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Filters: tag: Histopathology Clear

Effect of dual RF-EMF and pulsed magnetic field exposure on eNOS expression and histological integrity in male rat reproductive tissues.

Research RF Safe Research Library Jan 1, 2026

This rat study examined combined RF-EMF and pulsed magnetic field exposure across multiple dosing schedules up to one month, assessing reproductive and related tissues with RT-qPCR, histopathology, and immunohistochemistry. The authors report increased eNOS expression with minimal VEGF change and generally preserved…

NTP Lite: The Japan-Korea Collaborative RF Exposure Toxicity Project [Health Matters]

Research RF Safe Research Library Jan 1, 2025

This magazine article reviews the Japan-Korea "NTP Lite" RF animal toxicity collaboration and its relationship to prior NTP (2018) and Ramazzini Institute reports of RF-associated tumors in male rats. It notes NTP Lite used a single whole-body SAR of 4 W/kg and completed a two-year exposure phase in 2022, but final…

The effect of alpha-lipoic acid on liver damage induced by extremely low-frequency electromagnetic fields in a rat model

Research RF Safe Research Library Jan 1, 2025

This rat study assessed whether alpha-lipoic acid (ALA) modifies liver effects from extremely low-frequency magnetic field (ELF-MF) exposure. ELF-MF exposure (2 mT, 4 hours/day for 30 days) was associated with increased liver pathology and higher apoptosis markers (TUNEL, caspase-3) compared with other groups. ALA…

Genotoxic and histopathological effects of 6 GHz radiofrequency electromagnetic radiation on rat liver tissue

Research RF Safe Research Library Jan 1, 2025

This animal experiment exposed adult male rats to 6 GHz RF-EMR (0.065 W/kg) for 4 hours/day over 42 days and compared them with sham controls. The exposed group showed higher comet assay genotoxicity metrics, though not statistically significant, and more prominent liver histopathological changes (e.g., portal…

The influence of Wi-Fi on the mesonephros in the 9-day-old chicken embryo

Research RF Safe Research Library Jan 1, 2025

This animal study examined continual 2.4 GHz Wi‑Fi exposure (200–500 μW/m²) during 9 days of chicken embryo incubation and assessed the mesonephros at day 9. The authors report no adverse effects on general mesonephros development, but describe moderate degenerative changes and vascular congestion without…

Effects of non-ionizing radiation on the thyroid gland in rats

Research RF Safe Research Library Jan 1, 2025

This animal study exposed Sprague-Dawley rats (including pregnant females and offspring) to 2.45 GHz Wi-Fi or mobile jammer radiation for 2 hours daily over two weeks and assessed thyroid hormones and thyroid histology. The abstract reports significant changes in T4 in exposed adult males and significant differences…

The effect on rat peripheral nerve morphology and function of a 900-MHz electromagnetic field applied in the prenatal period

Research RF Safe Research Library Jan 1, 2025

This animal study exposed pregnant Sprague Dawley rats to a 900 MHz electromagnetic field for 1 hour daily throughout gestation and assessed offspring outcomes postnatally. Sciatic nerve analyses at postnatal day 60 indicated persistent morphological alterations attributed to prenatal EMF exposure. However, the…

Prophylactic Effects of Radiofrequency Electromagnetic Field on Pulmonary Ischemia-Reperfusion via HIF-1α/eNOS Pathway and BCL2/BAX Signaling.

Research RF Safe Research Library Jan 1, 2025

This animal study tested whether RF-EMF exposure modifies lung ischemia-reperfusion injury in male Wistar rats. IR increased histologic injury, inflammatory/apoptotic markers, oxidative stress indices, and Hif-1α/eNOS/BAX while decreasing BCL2. The IR + RF-EMF group reportedly improved across measured parameters, and…

Evaluation of the Thyroids of Offsprings Exposed to 2450 MHz Radiofrequency Radiation During Pregnancy: A Sixth Month Data

Research RF Safe Research Library Jan 1, 2024

This animal study examined whether continuous prenatal exposure to 2450 MHz radiofrequency radiation (simulating Wi‑Fi) affects thyroid tissue in rat offspring at 6 months. The exposed group showed significantly increased mononuclear cell infiltration and vascular congestion in thyroid histology. TUNEL-positive cell…

Ameliorative effects of crocin against electromagnetic field-induced oxidative stress and liver and kidney injuries in mice.

Research RF Safe Research Library Jan 1, 2023

This mouse experiment evaluated whether crocin (50 mg/kg) mitigates liver and kidney injury associated with 2100 MHz electromagnetic field exposure. EMF exposure was associated with increased serum markers of kidney and liver injury, reduced antioxidant enzyme activity, and histopathological/ultrastructural changes…

Hazardous effects of high voltage electromagnetic field on albino rats and protective role of Rosmarinus officinalis.

Research RF Safe Research Library Jan 1, 2022

This animal study examined effects of a 50 Hz high-voltage electromagnetic field (5.4 kV/m) applied 2 or 4 hours per day for 25 days in albino rats. The authors report decreases in RBC, haemoglobin, and catalase activity, with increases in WBCs, liver enzymes, bilirubin, kidney-related markers, and malondialdehyde…

The effects of prenatal and postnatal exposure to electromagnetic field on rat ovarian tissue.

Research RF Safe Research Library Jan 1, 2020

This animal study examined prenatal-to-postnatal exposure to a 50-Hz, 3-mT electromagnetic field and ovarian development in female rat offspring. At 42 days of age, the EMF group had higher FSH, lower estradiol, higher iNOS levels/expression, and histological signs of ovarian tissue damage compared with sham. The…

Combined Effects of Radiofrequency Electromagnetic Fields and X-Ray in Renal Tissue and Function.

Research RF Safe Research Library Jan 1, 2020

This animal experiment randomized 96 male Wistar rats to RF-EMF exposures (900/1800 MHz mobile phone or 2.4 GHz Wi-Fi), 8 Gy x-ray, or combinations, and assessed kidney function markers and histopathology. Creatinine was reported significantly higher and the BUN/Cr ratio significantly lower in the Wi-Fi group versus…

Assessment of function, histopathological changes, and oxidative stress in liver tissue due to ionizing and non-ionizing radiations.

Research RF Safe Research Library Jan 1, 2020

This animal study evaluated liver function, histopathology, and oxidative stress markers after exposure to RF-EMF (900/1800 MHz and 2.4 GHz), x-rays (10 cGy or 8 Gy), and combinations including RF-EMF pre-exposure. Some liver enzymes (AST, ALT, ALP) showed some association with irradiation, while…

Long-Term Study on the Effects of Housing C57BL/6NCrl Mice in Cages Equipped With Wireless Technology Generating Extremely Low-Intensity Electromagnetic Fields.

Research RF Safe Research Library Jan 1, 2019

This animal study characterized electromagnetic fields generated by digitally ventilated mouse cages with wireless monitoring technology and assessed clinicopathological outcomes over up to 1 year. DVC produced extremely low-intensity electric fields across a wide frequency range (5 Hz to 3 GHz). The authors report…

Effect of Modified Wuzi Yanzong Pill () on Tip60-Mediated Apoptosis in Testis of Male Rats after Microwave Radiation.

Research RF Safe Research Library Jan 1, 2019

This animal study exposed male rats to a single 15-minute microwave radiation session and assessed testicular apoptosis, histopathology, and related proteins. The radiation group showed increased apoptosis and testicular structural alterations versus controls at multiple time points, while a modified Wuzi Yanzong…

Effect of 900-MHz Electromagnetic Field on the Cerebellum: A Histopathological Investigation.

Research RF Safe Research Library Jan 1, 2018

This animal study evaluated histopathological effects of 900-MHz RF-EMF exposure on the rat cerebellum. The exposed group showed intense caspase-3 expression in Purkinje and granular cells and histological changes consistent with apoptosis. Cerebellar layer thickness appeared reduced in exposed animals, although…

The effects of microwave radiation on rabbit's retina.

Research RF Safe Research Library Jan 1, 2018

This experimental rabbit study evaluated retinal effects of GSM cell phone simulator microwave irradiation at different distances and durations. ERG outcomes 7 days after exposure showed no statistically significant differences between groups, although irradiated eyes showed non-significant trends toward greater…

Effect of 2.45 GHz microwave radiation on the fertility pattern in male mice.

Research RF Safe Research Library Jan 1, 2018

This animal study examined 2.45 GHz microwave exposure in male Swiss albino mice for 2 hours per day over 30 days. The authors report increased oxidative stress markers and reduced antioxidant enzymes and testosterone in exposed mice versus sham controls. They also report micronuclei formation in blood and…

Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats.

Research RF Safe Research Library Jan 1, 2017

This animal study examined whole-body exposure to 2.45 GHz microwave radiation for 2 h/day over 35 days in male Wistar rats. The authors report increased lipid peroxidation (LPO) in liver, brain, and spleen and histological changes across multiple organs compared with sham-exposed controls. They conclude the exposure…

Impacts of exposure to 900 MHz mobile phone radiation on liver function in rats.

Research RF Safe Research Library Jan 1, 2015

This animal experiment randomized 20 male Sprague-Dawley rats to 900 MHz electromagnetic radiation exposure (4 h/day for 18 days) or no exposure. The exposed group showed increased oxidative stress markers in liver tissue (higher MDA, lower GSH) and reported histopathological changes, along with increased apoptosis…

[Endoscopic pleomorphic adenoma of nasal septum resection assisted by low-temperature plasm radiofrequency: a case report].

Research RF Safe Research Library Jan 1, 2014

This case report describes a 24-year-old woman with a rare pleomorphic adenoma of the nasal septum. The tumor was identified on CT imaging, diagnosed by incisional biopsy, and removed endoscopically with histology confirming pleomorphic adenoma. The report focuses on clinical management rather than evaluating…

Autophagy and enhanced chemosensitivity in experimental pancreatic cancers induced by noninvasive radiofrequency field treatment.

Research RF Safe Research Library Jan 1, 2014

This study tested noninvasive 13.56 MHz radiofrequency electric fields as a treatment adjunct for pancreatic ductal adenocarcinoma in cell lines and mouse xenograft models. The authors report RF exposure caused cytotoxicity in PDAC cells via autophagy (not apoptosis) and that normal pancreatic ductal epithelial cells…

Effect of radiofrequency microtenotomy on degeneration of tendons: an experimental study on rabbits.

Research RF Safe Research Library Jan 1, 2014

This experimental rabbit study evaluated radiofrequency microtenotomy (Rf-mt) in prostaglandin E1-induced Achilles tendon degeneration. Rf-mt increased vascularity based on histopathology and immunohistochemistry. However, the authors report no significant difference in tendon healing compared with a sham-control…

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