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Showing results for: Sprague Dawley

The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study

Research PubMed: RF-EMF health Jan 13, 2026

This PubMed-listed animal study reports results from the Japanese arm of an international Japan–Korea collaboration evaluating whether long-term mobile-phone-like RF-EMF exposure causes cancer or genetic damage in rats. Male Sprague Dawley rats were exposed to 900 MHz CDMA-modulated RF-EMF at a whole-body SAR of 4…

The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study

Research RF Safe Research Library Jan 1, 2026

This international collaborative animal study (Japanese arm) evaluated carcinogenicity and genotoxicity in male Sprague Dawley rats exposed long-term to 900 MHz CDMA-modulated RF-EMFs at 4 W/kg whole-body SAR. The abstract reports no statistically significant increases in neoplastic or non-neoplastic lesions in major…

Time-Dependence Effect of 2.45 GHz RF-EMR Exposure on Male Reproductive Hormones and LHCGR

Research RF Safe Research Library Jan 1, 2025

This animal study exposed male Sprague Dawley rats to 2.45 GHz Wi-Fi for varying daily durations over eight weeks and assessed reproductive hormones and LHCGR expression. Serum LH and testosterone did not differ significantly from controls, but LHCGR mRNA increased with longer exposure and LHCGR protein showed…

Characterization of the Core Temperature Response of Free-Moving Rats to 1.95 GHz Electromagnetic Fields

Research RF Safe Research Library Jan 1, 2025

This animal study measured core body temperature in free-moving male and female Sprague Dawley rats during and after 3-hour exposure to 1.95 GHz RF-EMF at multiple whole-body average SAR levels. A measurable thermal response was reported at 4 W/kg, while lower SAR conditions showed smaller or no significant…

The effect on rat peripheral nerve morphology and function of a 900-MHz electromagnetic field applied in the prenatal period

Research RF Safe Research Library Jan 1, 2025

This animal study exposed pregnant Sprague Dawley rats to a 900 MHz electromagnetic field for 1 hour daily throughout gestation and assessed offspring outcomes postnatally. Sciatic nerve analyses at postnatal day 60 indicated persistent morphological alterations attributed to prenatal EMF exposure. However, the…

Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones

Research RF Safe Research Library Jan 1, 2018

This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart,…

Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats

Research RF Safe Research Library Mar 1, 2017

This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following…

The effects of radio-frequency electromagnetic fields on T cell function during development

Research RF Safe Research Library Jan 1, 2015

This animal study exposed developing Sprague Dawley rats to 2.14 GHz W-CDMA RF-EMF at a whole-body SAR of 0.2 W/kg for 9 weeks (20 h/day). No differences were reported in multiple T cell population measures across blood, spleen, and thymus. Some Th1/Th2-related genes were upregulated (notably in thymus), but serum…

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