Influence of a 60 Hz, 3 microT, electromagnetic field on the somatic maturation of wistar rat offspring fed a regional basic diet during pregnancy.

Abstract

The aim of the present study was to observe how the exposition of pregnant rats to an electromagnetic field (EMF), with frequency of 60 Hz, and a magnetic field of 3 microT for 2 hours per day and/or using the so-called Regional Basic Diet (RBD), influenced the somatic maturation in their offspring. Four groups were formed: Group A (casein), B (casein and EMF), C (RBD) and D (RBD and EMF). The diet manipulation occurred during pregnancy. The somatic maturation indexes--assessed daily between 12:00 AM and 2:00 PM--were: Eye Opening (EO), Auricle Opening (AO), Auditory Canal Opening (ACO), Low Incisor Eruption (LIE), and Upper Incisor Eruption (UIE). The association between EMF and deficient diet caused a delay in all Somatic Maturation Indexes (SMI) and the RBD caused delay only in the AO. Furthermore, the EMF caused delay in AO, ACO, LIE. In relation to the body weight, the EMF associated with the deficient diet caused change in the twenty-first day of life. The RBD, during pregnancy, caused lower body weight in the offspring in the first and third day of life. The body weight of the offspring whose mothers were fed casein and exposed to the EMF during pregnancy was lower in the third and sixth day of life. In conclusion, the EMF associated with under-nutrition caused delay in all SMI. In relation to the body weight, the EMF associated with under-nutrition caused a decrease in the body weight at the sixth day of life.

AI evidence extraction

Main findings

In offspring, the combination of EMF exposure (60 Hz; 3 microT; 2 h/day during pregnancy) and a deficient diet (Regional Basic Diet) was associated with delays in all assessed somatic maturation indexes. EMF exposure was associated with delays in auricle opening, auditory canal opening, and low incisor eruption; the deficient diet alone delayed auricle opening. Various decreases/changes in offspring body weight were reported in early postnatal days, including with EMF plus deficient diet.

Outcomes measured

• Somatic maturation indexes (Eye Opening, Auricle Opening, Auditory Canal Opening, Low Incisor Eruption, Upper Incisor Eruption)
• Offspring body weight (postnatal days 1, 3, 6, 21 mentioned)

Limitations

• Sample size not reported in the abstract
• Details of exposure setup and dosimetry beyond frequency and magnetic flux density not provided
• Statistical methods and effect sizes not described in the abstract
• Timing and magnitude of body-weight effects are inconsistently described across days in the abstract

Suggested hubs

• occupational-exposure (0.2)
  ELF (60 Hz) magnetic-field exposure paradigm could be relevant to occupational/ambient power-frequency exposure, though the study is in rats.

{
    "study_type": "animal",
    "exposure": {
        "band": "ELF",
        "source": null,
        "frequency_mhz": 0.059999999999999997779553950749686919152736663818359375,
        "sar_wkg": null,
        "duration": "2 hours/day during pregnancy"
    },
    "population": "Pregnant Wistar rats and their offspring",
    "sample_size": null,
    "outcomes": [
        "Somatic maturation indexes (Eye Opening, Auricle Opening, Auditory Canal Opening, Low Incisor Eruption, Upper Incisor Eruption)",
        "Offspring body weight (postnatal days 1, 3, 6, 21 mentioned)"
    ],
    "main_findings": "In offspring, the combination of EMF exposure (60 Hz; 3 microT; 2 h/day during pregnancy) and a deficient diet (Regional Basic Diet) was associated with delays in all assessed somatic maturation indexes. EMF exposure was associated with delays in auricle opening, auditory canal opening, and low incisor eruption; the deficient diet alone delayed auricle opening. Various decreases/changes in offspring body weight were reported in early postnatal days, including with EMF plus deficient diet.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in the abstract",
        "Details of exposure setup and dosimetry beyond frequency and magnetic flux density not provided",
        "Statistical methods and effect sizes not described in the abstract",
        "Timing and magnitude of body-weight effects are inconsistently described across days in the abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "60 Hz",
        "3 microT",
        "ELF magnetic field",
        "pregnancy",
        "Wistar rat",
        "regional basic diet",
        "undernutrition",
        "somatic maturation",
        "development",
        "body weight"
    ],
    "suggested_hubs": [
        {
            "slug": "occupational-exposure",
            "weight": 0.200000000000000011102230246251565404236316680908203125,
            "reason": "ELF (60 Hz) magnetic-field exposure paradigm could be relevant to occupational/ambient power-frequency exposure, though the study is in rats."
        }
    ]
}

Comments

Log in to comment.

No comments yet.