Exposure to hexavalent chromium and 1800 MHz electromagnetic radiation can synergistically induce intracellular DNA damage in mouse embryonic fibroblasts
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PubMed: RF-EMF health
Jan 31, 2026
This PubMed-listed in vitro study tested whether 1800 MHz RF-EMF exposure can modify chemically induced DNA damage in mouse embryonic fibroblasts under standardized, non-thermal conditions. The authors report RF-EMF alone did not produce detectable DNA damage and did not significantly increase damage from hydrogen…
The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study
Research
PubMed: RF-EMF health
Jan 13, 2026
This PubMed-listed animal study reports results from the Japanese arm of an international Japan–Korea collaboration evaluating whether long-term mobile-phone-like RF-EMF exposure causes cancer or genetic damage in rats. Male Sprague Dawley rats were exposed to 900 MHz CDMA-modulated RF-EMF at a whole-body SAR of 4…
The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study
Research
RF Safe Research Library
Jan 1, 2026
This international collaborative animal study (Japanese arm) evaluated carcinogenicity and genotoxicity in male Sprague Dawley rats exposed long-term to 900 MHz CDMA-modulated RF-EMFs at 4 W/kg whole-body SAR. The abstract reports no statistically significant increases in neoplastic or non-neoplastic lesions in major…
Exposure to hexavalent chromium and 1800 MHz electromagnetic radiation can synergistically induce intracellular DNA damage in mouse embryonic fibroblasts
Research
RF Safe Research Library
Jan 1, 2026
This in vitro study tested whether 1800 MHz RF-EMF modifies chemically induced DNA damage in mouse embryonic fibroblasts under non-thermal exposure conditions. RF-EMF alone did not produce detectable DNA damage and did not significantly enhance damage from hydrogen peroxide, 4NQO, or cadmium. In contrast, co-exposure…
The International Collaborative Animal Study of The Carcinogenicity and Genotoxicity of Mobile Phone Radiofrequency Radiation: The Korean Study.
Research
RF Safe Research Library
Jan 1, 2026
This chronic animal bioassay assessed carcinogenicity and genotoxicity of CDMA-modulated 900 MHz RF exposure at a whole-body SAR of 4 W/kg using a shared Korea–Japan protocol. Male Sprague-Dawley rats were exposed starting on gestational day 5 with daily intermittent exposure for long durations, including a 2-year…
Microwave and RF Exposure-Induced Molecular and Genetic Alterations
Research
RF Safe Research Library
Jan 1, 2025
This review discusses recent studies on microwave and RF exposure and their reported impacts on molecular and cytogenetic materials. It states there is growing evidence that RF exposure can induce DNA damage at levels considered safe by current standards, and cites newly reported genetic alterations in rat cancers…
Effect of electromagnetic radiations from mobile towers on genetic damage and genetic polymorphism in humans: a review on India's perspective
Research
RF Safe Research Library
Jan 1, 2025
This narrative review examines research on radiofrequency electromagnetic radiation (RF-EMR) from mobile towers and its potential association with genetic damage and genetic polymorphism in humans, with an emphasis on India. The abstract states that RF-EMR exposure may affect genetic material and suggests a link…
Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats
Research
RF Safe Research Library
Jan 1, 2025
This randomized controlled animal study examined chronic 35.5 GHz millimeter wave exposure in male Wistar rats (2 hours/day for 60 days) compared with control and sham groups. The exposed group showed reduced sperm count and viability along with testicular histopathological changes. Oxidative stress markers shifted…
A scoping review and evidence map of radiofrequency field exposure and genotoxicity: assessing in vivo, in vitro, and epidemiological data
Research
RF Safe Research Library
Jan 1, 2025
This scoping review and evidence map (PRISMA-ScR) summarizes over 500 studies on RF-EMF exposure and genotoxicity across in vitro, in vivo, and epidemiological research. The authors report a higher proportion of significant DNA damage findings in in vivo and epidemiological studies than in vitro studies, with DNA…
Genotoxic and histopathological effects of 6 GHz radiofrequency electromagnetic radiation on rat liver tissue
Research
RF Safe Research Library
Jan 1, 2025
This animal experiment exposed adult male rats to 6 GHz RF-EMR (0.065 W/kg) for 4 hours/day over 42 days and compared them with sham controls. The exposed group showed higher comet assay genotoxicity metrics, though not statistically significant, and more prominent liver histopathological changes (e.g., portal…
Assessing cell viability and genotoxicity in Trigonella foenum-graecum L. exposed to 2100 MHz and 2300 MHz electromagnetic field radiations.
Research
RF Safe Research Library
Jan 1, 2025
This experimental study assessed cytotoxic and genotoxic endpoints in Trigonella foenum-graecum L. exposed to 2100 MHz and 2300 MHz EMF-r for 0.5–8 h/day. The authors report reduced root/shoot growth at longer daily exposures, increased chromosomal aberrations compared with controls, and reduced cell viability.…
Exposure to mobile phone radiations at 2350 MHz incites cyto- and genotoxic effects in root meristems of .
Research
RF Safe Research Library
Jan 1, 2019
This experimental study exposed onion root meristems to continuous 2350 MHz radiofrequency EMF for 1, 2, or 4 hours and assessed cytotoxicity and genotoxicity. It reports increased mitotic index at 4 hours and increased chromosomal aberrations at exposures of 2 hours or longer, with some comet assay DNA distribution…
Genotoxic and cytotoxic effects of 50 Hz 1 mT electromagnetic field on larval rainbow trout (Oncorhynchus mykiss), Baltic clam (Limecola balthica) and common ragworm (Hediste diversicolor).
Research
RF Safe Research Library
Jan 1, 2019
This animal study assessed genotoxic and cytotoxic responses in aquatic species exposed to a 50 Hz, 1 mT electromagnetic field. Nuclear abnormality assays indicated significant increases in multiple genotoxicity endpoints across species, with the most pronounced effects in Baltic clam gill cells. Cytotoxicity…
Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones
Research
RF Safe Research Library
Jan 1, 2018
This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart,…
Evaluation of Cytotoxic and Genotoxic Effects of Extremely Low-frequency Electromagnetic Field on Mesenchymal Stromal Cells.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study evaluated whether a therapeutic extremely low-frequency EMF exposure (5 Hz, 0.4 mT) causes cytotoxic or genotoxic effects in a human mesenchymal stromal cell line. Cells were exposed for 20 minutes per day, three times per week, for two weeks and assessed for viability, proliferation, and…
Effects of 1800 MHz RF-EMF exposure on DNA damage and cellular functions in primary cultured neurogenic cells.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed primary cultured astrocytes, microglia, and cortical neurons to 1800 MHz RF-EMF at 4.0 W/kg SAR to assess DNA damage and cellular functions. The authors report no significant induction of γH2AX foci and no significant changes in cytokine secretion or dendrite/synapse morphological…
Effect of 2.45 GHz microwave radiation on the fertility pattern in male mice.
Research
RF Safe Research Library
Jan 1, 2018
This animal study examined 2.45 GHz microwave exposure in male Swiss albino mice for 2 hours per day over 30 days. The authors report increased oxidative stress markers and reduced antioxidant enzymes and testosterone in exposed mice versus sham controls. They also report micronuclei formation in blood and…
Genotoxic Effects in Human Fibroblasts Exposed to Microwave Radiation.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human fetal and adult fibroblasts to 25 GHz microwave radiation and assessed multiple genotoxic and cellular endpoints. The authors report no evidence of direct DNA damage and no apoptosis or changes in prosurvival signalling proteins. However, they report increased total and…
Oxidative and mutagenic effects of low intensity GSM 1800 MHz microwave radiation
Research
RF Safe Research Library
Jan 1, 2018
This animal study used developing quail embryos to assess oxidative and mutagenic effects of low-intensity GSM 1800 MHz radiation from a commercial smartphone. The authors report statistically significant increases in oxidative stress markers, DNA integrity damage, and oxidative DNA damage (8-oxo-dG) in exposed…
RF-EMF exposure at 1800 MHz did not elicit DNA damage or abnormal cellular behaviors in different neurogenic cells.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study assessed whether intermittent 1800 MHz RF-EMF exposure induces DNA damage or alters cellular behavior in three neurogenic cell lines. Cells were exposed at an average SAR of 4.0 W/kg for 1, 6, or 24 hours and evaluated for γH2AX foci, cell cycle progression, proliferation, and viability. The…
Is mobile phone radiation genotoxic? An analysis of micronucleus frequency in exfoliated buccal cells.
Research
RF Safe Research Library
Jan 1, 2017
This cross-sectional study assessed whether mobile phone-associated EMF exposure is associated with micronucleus frequency in exfoliated buccal cells. Among 86 healthy users aged 18–30, micronucleus frequency was not associated with duration of daily calls and did not differ significantly between the cheek on the…
Electromagnetic fields at a mobile phone frequency (900 MHz) trigger the onset of general stress response along with DNA modifications in Eisenia fetida earthworms.
Research
RF Safe Research Library
Jan 1, 2017
This animal study exposed Eisenia fetida earthworms to 900 MHz electromagnetic fields at 10–120 V/m for 2 hours (with additional tests of longer exposure, modulation, and recovery). The authors report significant DNA modifications across exposure treatments and a decrease in probe hybridisation sites persisting after…
Effect of long-term exposure to mobile phone radiation on alpha-Int1 gene sequence of Candida albicans.
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study evaluated whether long-term 900 MHz radiation exposure induces mutations in the alpha-Int1 gene of Candida albicans. Yeast samples were exposed for 10 to 490 hours at 4°C and compared with unexposed controls. Sequencing of the PCR-amplified alpha-Int1 fragment found no mutations in exposed samples…
A cross-sectional study on oxidative stress in workers exposed to extremely low frequency electromagnetic fields
Research
RF Safe Research Library
Jan 1, 2015
This cross-sectional study compared oxidative stress and genotoxicity biomarkers between 310 ELF-EMF-exposed inspection workers and 300 logistical staff controls. The authors report no statistically significant differences in antioxidant-related measures (T-AOC, GPx, SOD) or MDA, and no significant differences in…
Effect of 950 MHz UHF electromagnetic radiation on biomarkers of oxidative damage, metabolism of UFA and antioxidants in the livers of young rats of different ages
Research
RF Safe Research Library
Jan 1, 2014
This animal study exposed rats of different early-life ages to 950 MHz UHF electromagnetic radiation for 30 minutes per day (SAR 1.0–1.3 W/kg) across gestation and/or early postnatal periods. The authors report no evidence of oxidative stress by TBARS or protein carbonyls, but report changes in fatty acid…