[Use of super-high frequency electromagnetic fields on intrarenal circulation and morphological status of health kidneys (experimental study)].

PAPER pubmed Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 2000 Animal study Effect: harm Evidence: Low

Read original paper → PMID: 11197654 Evidence Lab

Abstract

The experimental study investigated action of electromagnetic waves (84 mW/cm2 and 395 mW/cm2) on functional-morphological features of healthy kidney of female rats. A marked hemodynamic effect of decimetric waves is shown which operates via stimulation of intermediary zone with redistribution of intrarenal circulation. Disturbance of circulation occurs in dysregulation of the intrarenal blood flow under overstimulation of the organ circulation with 395 mW/cm2 decimetric waves. This entails disorders of hemodynamics, flebostasis, stromal edema, dystrophy of tubular epithelium, periglomerular sclerosis causing aseptic interstitial inflammation. This is also proved by levels of prostaglandin E2 in tissue of renal papillae. These findings should be considered in administration of decimetric waves in patients with renal inflammation.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Female rats (healthy kidneys)

Sample size

—

Exposure

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

In female rats, decimetric electromagnetic waves produced a marked hemodynamic effect with redistribution of intrarenal circulation. Exposure at 395 mW/cm2 was associated with dysregulation of intrarenal blood flow and morphological changes including hemodynamic disorders, flebostasis, stromal edema, tubular epithelial dystrophy, and periglomerular sclerosis with aseptic interstitial inflammation; prostaglandin E2 levels in renal papilla tissue were reported as supporting evidence.

Outcomes measured

Intrarenal circulation/hemodynamics
Renal morphology (stromal edema, tubular epithelial dystrophy, periglomerular sclerosis)
Aseptic interstitial inflammation
Prostaglandin E2 levels in renal papilla tissue

Limitations

Sample size not reported in abstract
Exposure frequency and duration not reported in abstract
Animal study; generalizability to humans not established in abstract
Details of experimental design (controls, randomization, blinding) not reported in abstract

Suggested hubs

rf-health-effects (0.7)
Animal experiment assessing renal functional and morphological effects of RF (decimetric) electromagnetic waves.

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": null,
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Female rats (healthy kidneys)",
    "sample_size": null,
    "outcomes": [
        "Intrarenal circulation/hemodynamics",
        "Renal morphology (stromal edema, tubular epithelial dystrophy, periglomerular sclerosis)",
        "Aseptic interstitial inflammation",
        "Prostaglandin E2 levels in renal papilla tissue"
    ],
    "main_findings": "In female rats, decimetric electromagnetic waves produced a marked hemodynamic effect with redistribution of intrarenal circulation. Exposure at 395 mW/cm2 was associated with dysregulation of intrarenal blood flow and morphological changes including hemodynamic disorders, flebostasis, stromal edema, tubular epithelial dystrophy, and periglomerular sclerosis with aseptic interstitial inflammation; prostaglandin E2 levels in renal papilla tissue were reported as supporting evidence.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in abstract",
        "Exposure frequency and duration not reported in abstract",
        "Animal study; generalizability to humans not established in abstract",
        "Details of experimental design (controls, randomization, blinding) not reported in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "decimetric waves",
        "super-high frequency electromagnetic fields",
        "rats",
        "kidney",
        "intrarenal circulation",
        "hemodynamics",
        "renal morphology",
        "prostaglandin E2",
        "interstitial inflammation"
    ],
    "suggested_hubs": [
        {
            "slug": "rf-health-effects",
            "weight": 0.6999999999999999555910790149937383830547332763671875,
            "reason": "Animal experiment assessing renal functional and morphological effects of RF (decimetric) electromagnetic waves."
        }
    ]
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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