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Mechanism first explanation of how the plasma membrane potential controls immune responses

An RF Safe article argues that plasma membrane potential (Vm) is a key control variable for immune cell behavior by shaping ion driving forces, especially Ca2+ influx through CRAC channels and K+ channel–mediated hyperpolarization. It describes proposed links between Vm-regulated ion flux and downstream immune…

Sensation of electric fields in the Drosophila melanogaster larva

This animal study reports that Drosophila melanogaster larvae can sense electric fields and exhibit robust electrotaxis toward the cathode in controlled environments. The authors identify head-tip sensory neurons required for this behavior and report calcium-imaging evidence that Gr66a-positive neurons encode field…