Archive
4 postsThe International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study
This international collaborative animal study (Japanese arm) evaluated carcinogenicity and genotoxicity in male Sprague Dawley rats exposed long-term to 900 MHz CDMA-modulated RF-EMFs at 4 W/kg whole-body SAR. The abstract reports no statistically significant increases in neoplastic or non-neoplastic lesions in major organs and no evidence of genotoxicity on comet or micronucleus testing. The authors conclude the findings provide strong evidence of no reproducible carcinogenic or genotoxic effects under the studied conditions.
Is It Time to Reconsider Chronic Electromagnetic Field Exposure as a Possible Risk Factor in Oral Cancer?
This review/technical note discusses whether chronic EMF exposure, mainly from mobile phones and wireless devices, should be reconsidered as a possible risk factor for oral cancer/OSCC. It highlights biological plausibility and reports from pilot cytogenetic and laboratory studies, plus limited epidemiological observations, suggesting increased micronucleus formation and altered stress responses in buccal mucosal cells among long-term users. The authors emphasize that a direct causal link to OSCC is not established and call for more comprehensive research.
Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones
This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart, with malignant glioma of the brain also reported as related to exposure. In females, the report concludes equivocal evidence of carcinogenic activity for both modulations based on selected tumor outcomes, and genetic toxicology findings were mixed with some comet assay increases/equivocal results but negative micronucleus assays.
Genetic damage in mammalian somatic cells exposed to radiofrequency radiation: a meta-analysis of data from 63 publications (1990-2005)
A meta-analysis of 63 publications assessed whether radiofrequency (RF) radiation exposure is associated with genetic damage in mammalian somatic cells using multiple genotoxicity endpoints. Overall differences between RF-exposed and control conditions were reported as small, though statistically significant increases were observed for some endpoints under certain exposure conditions. Mean chromosomal aberration and micronucleus indices were reported to fall within historical spontaneous levels, and the analysis found considerable evidence of publication bias.