Effects of microwave radiation (340 and 900 MHz) on different structural levels of erythrocyte membranes.

PAPER pubmed Bioelectromagnetics 1985 In vitro study Effect: harm Evidence: Low

Read original paper → DOI: 10.1002/bem.2250060310 PMID: 3836673 Evidence Lab

Abstract

By use of fluorescence probes 1-anilinonaphthalene-8-sulfonic acid, 2-toluidinylnaphthalene-6-sulfonate, pyrene, perylene and chemical label phosphatidylethanolamine 2,4,6-trinitrobenzele sulfonic acid, the effect of microwave radiation on the erythrocyte membrane was studied. The studies with the fluorescence probes were carried out on erythrocyte ghosts and with 2,4,6-trinitrobenzene sulfonic acid on whole erythrocytes. The fluorescence was measured during irradiation of the membranes with 340-MHz microwaves at an SAR of 100 W/kg. Trinitrophenylation of phosphatidylethanolamine from whole erythrocytes was performed simultaneously with microwave irradiation at 900 MHz (10 mW/cm2). It was shown that the microwave field decreased lipid viscosity, altered the structural state of lipid-protein contact regions, and decreased the protein shielding of lipids. These changes corresponded to those produced by thermal action of microwaves.

AI evidence extraction

At a glance

Study type

In vitro study

Effect direction

harm

Population

—

Sample size

—

Exposure

RF · 900 MHz · 100 W/kg

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

During irradiation, 340-MHz microwaves (SAR 100 W/kg) decreased lipid viscosity, altered the structural state of lipid-protein contact regions, and decreased protein shielding of lipids in erythrocyte membranes. Similar changes were observed during 900-MHz irradiation (10 mW/cm2) during trinitrophenylation, and the reported changes corresponded to those produced by thermal action of microwaves.

Outcomes measured

erythrocyte membrane lipid viscosity
structural state of lipid-protein contact regions
protein shielding of lipids
trinitrophenylation of phosphatidylethanolamine

Limitations

No sample size reported in abstract.
Exposure duration not reported.
Temperature control/measurement details not reported; authors note correspondence with thermal action.
In vitro/isolated membrane preparation (erythrocyte ghosts) limits direct inference to in vivo health outcomes.

View raw extracted JSON

{
    "study_type": "in_vitro",
    "exposure": {
        "band": "RF",
        "source": null,
        "frequency_mhz": 900,
        "sar_wkg": 100,
        "duration": null
    },
    "population": null,
    "sample_size": null,
    "outcomes": [
        "erythrocyte membrane lipid viscosity",
        "structural state of lipid-protein contact regions",
        "protein shielding of lipids",
        "trinitrophenylation of phosphatidylethanolamine"
    ],
    "main_findings": "During irradiation, 340-MHz microwaves (SAR 100 W/kg) decreased lipid viscosity, altered the structural state of lipid-protein contact regions, and decreased protein shielding of lipids in erythrocyte membranes. Similar changes were observed during 900-MHz irradiation (10 mW/cm2) during trinitrophenylation, and the reported changes corresponded to those produced by thermal action of microwaves.",
    "effect_direction": "harm",
    "limitations": [
        "No sample size reported in abstract.",
        "Exposure duration not reported.",
        "Temperature control/measurement details not reported; authors note correspondence with thermal action.",
        "In vitro/isolated membrane preparation (erythrocyte ghosts) limits direct inference to in vivo health outcomes."
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave radiation",
        "340 MHz",
        "900 MHz",
        "SAR 100 W/kg",
        "10 mW/cm2",
        "erythrocyte membrane",
        "erythrocyte ghosts",
        "fluorescence probes",
        "lipid viscosity",
        "lipid-protein interactions",
        "thermal effects"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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