Exposure to hexavalent chromium and 1800 MHz electromagnetic radiation can synergistically induce intracellular DNA damage in mouse embryonic fibroblasts
Research
PubMed: RF-EMF health
Jan 31, 2026
This PubMed-listed in vitro study tested whether 1800 MHz RF-EMF exposure can modify chemically induced DNA damage in mouse embryonic fibroblasts under standardized, non-thermal conditions. The authors report RF-EMF alone did not produce detectable DNA damage and did not significantly increase damage from hydrogen…
The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study
Research
PubMed: RF-EMF health
Jan 13, 2026
This PubMed-listed animal study reports results from the Japanese arm of an international Japan–Korea collaboration evaluating whether long-term mobile-phone-like RF-EMF exposure causes cancer or genetic damage in rats. Male Sprague Dawley rats were exposed to 900 MHz CDMA-modulated RF-EMF at a whole-body SAR of 4…
The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study
Research
RF Safe Research Library
Jan 1, 2026
This international collaborative animal study (Japanese arm) evaluated carcinogenicity and genotoxicity in male Sprague Dawley rats exposed long-term to 900 MHz CDMA-modulated RF-EMFs at 4 W/kg whole-body SAR. The abstract reports no statistically significant increases in neoplastic or non-neoplastic lesions in major…
Exposure to hexavalent chromium and 1800 MHz electromagnetic radiation can synergistically induce intracellular DNA damage in mouse embryonic fibroblasts
Research
RF Safe Research Library
Jan 1, 2026
This in vitro study tested whether 1800 MHz RF-EMF modifies chemically induced DNA damage in mouse embryonic fibroblasts under non-thermal exposure conditions. RF-EMF alone did not produce detectable DNA damage and did not significantly enhance damage from hydrogen peroxide, 4NQO, or cadmium. In contrast, co-exposure…
Effects of Extremely Low Frequency Magnetic Field Exposure (50 Hz, 200 µT) on Cell Viability, DNA Damage and Micronucleus Formation of Human Skin Cells.
Research
RF Safe Research Library
Jan 1, 2026
This in vitro study tested whether 50 Hz extremely low frequency magnetic fields at 200 µT (rms) affect human skin cells (HaCaT). Using blinded, simultaneous exposure and sham-exposure for 2 or 24 hours, the authors assessed cell viability, DNA integrity, and micronucleus formation. The abstract reports no…
DNA Damage Analysis in Blood Tissue & Physiopathological Evaluation of the Effect of Quercetin on Kidney Tissue in 2600 MHz EMF Exposure
Research
RF Safe Research Library
Jan 1, 2025
This rat study assessed 30-day 2600 MHz EMF exposure effects on kidney tissue and DNA damage in blood lymphocytes, with an EMF+quercetin group included. Kidney histopathology and immunohistochemistry were reported as similar across groups, and oxidative stress markers did not significantly change. The EMF-only group…
Development and Testing of a Novel Whole-body Exposure System for Investigative Studies of Radiofrequency Radiation in Rodents (NIEHS)
Research
RF Safe Research Library
Jan 1, 2025
This NIEHS report describes the development and testing of a flexible whole-body radiofrequency radiation exposure system for rats and mice using updated signals relevant to wireless technologies. In 5-day studies with CDMA- and GSM-modulated signals, no visible behavioral responses were observed and comet assays…
Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats
Research
RF Safe Research Library
Jan 1, 2025
This randomized controlled animal study examined chronic 35.5 GHz millimeter wave exposure in male Wistar rats (2 hours/day for 60 days) compared with control and sham groups. The exposed group showed reduced sperm count and viability along with testicular histopathological changes. Oxidative stress markers shifted…
Genotoxic and histopathological effects of 6 GHz radiofrequency electromagnetic radiation on rat liver tissue
Research
RF Safe Research Library
Jan 1, 2025
This animal experiment exposed adult male rats to 6 GHz RF-EMR (0.065 W/kg) for 4 hours/day over 42 days and compared them with sham controls. The exposed group showed higher comet assay genotoxicity metrics, though not statistically significant, and more prominent liver histopathological changes (e.g., portal…
Investigation of the Effects of 2.45 GHz Near-Field EMF on Yeast
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study exposed yeast suspensions to 2.45 GHz near-field microwave radiation at 2 cm and 4 cm for 20 or 60 minutes. It reports oxidative-stress-related changes (reduced antioxidant activity with increased membrane permeability) after 20 minutes at 2 cm, an effect not reproduced by conventional heating.…
Effects of 700MHz radiofrequency radiation (5G lower band) on the reproductive parameters of female Wistar rats
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined short- and long-term 700 MHz (lower-band 5G) radiofrequency exposure in female Wistar rats, comparing control, sham, and exposed groups. It reports no DNA damage and no change in estrous cycle length, but increased ovarian oxidative stress markers in exposed animals. Long-term exposure was…
Exposure to mobile phone radiations at 2350 MHz incites cyto- and genotoxic effects in root meristems of .
Research
RF Safe Research Library
Jan 1, 2019
This experimental study exposed onion root meristems to continuous 2350 MHz radiofrequency EMF for 1, 2, or 4 hours and assessed cytotoxicity and genotoxicity. It reports increased mitotic index at 4 hours and increased chromosomal aberrations at exposures of 2 hours or longer, with some comet assay DNA distribution…
Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones
Research
RF Safe Research Library
Jan 1, 2018
This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart,…
Genotoxic Effects in Human Fibroblasts Exposed to Microwave Radiation.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human fetal and adult fibroblasts to 25 GHz microwave radiation and assessed multiple genotoxic and cellular endpoints. The authors report no evidence of direct DNA damage and no apoptosis or changes in prosurvival signalling proteins. However, they report increased total and…
[Synergistic inhibitory effect of static magnetic field and antitumor drugs on Hepa1-6 cells].
Research
RF Safe Research Library
Jan 1, 2015
This in vitro study tested whether a static magnetic field (SMF) could enhance the effects of cisplatin or adriamycin in Hepa1-6 tumor cells. The abstract reports that SMF combined with either drug increased growth inhibition and was associated with cell-cycle arrest, increased DNA damage, and more severe membrane…
Effect of 950 MHz UHF electromagnetic radiation on biomarkers of oxidative damage, metabolism of UFA and antioxidants in the livers of young rats of different ages
Research
RF Safe Research Library
Jan 1, 2014
This animal study exposed rats of different early-life ages to 950 MHz UHF electromagnetic radiation for 30 minutes per day (SAR 1.0–1.3 W/kg) across gestation and/or early postnatal periods. The authors report no evidence of oxidative stress by TBARS or protein carbonyls, but report changes in fatty acid…
Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects
Research
RF Safe Research Library
Jan 1, 2013
This narrative review argues that non-thermal biological effects of extremely low and microwave frequency EMFs may be mediated by activation of voltage-gated calcium channels (VGCCs). It cites 23 studies in which VGCC blockers reportedly block or reduce diverse EMF effects and proposes downstream…
Effect of electromagnetic radiofrequency radiation on the rats' brain, liver and kidney cells measured by comet assay.
Research
RF Safe Research Library
Jan 1, 2011
This animal study assessed DNA damage in rat brain, liver, and kidney cells after repeated whole-body exposure to 915 MHz GSM-modulated RF radiation (SAR 0.6 W/kg) using the comet assay. Tail length was slightly increased in brain cells and differed more notably in liver and kidney samples versus sham controls, while…
Electromagnetic fields and DNA damage
Research
RF Safe Research Library
Jan 1, 2009
This review discusses the comet assay and summarizes research on non-ionizing EMF exposure and DNA/chromosomal damage. It describes both positive and negative findings across studies, noting no consistent overall pattern for radiofrequency radiation (RFR). The authors nonetheless conclude that under certain exposure…