Microwave radiation: a useful fixation method for viral vaccine quantitation.

PAPER pubmed Journal of virological methods 1991 Other Effect: unclear Evidence: Insufficient

Read original paper → DOI: 10.1016/0166-0934(91)90044-z PMID: 1874912 Evidence Lab

Abstract

As an alternative to the formalin fixation of cells before staining, microwave irradiation was found a very advantageous fixation procedure in viral vaccine quantitation assays. The use of microwaves allows to avoid dangerous chemicals and thereby reduces time and equipment.

AI evidence extraction

At a glance

Study type

Other

Effect direction

unclear

Population

—

Sample size

—

Exposure

microwave laboratory equipment

Evidence strength

Insufficient

Confidence: 66% · Peer-reviewed: yes

Main findings

Microwave irradiation was reported as an advantageous alternative to formalin fixation of cells before staining in viral vaccine quantitation assays, allowing avoidance of dangerous chemicals and reducing time and equipment.

Outcomes measured

cell fixation method performance in viral vaccine quantitation assays
use of formalin vs microwave irradiation for fixation
time/equipment/chemical use in assay workflow

Limitations

No exposure parameters (frequency, power, duration) reported in abstract
No quantitative results or performance metrics reported in abstract
Study design and sample size not described in abstract

View raw extracted JSON

{
    "study_type": "other",
    "exposure": {
        "band": "microwave",
        "source": "laboratory equipment",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": null,
    "sample_size": null,
    "outcomes": [
        "cell fixation method performance in viral vaccine quantitation assays",
        "use of formalin vs microwave irradiation for fixation",
        "time/equipment/chemical use in assay workflow"
    ],
    "main_findings": "Microwave irradiation was reported as an advantageous alternative to formalin fixation of cells before staining in viral vaccine quantitation assays, allowing avoidance of dangerous chemicals and reducing time and equipment.",
    "effect_direction": "unclear",
    "limitations": [
        "No exposure parameters (frequency, power, duration) reported in abstract",
        "No quantitative results or performance metrics reported in abstract",
        "Study design and sample size not described in abstract"
    ],
    "evidence_strength": "insufficient",
    "confidence": 0.66000000000000003108624468950438313186168670654296875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave irradiation",
        "microwave radiation",
        "cell fixation",
        "formalin fixation",
        "viral vaccine quantitation",
        "staining"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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