A multicenter case-control study in Iran reported that self-reported prolonged mobile phone use was associated with higher odds of confirmed and suspected breast cancer status. The authors emphasize that the findings do not imply causation and note limitations including self-reported exposure and potential residual confounding. They call for larger prospective studies with objective exposure assessment.

This two-sample Mendelian randomization study examined whether duration of mobile phone use is causally related to aneurysmal subarachnoid hemorrhage using large European GWAS datasets. The primary MR analysis reported that excessive duration of mobile phone use was associated with higher aSAH risk, and sensitivity analyses were described as supportive. The authors conclude the findings have potential clinical, public health, and policy implications.

This multicenter case-control study in Iran (n=226) examined associations between mobile phone use and breast cancer outcomes in women. Reporting more than 60 minutes/day of phone conversations was associated with higher odds of confirmed invasive breast cancer and of being classified as a suspected case versus <10 minutes/day. The authors emphasize that the results do not establish causation and may be influenced by self-reported exposure and residual confounding, warranting cautious interpretation.

This Mendelian randomization study assessed whether duration of mobile phone use is causally related to stroke outcomes using GWAS-derived SNP instruments. The inverse-variance weighted analysis reported a significant increased risk for large artery atherosclerosis (LAAS) with longer mobile phone use duration, while other stroke outcomes showed no significant associations. Sensitivity analyses (including MR-Egger and heterogeneity/asymmetry tests) were reported as suggesting the LAAS finding was robust.

This pooled analysis of two prior human studies reports increased odds of prostate cancer associated with mobile phone use, with higher estimates for longer latency and higher cumulative hours. Cordless phone use is reported to show increased risk but not statistically significant overall, with one mid-range cumulative use category showing an elevated OR. The abstract also reports higher risks among men with more aggressive prostate cancer and among those with a family history of prostate cancer.

This 2016 narrative review proposes that non-thermal microwave/lower-frequency EMFs act primarily through activation of voltage-gated calcium channels (VGCCs), with calcium channel blockers reported to block EMF effects. It summarizes animal, occupational, and epidemiological literature and reports that exposures from base stations, heavy mobile phone use, and wireless smart meters are associated with neuropsychiatric symptoms, sometimes with doseresponse patterns. The author concludes that multiple lines of evidence collectively support that non-thermal microwave EMF exposures can produce diverse neuropsychiatric effects including depression.

This narrative review discusses potential public health consequences of widespread mobile phone use and the controversy around long-term cancer risks. It states that evidence from epidemiological and experimental studies suggests long-term exposure to mobile phone emissions may be linked to a small to moderate increased risk of certain cancers, while also emphasizing that data are insufficient for a final risk assessment. The author argues that even small risks could matter at the population level and that exposure-reduction measures may be indicated given uncertainties.