Regulation of skeletal myogenesis in C2C12 cells through modulation of Pax7, MyoD, and myogenin via different low-frequency electromagnetic field energies.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study examined how low-frequency electromagnetic fields (LF-EMF) at different magnetic flux densities influence skeletal myogenesis in C2C12 cells. The authors report that 2.0 mT LF-EMF activated cells and increased PAX7, while 1.5 mT increased MyoD and myogenin expression. They conclude that different…
Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study evaluated short-term extremely low frequency electromagnetic field (ELF-EMF) exposure and silver nanoparticles (AgNPs), alone and combined, for antibacterial effects and apoptosis induction in MCF-7 breast cancer cells. The authors report time-dependent reductions in bacterial viable counts, with…
Comparing the Effects of Long-term Exposure to Extremely Low-frequency Electromagnetic Fields With Different Values on Learning, Memory, Anxiety, and β-amyloid Deposition in Adult Rats.
Research
RF Safe Research Library
Jan 1, 2021
This animal study exposed adult male rats to 50 Hz ELF-EMF at 1, 100, 500, or 2000 μT for 1 hour/day over two months and assessed behavior and brain markers. The authors report increased memory retention (higher step-through latency) alongside increased anxiety-like behavior (reduced open-arm entries), particularly…
Effects of excessive use of mobile phone technology in India on human health during COVID-19 lockdown.
Research
RF Safe Research Library
Jan 1, 2021
This cross-sectional online survey study (n=122) examined increased dependency on mobile phone technology and electronic gadgets in India during the COVID-19 lockdown. Most participants reported increased usage and perceived increased risk of health problems from excessive use. The authors conclude that technology…
The Time-Dependence of Three Different Modes of ELF-EMF Stimulation on LTP at Schaffer Collateral-CA1 Synapses.
Research
RF Safe Research Library
Jan 1, 2021
This animal ex vivo study tested whether short-term 15 Hz/2 mT ELF-EMF exposure alters LTP at rat hippocampal SC-CA1 synapses. Across sinusoidal, pulsed, and rhythm-pulsed modes, the authors report reduced LTP versus control, with greater inhibition at longer exposure durations (10–60 s). Sinusoidal stimulation…
Radiofrequency EMF irradiation effects on pre-B lymphocytes undergoing somatic recombination.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed developing pre-B lymphocytes undergoing V(D)J recombination to low-intensity RF EMFs for 48 hours across 720–1224 MHz. The authors report a frequency- and dose-dependent decrease in recombination, with stronger reductions around 950–1000 MHz at relatively low power densities. γH2AX levels…
Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.
Research
RF Safe Research Library
Jan 1, 2021
This review examines temperature-independent (non-thermal) effects of RF and microwave electromagnetic fields, emphasizing antiproliferative effects relevant to oncology. It summarizes preclinical and clinical literature on conventional RF hyperthermia and amplitude-modulated RF hyperthermia and argues that evidence…
and Exposed to Wi-Fi Radiofrequency Electromagnetic Radiation Show Enhanced Growth and Lactic Acid Production.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro experimental study exposed two Lactobacillus probiotic cultures to 2.4 GHz Wi‑Fi RF-EMF from a router for 15–60 minutes and compared them with sham-exposed controls. The authors report increased bacterial growth after 30–60 minutes of exposure, with no growth difference at 15 minutes. Lactic acid…
Microtubular structure impairment after GSM-modulated RF radiation exposure.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study exposed V79 cells to 915 MHz GSM-modulated RF radiation for 1–3 hours at 10–30 V/m (average SARs reported as 0.23–1.6 W/kg). The authors report that 3-hour exposure altered microtubule structure across all tested field strengths and reduced cell growth on the third post-exposure day. They conclude…
Electromagnetic field affects the voltage-dependent potassium channel Kv1.3.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study tested whether extremely low-frequency electromagnetic fields (ELF-EMF) modulate the voltage-gated potassium channel Kv1.3 in Kv1.3-expressing CHO-K1 cells. Cells were exposed to a 20 Hz field at 268 µT or 902 µT while Kv1.3 currents were measured by whole-cell patch clamp. The authors report a…
Effects of pulse-modulated radiofrequency magnetic field (RF-EMF) exposure on apoptosis, autophagy, oxidative stress and electron chain transport function in human neuroblastoma and murine microglial cells.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study exposed murine microglial (N9) and human neuroblastoma (SH-SY5Y) cells to ELF-modulated 935 MHz RF-EMF at 4 W/kg for 2 or 24 hours. The authors report no changes in apoptosis, cell viability, or AIF across conditions. They report increased ATG5 after 24 hours and a transient glutathione increase…
Treating honey bees with an extremely low frequency electromagnetic field and pesticides: Impact on the rate of disappearance of azoxystrobin and λ-cyhalothrin and the structure of some functional groups of the probabilistic molecules.
Research
RF Safe Research Library
Jan 1, 2020
This laboratory study examined whether 50 Hz (ELF) electromagnetic field exposure changes pesticide disappearance rates and molecular functional group signatures in honey bees. EMF altered the disappearance rates of azoxystrobin and λ-cyhalothrin within 6 hours, with different patterns depending on whether pesticides…
Radiofrequency applicator concepts for thermal magnetic resonance of brain tumors at 297 MHz (7.0 Tesla).
Research
RF Safe Research Library
Jan 1, 2020
This engineering/simulation study evaluates RF applicator concepts for ThermalMR brain tumor heating at 297 MHz (7.0 Tesla) using clinically realistic GBM-based models. EMF simulations compared 10 applicator designs and two SAR-based planning algorithms for small and large target volumes. Power-focused optimization…
Exploring the form- And time-dependent effect of low-frequency electromagnetic fields on maintenance of hippocampal long-term potentiation.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study developed an MEA-compatible magnetic stimulation device to deliver low-frequency EMFs during hippocampal LTP experiments without interrupting induction. The authors report that sine-wave LF-EMFs applied post-induction or as priming reduced fEPSP slope during LTP maintenance, with stronger effects…
Efficacy of Mobile Phone Short Message Service (SMS) Reminders on Malaria Treatment Adherence and Day 3 Post-Treatment Reviews (SMS-RES-MAL) in Kenya: A Study Protocol.
Research
RF Safe Research Library
Jan 1, 2019
This protocol describes a proof-of-concept open-label randomized controlled trial in Western Kenya assessing whether SMS reminders added to standard care improve malaria treatment adherence and day 3 post-treatment review attendance. Caregivers of children under five with uncomplicated malaria will be randomized to…
Impact of electromagnetic fields on in vitro toxicity of silver and graphene nanoparticles.
Research
RF Safe Research Library
Jan 1, 2019
This in vitro study examined whether RF electromagnetic fields (900, 2400, 7500 MHz) modify the toxicity of silver and graphene nanoparticles in human fibroblast cultures. The authors report EMF-associated changes in cytotoxicity and ROS that depended on nanoparticle type, shape, and concentration, with the strongest…
Low-frequency electromagnetic fields as an alternative to sanitize water of drinking systems in poultry production?
Research
RF Safe Research Library
Jan 1, 2019
This study tested pulsed low-frequency electromagnetic fields (up to 10,000 Hz; max 21 mT) as a potential alternative sanitation approach for poultry drinking water systems. LF-EMF exposure was linked to variable changes in culturable bacterial counts, with direction depending on system type and some early…
Correlation between the Lunar Phase and Tail-Lifting Behavior of Lizards () Exposed to an Extremely Low-Frequency Electromagnetic Field.
Research
RF Safe Research Library
Jan 1, 2019
This animal study examined long-term tail-lifting behavior in agamid lizards exposed to an ELF electromagnetic field (6 and 8 Hz; peak magnetic field 2.6 µT; peak electric field 10 V/m) versus controls, incorporating lunar phase and geomagnetic activity (K index) as explanatory variables. Regression analyses found…
Geobacter sulfurreducens-inoculated bioelectrochemical system reveals the potential of metabolic current in defining the effect of extremely low-frequency electromagnetic field on living cells.
Research
RF Safe Research Library
Jan 1, 2019
This laboratory study exposed a Geobacter sulfurreducens-inoculated bioelectrochemical system to 0–128 Gauss extremely low-frequency electromagnetic fields. The authors report increased and oscillatory metabolic current under ELF-EMF exposure, with dose-dependent effects and a linear relationship between oscillation…
Hepatocellular carcinoma therapy finds a channel on the radio
Research
RF Safe Research Library
Jan 1, 2019
This EBioMedicine commentary discusses tumour-specific amplitude-modulated RF EMF as an anti-cancer therapy for hepatocellular carcinoma and highlights Cav3.2 (CACNA1H) T-type calcium channels as a proposed mediator of the effect. It notes that the reported whole-body averaged SAR in a treated HCC patient was below…
Electromagnetic Fields of Mobile Phone Jammer Exposure on Blood Factors in Rats.
Research
RF Safe Research Library
Jan 1, 2018
This rat study examined whether electromagnetic fields from a mobile phone jammer affect blood cell factors. Rats were exposed 8 hours/day, 5 days/week for 40 days and compared with control and sham groups. The authors report significant changes in multiple hematological indices, with some measures unchanged…
A 60 Hz uniform electromagnetic field promotes human cell proliferation by decreasing intracellular reactive oxygen species levels.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study examined effects of a 6 mT, 60 Hz uniform ELF electromagnetic field on HeLa cells and primary IMR-90 fibroblasts. Single or repetitive exposure did not induce DNA damage or change viability, but continuous exposure over 168 hours was reported to increase proliferation in both cell types in a…
Extremely low frequency electromagnetic fields promote mesenchymal stem cell migration by increasing intracellular Ca and activating the FAK/Rho GTPases signaling pathways in vitro.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human bone marrow-derived mesenchymal stem cells to extremely low frequency EMF (7.5–70 Hz, 1 mT) generated by Helmholtz coils. The authors report increased MSC migration across all tested frequencies. Mechanistically, the effect is described as dependent on intracellular calcium and…
Expressions of some antioxidant genes in SH-SY5Y cells treated with β-lapachone, morphine and electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed SH-SY5Y cells to a 50 Hz, 0.50 mT electromagnetic field under intermittent or continuous conditions, alongside β-lapachone and/or morphine. The authors report condition-dependent changes in antioxidant gene expression, including decreased NQO1 and increased NQO2 under intermittent EMF…
Important parameters for optimized metal nanoparticles-aided electromagnetic field (EMF) effect on cancer.
Research
RF Safe Research Library
Jan 1, 2018
This paper presents a theoretical model analyzing parameters that may optimize metal nanoparticle-aided EMF photothermal therapy effects on cancer cells. The model suggests efficacy depends on both electric field enhancement and thermal (hyperthermia) contributions, influenced by nanoparticle absorption properties…