[Mechanism of anesthetic action of magnetic fields].
Abstract
The dehydration effect is suggested as a mechanism of anesthetic action of magnetic fields. After half an hour of in vivo exposure in constant magnetic field of white male rats to SMF 0.2 T the dehydration of brain, kidney and liver tissues were detected, the decrease of ouabain binding in 5.10(-9) M concentration was detected in brain, heart, spleen and liver tissues and it was increased in kidney tissue. With prolongation of the exposure time the dehydration of the whole organism was observed.
AI evidence extraction
Main findings
After 30 minutes of in vivo exposure of white male rats to a constant static magnetic field (SMF) of 0.2 T, dehydration was detected in brain, kidney, and liver tissues. Ouabain binding at 5×10^-9 M decreased in brain, heart, spleen, and liver tissues and increased in kidney tissue; with longer exposure, dehydration of the whole organism was observed.
Outcomes measured
- Tissue dehydration (brain, kidney, liver)
- Ouabain binding changes in tissues (brain, heart, spleen, liver, kidney)
- Whole-organism dehydration with prolonged exposure
Limitations
- Sample size not reported in abstract
- Comparative design details and control conditions not described in abstract
- Exposure duration beyond 30 minutes not quantified in abstract
- Mechanistic interpretation (dehydration as anesthetic mechanism) is suggested rather than demonstrated in abstract
View raw extracted JSON
{
"study_type": "animal",
"exposure": {
"band": null,
"source": "static magnetic field (SMF)",
"frequency_mhz": null,
"sar_wkg": null,
"duration": "30 minutes (with mention of prolonged exposure time)"
},
"population": "White male rats (in vivo)",
"sample_size": null,
"outcomes": [
"Tissue dehydration (brain, kidney, liver)",
"Ouabain binding changes in tissues (brain, heart, spleen, liver, kidney)",
"Whole-organism dehydration with prolonged exposure"
],
"main_findings": "After 30 minutes of in vivo exposure of white male rats to a constant static magnetic field (SMF) of 0.2 T, dehydration was detected in brain, kidney, and liver tissues. Ouabain binding at 5×10^-9 M decreased in brain, heart, spleen, and liver tissues and increased in kidney tissue; with longer exposure, dehydration of the whole organism was observed.",
"effect_direction": "harm",
"limitations": [
"Sample size not reported in abstract",
"Comparative design details and control conditions not described in abstract",
"Exposure duration beyond 30 minutes not quantified in abstract",
"Mechanistic interpretation (dehydration as anesthetic mechanism) is suggested rather than demonstrated in abstract"
],
"evidence_strength": "low",
"confidence": 0.7399999999999999911182158029987476766109466552734375,
"peer_reviewed_likely": "yes",
"keywords": [
"static magnetic field",
"SMF",
"0.2 T",
"rats",
"dehydration",
"ouabain binding",
"mechanism",
"anesthetic action"
],
"suggested_hubs": []
}
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