Effects of 900 MHz electromagnetic field on TSH and thyroid hormones in rats.

Abstract

In this study, the effects of exposure to a 900 megahertz (MHz) electromagnetic field (EMF) on serum thyroid stimulating hormone (TSH) and triiodothronine-thyroxin (T3-T4) hormones levels of adult male Sprague-Dawley rats were studied. Thirty rats were used in three independent groups, 10 of which were control (without stress and EMF), 10 of which were exposed to 900 MHz EMF and 10 of which were sham-exposed. The exposures were performed 30 min/day, for 5 days/week for 4 weeks to 900 MHz EMF. Sham-exposed animals were kept under the same environmental conditions as the study groups except with no EMF exposure. The concentration of TSH and T3-T4 hormones in the rat serum was measured by using an immunoradiometric assay (IRMA) method for TSH and a radio-immunoassay (RIA) method for T3 and T4 hormones. TSH values and T3-T4 at the 900 MHz EMF group were significantly lower than the sham-exposed group (p<0.01). There were no statistically significant differences in serum TSH values and T3-T4 hormone concentrations between the control and the sham-exposed group (p>0.05). These results indicate that 900 MHz EMF emitted by cellular telephones decrease serum TSH and T3-T4 levels.

AI evidence extraction

Main findings

In rats exposed to 900 MHz EMF, serum TSH and T3/T4 levels were significantly lower than in sham-exposed rats (p<0.01). No statistically significant differences were observed between control and sham-exposed groups (p>0.05).

Outcomes measured

• Serum thyroid stimulating hormone (TSH)
• Serum triiodothyronine (T3)
• Serum thyroxine (T4)

Limitations

• No specific absorption rate (SAR) or exposure intensity reported in the abstract
• Only adult male rats studied (generalizability limited)
• Short-term exposure period (4 weeks)

Suggested hubs

• mobile-phones (0.9)
  Study examines 900 MHz EMF emitted by cellular telephones.

{
    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": "mobile phone",
        "frequency_mhz": 900,
        "sar_wkg": null,
        "duration": "30 min/day, 5 days/week for 4 weeks"
    },
    "population": "Adult male Sprague-Dawley rats",
    "sample_size": 30,
    "outcomes": [
        "Serum thyroid stimulating hormone (TSH)",
        "Serum triiodothyronine (T3)",
        "Serum thyroxine (T4)"
    ],
    "main_findings": "In rats exposed to 900 MHz EMF, serum TSH and T3/T4 levels were significantly lower than in sham-exposed rats (p<0.01). No statistically significant differences were observed between control and sham-exposed groups (p>0.05).",
    "effect_direction": "harm",
    "limitations": [
        "No specific absorption rate (SAR) or exposure intensity reported in the abstract",
        "Only adult male rats studied (generalizability limited)",
        "Short-term exposure period (4 weeks)"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "900 MHz",
        "RF-EMF",
        "cellular telephone",
        "rats",
        "Sprague-Dawley",
        "thyroid stimulating hormone",
        "TSH",
        "triiodothyronine",
        "T3",
        "thyroxine",
        "T4",
        "endocrine"
    ],
    "suggested_hubs": [
        {
            "slug": "mobile-phones",
            "weight": 0.90000000000000002220446049250313080847263336181640625,
            "reason": "Study examines 900 MHz EMF emitted by cellular telephones."
        }
    ]
}

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