Effect of different intensities of static magnetic field on stress & reproduction in Zebrafish

PAPER manual 2019 Animal study Effect: harm Evidence: Low

Read original paper → DOI: 10.1007/s00128-018-02538-1 Evidence Lab

Abstract

Effect of different intensities of static magnetic field on stress & reproduction in Zebrafish Sedigh E, Heidari B, Roozati A, Valipour A. The effect of different intensities of static magnetic field on stress and selected reproductive indices of the Zebrafish (Danio rerio) during acute and subacute exposure. Bull Environ Contam Toxicol. 2019 Jan 9. doi: 10.1007/s00128-018-02538-1. Abstract The application of equipment and tools that produce a magnetic field is increasing in aquatic ecosystems. In the present study, the effects of acute (1 week) and subacute (3 weeks) exposures to different static magnetic fields (SMFs) of 2.5, 5, 7.5 mT on stress indices (cortisol and glucose), sex steroid hormones (17β-estradiol and 17-α hydroxy progesterone) and fecundity of the zebrafish (Danio rerio) were investigated. The obtained results showed a significant change in cortisol, glucose, 17β-estradiol (E2) and 17-α hydroxy progesterone (17-OHP) levels by enhancing the intensity and time of exposure to SMFs. In conclusion, the SMFs, especially at higher levels of intensities, showed physiologically harmful effects on the reproductive biology of the zebrafish during acute and subacute exposure. ncbi.nlm.nih.gov

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Zebrafish (Danio rerio)

Sample size

—

Exposure

static · acute (1 week) and subacute (3 weeks)

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

Acute (1 week) and subacute (3 weeks) exposure to static magnetic fields of 2.5, 5, and 7.5 mT was associated with significant changes in cortisol, glucose, 17β-estradiol, and 17-α hydroxy progesterone levels, with effects increasing with field intensity and exposure time. The authors conclude that higher-intensity SMFs showed physiologically harmful effects on zebrafish reproductive biology during these exposures.

Outcomes measured

cortisol
glucose
17β-estradiol (E2)
17-α hydroxy progesterone (17-OHP)
fecundity
stress indices
sex steroid hormones
selected reproductive indices

Limitations

Sample size not reported in abstract
Details of exposure setup and controls not described in abstract
Fecundity results not quantified in abstract

Suggested hubs

occupational-exposure (0.2)
Mentions increasing use of equipment/tools producing magnetic fields; study evaluates biological effects of static magnetic fields (though in an aquatic animal model).

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "static",
        "source": null,
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": "acute (1 week) and subacute (3 weeks)"
    },
    "population": "Zebrafish (Danio rerio)",
    "sample_size": null,
    "outcomes": [
        "cortisol",
        "glucose",
        "17β-estradiol (E2)",
        "17-α hydroxy progesterone (17-OHP)",
        "fecundity",
        "stress indices",
        "sex steroid hormones",
        "selected reproductive indices"
    ],
    "main_findings": "Acute (1 week) and subacute (3 weeks) exposure to static magnetic fields of 2.5, 5, and 7.5 mT was associated with significant changes in cortisol, glucose, 17β-estradiol, and 17-α hydroxy progesterone levels, with effects increasing with field intensity and exposure time. The authors conclude that higher-intensity SMFs showed physiologically harmful effects on zebrafish reproductive biology during these exposures.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in abstract",
        "Details of exposure setup and controls not described in abstract",
        "Fecundity results not quantified in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "static magnetic field",
        "SMF",
        "mT",
        "zebrafish",
        "Danio rerio",
        "stress",
        "cortisol",
        "glucose",
        "reproduction",
        "fecundity",
        "estradiol",
        "progesterone",
        "acute exposure",
        "subacute exposure"
    ],
    "suggested_hubs": [
        {
            "slug": "occupational-exposure",
            "weight": 0.200000000000000011102230246251565404236316680908203125,
            "reason": "Mentions increasing use of equipment/tools producing magnetic fields; study evaluates biological effects of static magnetic fields (though in an aquatic animal model)."
        }
    ]
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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