[The liver rupture following radiofrequency ablation of relapsing hepatocellular carcinoma].

Abstract

The authors present a case of a liver rupture after radiofrequency ablation (RFA) of the hepatocellular carcinoma (HCC) relaps, following left-sided hepatectomy. The rupture resulted from major termoablation within the hepatic venous region, followed by the liver edema, to which incomplete hepatic venous outflow thrombosis, diagnosed prior to the procedure, contributed. Due to the extensive progressive subcupsular hematoma and hemoperitoneum, surgical revision with the liver tamponade was performed. The female patient recovered with no complications. However, 4 months after the RFA, the HCC became generalized. The authors discuss serious complications of the RFA, which have a frequency rate of 3% or less in major study groups, and of which the intraabdominal bleeding has the highest rate.

AI evidence extraction

Main findings

A liver rupture occurred after radiofrequency ablation of relapsing hepatocellular carcinoma, associated with major thermoablation in the hepatic venous region and contributing incomplete hepatic venous outflow thrombosis. Surgical revision with liver tamponade was performed and the patient recovered without complications; however, the cancer became generalized 4 months after RFA.

Outcomes measured

• Liver rupture
• Subcapsular hematoma
• Hemoperitoneum
• Recovery after surgical revision/tamponade
• Cancer generalization at 4 months

Limitations

• Single-patient case report
• No quantitative exposure parameters (e.g., frequency, power, SAR) reported
• Clinical context includes pre-existing incomplete hepatic venous outflow thrombosis, limiting attribution

{
    "study_type": "case_report",
    "exposure": {
        "band": null,
        "source": "radiofrequency ablation (medical procedure)",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Female patient with relapsing hepatocellular carcinoma after left-sided hepatectomy",
    "sample_size": 1,
    "outcomes": [
        "Liver rupture",
        "Subcapsular hematoma",
        "Hemoperitoneum",
        "Recovery after surgical revision/tamponade",
        "Cancer generalization at 4 months"
    ],
    "main_findings": "A liver rupture occurred after radiofrequency ablation of relapsing hepatocellular carcinoma, associated with major thermoablation in the hepatic venous region and contributing incomplete hepatic venous outflow thrombosis. Surgical revision with liver tamponade was performed and the patient recovered without complications; however, the cancer became generalized 4 months after RFA.",
    "effect_direction": "harm",
    "limitations": [
        "Single-patient case report",
        "No quantitative exposure parameters (e.g., frequency, power, SAR) reported",
        "Clinical context includes pre-existing incomplete hepatic venous outflow thrombosis, limiting attribution"
    ],
    "evidence_strength": "very_low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "radiofrequency ablation",
        "RFA",
        "hepatocellular carcinoma",
        "liver rupture",
        "complication",
        "intraabdominal bleeding",
        "hematoma",
        "hemoperitoneum",
        "hepatectomy",
        "thrombosis"
    ],
    "suggested_hubs": []
}

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