The relation of dose rate of microwave radiation to the time of death and total absorbed dose in the mouse.

Abstract

This experiment demonstrates that for microwave radiation, absorbed dose determination alone is not dosimetrically sufficient. The average absorbed dose to death in this experiment increases as the rate of absorption decreases. This observation is not surprising since microwave energy produces heating of the biological tissues. Hence, with a higher rate of heating the body of an animal, the less it is able to retain homeostasis through metabolic regulation than with a lower rate of heating. The absorbed dose rate and the duration of exposure must both be determined in any microwave biological effects experiments.

AI evidence extraction

Main findings

In mice exposed to microwave radiation, the average absorbed dose to death increased as the rate of absorption decreased, indicating that absorbed dose alone was not sufficient for dosimetry. The authors attribute this to tissue heating and reduced ability to maintain homeostasis at higher heating rates, and conclude that both absorbed dose rate and exposure duration should be determined in microwave bioeffects experiments.

Outcomes measured

• time of death
• total absorbed dose to death
• absorbed dose rate (rate of absorption)
• heating/thermoregulatory homeostasis

Limitations

• No frequency, exposure setup/source, or quantitative dose-rate/duration details provided in the abstract.
• Sample size and statistical methods are not reported in the abstract.
• Findings are framed in terms of thermal effects; non-thermal effects are not addressed in the abstract.

Suggested hubs

• occupational-exposure (0.15)
  Microwave exposure and dosimetry concepts may be relevant to occupational RF safety, though no occupational setting is described.

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": "mouse",
    "sample_size": null,
    "outcomes": [
        "time of death",
        "total absorbed dose to death",
        "absorbed dose rate (rate of absorption)",
        "heating/thermoregulatory homeostasis"
    ],
    "main_findings": "In mice exposed to microwave radiation, the average absorbed dose to death increased as the rate of absorption decreased, indicating that absorbed dose alone was not sufficient for dosimetry. The authors attribute this to tissue heating and reduced ability to maintain homeostasis at higher heating rates, and conclude that both absorbed dose rate and exposure duration should be determined in microwave bioeffects experiments.",
    "effect_direction": "harm",
    "limitations": [
        "No frequency, exposure setup/source, or quantitative dose-rate/duration details provided in the abstract.",
        "Sample size and statistical methods are not reported in the abstract.",
        "Findings are framed in terms of thermal effects; non-thermal effects are not addressed in the abstract."
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave radiation",
        "dose rate",
        "absorbed dose",
        "dosimetry",
        "thermal effects",
        "heating",
        "mouse",
        "time to death",
        "homeostasis"
    ],
    "suggested_hubs": [
        {
            "slug": "occupational-exposure",
            "weight": 0.1499999999999999944488848768742172978818416595458984375,
            "reason": "Microwave exposure and dosimetry concepts may be relevant to occupational RF safety, though no occupational setting is described."
        }
    ]
}

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