In vitro study of microwave effects on calcium efflux in rat brain tissue.

PAPER pubmed Bioelectromagnetics 1981 In vitro study Effect: no_effect Evidence: Low

Read original paper → DOI: 10.1002/bem.2250020207 PMID: 7295363 Evidence Lab

Abstract

In this study we investigated the prospect of microwave-induced alteration of 45Ca2+ efflux from rat neural tissue at low pulse repetition frequencies and low power densities under in vitro conditions. Rat cerebral tissue, preloaded with 45Ca2+, was exposed to pulsed-microwave radiation (1-GHz carrier frequency) according to one of several PRF-power density exposure schemes: 16 Hz at 0.5, 1.0, 2.0, or 15 mW/cm2, or 32 Hz at 1.0 or 2.0 mW/cm2 average power density. Measurements of radioactivity in the efflux medium and in the tissue sample were used to calculate an efflux value for each sample. The results indicate that the radiation conditions used did not alter calcium efflux in rat brain tissue.

AI evidence extraction

At a glance

Study type

In vitro study

Effect direction

no_effect

Population

Rat cerebral (brain) tissue (in vitro), preloaded with 45Ca2+

Sample size

—

Exposure

microwave · 1000 MHz

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

Rat cerebral tissue exposed in vitro to pulsed microwave radiation (1 GHz) at low pulse repetition frequencies (16 or 32 Hz) and average power densities ranging from 0.5 to 15 mW/cm2 showed no alteration in 45Ca2+ efflux compared with controls.

Outcomes measured

45Ca2+ (calcium) efflux from rat neural tissue

Limitations

Sample size not reported in abstract.
Exposure duration not reported in abstract.
Specific control/sham conditions and statistical methods not described in abstract.
Only calcium efflux outcome assessed; generalizability to other endpoints is unclear from abstract.

View raw extracted JSON

{
    "study_type": "in_vitro",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 1000,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Rat cerebral (brain) tissue (in vitro), preloaded with 45Ca2+",
    "sample_size": null,
    "outcomes": [
        "45Ca2+ (calcium) efflux from rat neural tissue"
    ],
    "main_findings": "Rat cerebral tissue exposed in vitro to pulsed microwave radiation (1 GHz) at low pulse repetition frequencies (16 or 32 Hz) and average power densities ranging from 0.5 to 15 mW/cm2 showed no alteration in 45Ca2+ efflux compared with controls.",
    "effect_direction": "no_effect",
    "limitations": [
        "Sample size not reported in abstract.",
        "Exposure duration not reported in abstract.",
        "Specific control/sham conditions and statistical methods not described in abstract.",
        "Only calcium efflux outcome assessed; generalizability to other endpoints is unclear from abstract."
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "in vitro",
        "microwave",
        "pulsed microwave",
        "1 GHz",
        "pulse repetition frequency",
        "power density",
        "rat brain tissue",
        "cerebral tissue",
        "calcium efflux",
        "45Ca2+"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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