The effect of exposure of acetylcholinesterase to 2,450-MHz microwave radiation.

PAPER pubmed Bioelectromagnetics 1984 In vitro study Effect: no_effect Evidence: Low

Read original paper → DOI: 10.1002/bem.2250050205 PMID: 6732873 Evidence Lab

Abstract

The effect of 2,450-MHz pulsed microwave radiation on the enzyme activity of membrane-free acetylcholinesterase was studied while the enzyme was in the microwave field. We found no significant effect of microwave radiation on enzyme activity using a wide variety of power densities, pulse widths, repetition rates, and duty cycles. This suggests that simple, direct modification by microwave energy of acetylcholinesterase structure and enzymic activity is not related to microwave alteration of acetylcholinesterase central nervous system levels.

AI evidence extraction

At a glance

Study type

In vitro study

Effect direction

no_effect

Population

—

Sample size

—

Exposure

microwave · 2450 MHz

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

In membrane-free acetylcholinesterase exposed in-field to 2,450-MHz pulsed microwave radiation, no significant changes in enzyme activity were observed across a range of power densities, pulse widths, repetition rates, and duty cycles.

Outcomes measured

acetylcholinesterase enzyme activity

Limitations

Sample size not reported in abstract.
Exposure metrics (e.g., specific power densities, SAR) not quantified in abstract.
Only membrane-free enzyme activity assessed; may not represent in vivo or CNS conditions.

View raw extracted JSON

{
    "study_type": "in_vitro",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": null
    },
    "population": null,
    "sample_size": null,
    "outcomes": [
        "acetylcholinesterase enzyme activity"
    ],
    "main_findings": "In membrane-free acetylcholinesterase exposed in-field to 2,450-MHz pulsed microwave radiation, no significant changes in enzyme activity were observed across a range of power densities, pulse widths, repetition rates, and duty cycles.",
    "effect_direction": "no_effect",
    "limitations": [
        "Sample size not reported in abstract.",
        "Exposure metrics (e.g., specific power densities, SAR) not quantified in abstract.",
        "Only membrane-free enzyme activity assessed; may not represent in vivo or CNS conditions."
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "2450 MHz",
        "microwave radiation",
        "pulsed microwaves",
        "acetylcholinesterase",
        "enzyme activity",
        "in vitro"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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