Electromagnetic Field Influence on the Bioavailability and Accumulation of Ketoprofen.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro/ex vivo study tested whether different magnetic-field configurations alter ketoprofen properties and its transdermal delivery in porcine skin using Franz diffusion cells. The authors report no change in ketoprofen molecular structure, but subtle changes in crystal structure and physicochemical…
Validation of Electromagnetic Field Sensor Performance Through Porcine Skulls: Implications for Neurostimulation and Recording Techniques.
Research
RF Safe Research Library
Jan 1, 2025
This animal validation study tested a Mu-metal-shielded helmet system with proprietary induction sensor stimulators for non-invasive recording and stimulation of neural electromagnetic activity through porcine skulls. The authors report that EMFs penetrated the swine skull and that sensor performance remained…
The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional…
Heating of metallic orthodontic devices during anti-aging treatment with vacuum and electromagnetic fields: In vitro study.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study evaluated heating of metallic orthodontic brackets/wires during an anti-aging treatment combining vacuum and electromagnetic fields (V-EMF). Using 20 resin-mouth setups covered with porcine muscle tissue, both beta-titanium and nickel-titanium wire groups showed about a 1.1°C temperature rise by…
Exposure to the extremely low-frequency electromagnetic field induces changes in the epigenetic regulation of gene expression in the endometrium.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed porcine endometrial slices from days 15–16 of pregnancy to a 50 Hz extremely low-frequency electromagnetic field for 2 hours. The authors report changes in several epigenetic-related markers, including DNA methylation machinery, histone-related measures (HDAC activity), global DNA…
Extremely low-frequency electromagnetic field exposure alters DNA methylation levels in the endometrium of pigs during the peri-implantation period.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed porcine endometrial slices from the peri-implantation period (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed promoter DNA methylation in selected genes. The authors report increased methylation for EGR2, ID2, and PTGER4, decreased methylation for IL1RAP and NOS3, and no…
Extremely low-frequency electromagnetic field (EMF) generates alterations in the synthesis and secretion of oestradiol-17β (E) in uterine tissues: An in vitro study.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed porcine endometrial and myometrial slices to extremely low-frequency EMF (50 or 120 Hz, 8 mT) for 2 or 4 hours, with or without progesterone. The authors report frequency- and time-dependent changes in oestradiol-17β secretion and CYP19A3 mRNA expression, with fewer changes when…
Subzero 12-hour Nonfreezing Cryopreservation of Porcine Heart in a Variable Magnetic Field.
Research
RF Safe Research Library
Jan 1, 2015
This animal organ-preservation study compared 12-hour porcine heart preservation at -3°C using a device generating a variable magnetic field versus conventional 4°C preservation. The subzero variable-magnetic-field condition showed higher myocardial ATP, lower lactate, and less mitochondrial ultrastructural damage…
In Vivo Wireless Monitoring System of Cardiovascular Force Data.
Research
RF Safe Research Library
Jan 1, 2015
This paper describes development of a fully implantable biotelemetry system that wirelessly transmits cardiac biomechanical force data along with ECG. The system uses a microcontroller with a bidirectional RF transceiver and was tested in a porcine model. The authors report successful transmission and recording of…
Evaluation of mulitprobe radiofrequency technology in a porcine model.
Research
RF Safe Research Library
Jan 1, 2007
This animal study evaluated two multiprobe radiofrequency ablation device approaches in pigs, including an impedance-based algorithm and clustered/combination probes with and without a switcher controller. The Pringle maneuver was associated with larger ablation volumes and shorter ablation times in one experiment,…