[Structural and metabolic analysis of the reaction of the central nervous system to the combined action of microwave and ionizing radiations].

Abstract

Structural and functional changes in the central nervous system were shown to be the same with both microwave and ionizing radiation having different mechanism of action. When the two types of radiation were delivered in a combination the sequence of delivery was of a significant importance. Antagonism of the effects was noted when microwave radiation was delivered prior to gamma-radiation. The effect was synergistic when the exposure to microwaves followed gamma-irradiation.

AI evidence extraction

Main findings

Structural and functional changes in the central nervous system were reported to be similar for microwave and ionizing (gamma) radiation despite different mechanisms. With combined exposure, the sequence mattered: microwave before gamma showed antagonism, while microwaves after gamma showed synergism.

Outcomes measured

• Structural changes in the central nervous system
• Functional changes in the central nervous system
• Metabolic/functional response of the central nervous system (implied)
• Interaction effects between microwave and gamma (ionizing) radiation (antagonism/synergy depending on sequence)

Limitations

• No details provided on species/animal model in the abstract
• No exposure parameters reported (frequency, intensity/SAR, duration)
• No sample size or statistical details reported
• Outcomes are described generally without quantitative results

Suggested hubs

• who-icnirp (0.2)
  Addresses biological effects of RF/microwave exposure relevant to general EMF health evidence discussions, though not explicitly policy-focused.

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": null,
    "sample_size": null,
    "outcomes": [
        "Structural changes in the central nervous system",
        "Functional changes in the central nervous system",
        "Metabolic/functional response of the central nervous system (implied)",
        "Interaction effects between microwave and gamma (ionizing) radiation (antagonism/synergy depending on sequence)"
    ],
    "main_findings": "Structural and functional changes in the central nervous system were reported to be similar for microwave and ionizing (gamma) radiation despite different mechanisms. With combined exposure, the sequence mattered: microwave before gamma showed antagonism, while microwaves after gamma showed synergism.",
    "effect_direction": "mixed",
    "limitations": [
        "No details provided on species/animal model in the abstract",
        "No exposure parameters reported (frequency, intensity/SAR, duration)",
        "No sample size or statistical details reported",
        "Outcomes are described generally without quantitative results"
    ],
    "evidence_strength": "insufficient",
    "confidence": 0.61999999999999999555910790149937383830547332763671875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave radiation",
        "gamma radiation",
        "ionizing radiation",
        "combined exposure",
        "sequence effect",
        "central nervous system",
        "antagonism",
        "synergism"
    ],
    "suggested_hubs": [
        {
            "slug": "who-icnirp",
            "weight": 0.200000000000000011102230246251565404236316680908203125,
            "reason": "Addresses biological effects of RF/microwave exposure relevant to general EMF health evidence discussions, though not explicitly policy-focused."
        }
    ]
}

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