Exposure to a 50 Hz electromagnetic field induces activation of the Epstein-Barr virus genome in latently infected human lymphoid cells.

PAPER pubmed Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 1997 In vitro study Effect: harm Evidence: Very low

Read original paper → PMID: 9276003 Evidence Lab

Abstract

The EBV genome in latently infected lymphoid cells offers an opportunity to follow effects on the transcriptional and translational product clearly distinguishable from those of the host cell genome. Exposure of Akata cells, a human lymphoid cell line latently infected by the EBV genome, to a 50 Hz EMF resulted in an increased number of cells expressing the virus early antigens. This finding provides additional evidence that DNA can be modulated by a magnetic field.

AI evidence extraction

At a glance

Study type

In vitro study

Effect direction

harm

Population

Akata cells (human lymphoid cell line latently infected with Epstein–Barr virus genome)

Sample size

—

Exposure

ELF · 0.05 MHz

Evidence strength

Very low

Confidence: 72% · Peer-reviewed: yes

Main findings

Exposure of Akata cells latently infected with EBV to a 50 Hz electromagnetic field increased the number of cells expressing EBV early antigens.

Outcomes measured

Number of cells expressing Epstein–Barr virus (EBV) early antigens (activation of EBV genome)

Limitations

In vitro cell line study; findings may not generalize to humans or in vivo conditions
Exposure parameters beyond frequency (e.g., field strength, duration) not provided in abstract
Sample size and statistical details not reported in abstract

Suggested hubs

elf-emf (0.9)
Study examines biological effects of 50 Hz (ELF) electromagnetic field exposure.

View raw extracted JSON

{
    "study_type": "in_vitro",
    "exposure": {
        "band": "ELF",
        "source": null,
        "frequency_mhz": 0.05000000000000000277555756156289135105907917022705078125,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Akata cells (human lymphoid cell line latently infected with Epstein–Barr virus genome)",
    "sample_size": null,
    "outcomes": [
        "Number of cells expressing Epstein–Barr virus (EBV) early antigens (activation of EBV genome)"
    ],
    "main_findings": "Exposure of Akata cells latently infected with EBV to a 50 Hz electromagnetic field increased the number of cells expressing EBV early antigens.",
    "effect_direction": "harm",
    "limitations": [
        "In vitro cell line study; findings may not generalize to humans or in vivo conditions",
        "Exposure parameters beyond frequency (e.g., field strength, duration) not provided in abstract",
        "Sample size and statistical details not reported in abstract"
    ],
    "evidence_strength": "very_low",
    "confidence": 0.7199999999999999733546474089962430298328399658203125,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "50 Hz",
        "ELF electromagnetic field",
        "magnetic field",
        "Epstein-Barr virus",
        "EBV",
        "latent infection",
        "Akata cells",
        "early antigens",
        "viral activation",
        "lymphoid cells"
    ],
    "suggested_hubs": [
        {
            "slug": "elf-emf",
            "weight": 0.90000000000000002220446049250313080847263336181640625,
            "reason": "Study examines biological effects of 50 Hz (ELF) electromagnetic field exposure."
        }
    ]
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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