RF Safe argues that findings it describes as “high-certainty” from WHO-commissioned systematic reviews show RF-EMF causes malignant heart Schwannomas and brain gliomas in rodents and reduces male fertility. The post proposes a unifying non-thermal mechanism—the “S4-mitochondria axis”—suggesting RF-EMF interacts with the voltage-sensing S4 helix of voltage-gated ion channels (VGICs) and is amplified by mitochondrial density. It concludes that the combination of animal evidence and a proposed mechanism supports precautionary revisions to exposure guidelines and more mechanistic research.

This animal study examined Wi-Fi RF-EMR exposure in adult zebrafish (4 hours/day for 30 days) and assessed reproductive tissues and offspring outcomes. The abstract reports testicular and ovarian histopathological abnormalities in exposed adults. Offspring from exposed parents, maintained under EMF-free conditions, reportedly showed increased mortality, morphological abnormalities, and anxiety-like behavior, with malformations increasing with longer parental exposure.

This controlled laboratory study examined sex-specific behavioral responses of juvenile shore crabs to magnetic fields intended to represent submarine power cable EMFs. Females showed consistent attraction to EMF-exposed zones across 500–3,200 μT exposures, whereas males showed no consistent spatial preference. The authors suggest such sex-specific sensitivity could disrupt female-driven behaviors relevant to migration and reproduction, with potential ecological implications.