
    "outcomes": [
        "Lipid peroxidation rate in brain structures",
        "Biogenic amines content in brain structures",
        "Cyclic nucleotides content in brain structures",
        "Monoaminergic activity (especially hypothalamus)",
        "Metabolic reactions in brain",
        "Lipid antioxidative system status in brain cortex",
        "Contrainsular apparatus functions"
    ],
    "main_findings": "In 168 rats exposed to total-body microwave irradiation for 24 minutes at 46 mW/cm2, the authors report inhibition of monoaminergic activity in the brain (especially hypothalamus), impairment of metabolic reactions, exhaustion of the lipid antioxidative system in the brain cortex, and stimulation of contrainsular apparatus functions.",
    "effect_direction": "harm",
    "limitations": [
        "Frequency not reported",
        "SAR not reported",
        "No control/sham conditions described in the abstract",
        "Outcome measures and statistical details not provided in the abstract",
        "Exposure characterization limited to power density and duration"
    ],
    "evidence_strength": "low",
    "confidence": 0.7199999999999999733546474089962430298328399658203125,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave irradiation",
        "rats",
        "brain structures",
        "lipid peroxidation",
        "biogenic amines",
        "cyclic nucleotides",
        "monoaminergic activity",
        "hypothalamus",
        "oxidative stress",
        "antioxidative system"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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