The Use of Induction Sensors and Helmet-Based Shielding Technology to Identify Differences in Electromagnetic Fields in Patients With Cranial Neurological Disease Versus Healthy Controls.
Research
RF Safe Research Library
Jan 1, 2023
This observational study used induction sensors with a Mu-metal and copper mesh shielded helmet to measure cortically generated EMFs in patients with cranial neurological disease and compare patterns to previously obtained healthy control data. Fourteen patients (ages 14–81) were analyzed and compared with four…
NET Formation Was Reduced via Exposure to Extremely Low-Frequency Pulsed Electromagnetic Fields.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study examined whether a 16 Hz extremely low-frequency pulsed electromagnetic field (ELF-PEMF) affects neutrophil extracellular trap (NET) formation. In neutrophils from healthy volunteers, ELF-PEMF exposure did not induce ROS or calcium influx and did not increase basal or PMA-induced NET formation.…
The Effect of Low-Frequency Pulsed Electromagnetic Fields on the Differentiation of Permanent Dental Pulp Stem Cells into Odontoblasts.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed dental pulp mesenchymal stem cells to 50 Hz pulsed electromagnetic fields at 0.5 or 1 mT for 20 or 40 minutes per day over seven days. Cell survival/proliferation was generally higher than control across exposure groups, except for the 40 minutes/day at 1 mT condition. DMP1 expression was…
Human osteosarcoma cells in response to ELF-MF: Morphological remodeling compared to cell proliferation.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed human osteosarcoma (MG-63) cells to 2 mT extremely low-frequency magnetic fields with sinusoidal, triangular, or pulsed waveforms under continuous (3 h) or fractionated (3 days) conditions. The authors report significant decreases in proliferation and shape index in exposed cells versus…
A Swine Model of Neural Circuit Electromagnetic Fields: Effects of Immediate Electromagnetic Field Stimulation on Cortical Injury.
Research
RF Safe Research Library
Jan 1, 2023
This animal study used non-contact induction sensors and a shielded helmet to measure cortical EMF patterns in a Yucatan miniswine before and after traumatic brain injury induced by controlled cortical impact. The authors report that targeted low-frequency EMF stimulation initiated 20 minutes post-injury was…
Personal exposure to radiofrequency electromagnetic fields in various occupations in Spain and France.
Research
RF Safe Research Library
Jan 1, 2023
This study conducted personal full-shift RF-EMF measurements in 333 workers across 46 occupations in Spain and France. Most 1-second measurements of electric and magnetic fields were below the device detection limit (≥1% of 1998 ICNIRP standards), though many workers had at least one detectable reading. A small…
Seed Treatment with Electromagnetic Field Induces Different Effects on Emergence, Growth and Profiles of Biochemical Compounds in Seven Half-Sib Families of Silver Birch.
Research
RF Safe Research Library
Jan 1, 2023
This study evaluated a short (1 min) electromagnetic field (EMF) seed treatment in seven half-sib families of silver birch and assessed emergence, growth, and leaf biochemical profiles in one- and two-year-old seedlings. The abstract reports genotype- and age-dependent responses, with some families showing…
The Effect of Extremely Low-Frequency Electromagnetic Fields on Inflammation and Performance-Related Indices in Trained Athletes: A Double-Blinded Crossover Study.
Research
RF Safe Research Library
Jan 1, 2023
This double-blinded crossover study tested an ELF-EMF mattress used immediately after high-intensity cycling and overnight in nine trained male athletes. The authors report no significant overall effects on performance and inflammation. However, between 60 minutes and 24 hours post-exercise, the active condition…
Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study examined NIH/3T3 fibroblast cells exposed to 2100 MHz EMF and evaluated cell viability, cyclin D1, and NF-κB activity, with and without 200 nM selenium. The abstract reports reduced cell viability and increased cyclin D1 and NF-κB activity after EMF exposure. Selenium supplementation was reported…
A Swine Model of Traumatic Brain Injury: Effects of Neuronally Generated Electromagnetic Fields and Electromagnetic Field Stimulation on Traumatic Brain Injury-Related Changes.
Research
RF Safe Research Library
Jan 1, 2023
This animal feasibility study evaluated whether real-time measured, targeted sinusoidal EMF stimulation could normalize traumatic brain injury (TBI)-related changes in neuronally generated EMF patterns. In one Yucatan miniswine with controlled cortical impact, AI modeling distinguished pre-injury, post-injury, and…
A Novel and Versatile Microfluidic Device for Cell Assays under Radio Frequency Exposure.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study describes a microfluidic device integrated with a radiofrequency exposure system to enable on-chip monitoring of cellular responses under a 1.8 GHz field. Using human amniotic epithelial cells, the authors report field-intensity-associated increases in protrusions/filopodia, changes in…
It is the Frequency that Matters: Effects of Electromagnetic Fields on the Release and Content of Extracellular Vesicles.
Research
RF Safe Research Library
Jan 1, 2023
This preprint describes an in vitro bioreactor-based system to test whether electromagnetic/electrical stimulation affects extracellular vesicles (EVs). Using proteomics and single-vesicle flow cytometry, the authors report that stimulation at physiological current amplitudes can modulate EV content in a…
A Swine Model of Changes in the Neuronal Electromagnetic Field After Traumatic Brain Injury: A Pilot Study.
Research
RF Safe Research Library
Jan 1, 2023
This pilot swine study evaluated whether non-contact proprietary induction sensors in a Mu-metal/copper mesh helmet can measure endogenous neuronal EMF signals before and after controlled cortical impact traumatic brain injury. The authors report that swine EMF recordings were distinguishable from room noise and…
Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue.
Research
RF Safe Research Library
Jan 1, 2023
This experimental mouse study tested whether N-acetylcysteine (NAC), pulsed electromagnetic fields (PEMF), or their combination improves outcomes after transplantation of vitrified ovarian tissue. The abstract reports increased follicle numbers and enhanced vascularization in NAC, PEMF, and NAC+PEMF groups, along…
Phagocytosis of latex beads by a human monocytic Mono Mac 6 cell line and effects of low-frequency electromagnetic field interaction.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study tested whether a low-frequency EMF (7 Hz, 30 mT) alters phagocytosis-related outcomes in the human monocytic Mono Mac 6 cell line. EMF exposure was associated with increased necrosis in cells pre-stimulated with SEB and then undergoing latex bead phagocytosis, while no significant cell-death…
Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Improves Neurological Outcome and Reduces Microglial Reactivity in a Rodent Model of Global Transient Stroke.
Research
RF Safe Research Library
Jan 1, 2023
This animal and laboratory study evaluated extremely low-frequency electromagnetic stimulation (ELF-EMS) in a rodent ischemia-reperfusion stroke model and related in vitro/slice experiments. The authors report improved neurological and behavioral outcomes, increased neuronal survival, and reduced glial/microglial…
Effect of electromagnetic fields from renewable energy subsea power cables on righting reflex and physiological response of coastal invertebrates.
Research
RF Safe Research Library
Jan 1, 2023
This study examined whether electromagnetic fields (EMF) similar to those from offshore renewable subsea export cables affect coastal invertebrates. It simulated a 500 μT EMF and measured righting reflex and selected physiological markers in four species. The authors report no significant behavioural or physiological…
P53 status, and G2/M cell cycle arrest, are determining factors in cell-death induction mediated by ELF-EMF in glioblastoma.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study tested ELF-EMF exposure in U87 and U251 glioblastoma cell lines and assessed apoptosis, cell-cycle distribution, cell size, and mRNA expression of cell-cycle genes. The authors report higher apoptosis induction and increased G2/M arrest in U87 compared with U251, alongside increased U87 cell size…
Extremely low-frequency electromagnetic field exposure alters DNA methylation levels in the endometrium of pigs during the peri-implantation period.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed porcine endometrial slices from the peri-implantation period (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed promoter DNA methylation in selected genes. The authors report increased methylation for EGR2, ID2, and PTGER4, decreased methylation for IL1RAP and NOS3, and no…
Cellular Mechanisms of Electromagnetic Field in Traumatic Brain Injury.
Research
RF Safe Research Library
Jan 1, 2023
This paper reviews literature from 1980–2023 on the role of electromagnetic fields as a therapy for traumatic brain injury and brain neuropathology. It reports that existing findings suggest electromagnetic therapy may be a promising non-invasive treatment approach. The authors emphasize that current evidence is…
Transcriptome profiling of flax plants exposed to a low-frequency alternating electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2023
This study aims to perform transcriptome profiling in flax plants exposed to a low-frequency alternating electromagnetic field. The abstract frames prior work as suggesting EMF-related changes in free radical homeostasis and altered expression of genes involved in stress responses, ion transport, and cell wall…
Ameliorative effects of crocin against electromagnetic field-induced oxidative stress and liver and kidney injuries in mice.
Research
RF Safe Research Library
Jan 1, 2023
This mouse experiment evaluated whether crocin (50 mg/kg) mitigates liver and kidney injury associated with 2100 MHz electromagnetic field exposure. EMF exposure was associated with increased serum markers of kidney and liver injury, reduced antioxidant enzyme activity, and histopathological/ultrastructural changes…
Synergistic cytotoxic effects of an extremely low-frequency electromagnetic field with doxorubicin on MCF-7 cell line.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study tested whether a 50 Hz, 20 mT extremely low-frequency electromagnetic field (ELF-EMF) enhances the cytotoxic effects of doxorubicin (DOX) in the MCF-7 breast cancer cell line. The authors report that combining ELF-EMF with low-dose DOX reduced cell viability at lower DOX concentrations than DOX…
Electromagnetic fields ameliorate hepatic lipid accumulation and oxidative stress: potential role of CaMKKβ/AMPK/SREBP-1c and Nrf2 pathways.
Research
RF Safe Research Library
Jan 1, 2023
This animal study examined EMF exposure in a mouse high-fat diet model of NAFLD. The authors report that EMF exposure reduced hepatic lipid accumulation and markers of oxidative stress, alongside changes consistent with activation of CaMKKβ/AMPK and Nrf2-related signaling. The abstract concludes EMF could be a…
EMAGINE-Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke.
Research
RF Safe Research Library
Jan 1, 2023
This paper presents the protocol for the EMAGINE multicenter, double-blind, randomized, sham-controlled trial testing an extremely low-frequency, low-intensity, frequency-tuned electromagnetic field therapy (ENTF) after subacute ischemic stroke. Participants will start active or sham treatment 4–21 days post-stroke,…