Effects of static magnetic field on growth of leptospire, Leptospira interrogans serovar canicola: immunoreactivity and cell division.

PAPER pubmed Journal of bioscience and bioengineering 2004 In vitro study Effect: harm Evidence: Low

Read original paper → DOI: 10.1016/s1389-1723(04)00263-4 PMID: 16233687 Evidence Lab

Abstract

The effects of the exposure of the bacterium, Leptospira interrogans serovar canicola to a constant magnetic field with magnetic flux density from a permanent ferrite magnet=140+/-5 mT were studied. Changes in Leptospira cells after their exposure to the field were determined on the basis of changes in their growth behavior and agglutination immunoreactivity with a homologous antiserum using dark-field microscopy together with visual imaging. The data showed that the exposed Leptospira cells have lower densities and lower agglutination immunoreactivity than the unexposed control group. Interestingly, some of the exposed Leptospira cells showed abnormal morphologies such as large lengths. We discussed some of the possible reasons for these observations.

AI evidence extraction

At a glance

Study type

In vitro study

Effect direction

harm

Population

Leptospira interrogans serovar canicola (bacterium)

Sample size

—

Exposure

static permanent ferrite magnet

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

Leptospira cells exposed to a constant magnetic field (140±5 mT) showed lower densities and lower agglutination immunoreactivity compared with unexposed controls. Some exposed cells showed abnormal morphology (e.g., increased length).

Outcomes measured

growth behavior/cell density
agglutination immunoreactivity with homologous antiserum
cell morphology (abnormal length)

Limitations

Exposure duration not reported in abstract
Sample size and number of replicates not reported in abstract
Methods rely on dark-field microscopy/visual imaging; quantitative measurement details not provided in abstract

View raw extracted JSON

{
    "study_type": "in_vitro",
    "exposure": {
        "band": "static",
        "source": "permanent ferrite magnet",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Leptospira interrogans serovar canicola (bacterium)",
    "sample_size": null,
    "outcomes": [
        "growth behavior/cell density",
        "agglutination immunoreactivity with homologous antiserum",
        "cell morphology (abnormal length)"
    ],
    "main_findings": "Leptospira cells exposed to a constant magnetic field (140±5 mT) showed lower densities and lower agglutination immunoreactivity compared with unexposed controls. Some exposed cells showed abnormal morphology (e.g., increased length).",
    "effect_direction": "harm",
    "limitations": [
        "Exposure duration not reported in abstract",
        "Sample size and number of replicates not reported in abstract",
        "Methods rely on dark-field microscopy/visual imaging; quantitative measurement details not provided in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "static magnetic field",
        "permanent ferrite magnet",
        "140 mT",
        "Leptospira interrogans",
        "immunoreactivity",
        "agglutination",
        "cell division",
        "morphology",
        "in vitro"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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