In-Depth Analysis of Chlorophyll Fluorescence Rise Kinetics Reveals Interference Effects of a Radiofrequency Electromagnetic Field (RF-EMF) on Plant Hormetic Responses to Drought Stress.
Research
RF Safe Research Library
Jan 1, 2025
This experimental study assessed chlorophyll fluorescence rise kinetics in lettuce plants exposed to RF-EMFs and subjected to a short drought treatment. Using a conventional JIP test and a machine learning-assisted anomaly-detection approach, the authors report that RF-EMF exposure weakened drought-induced hormetic…
Effects of radiofrequency electromagnetic fields on cognitive function in elderly subjects (60+ years)-Results of an experimental randomized sham controlled double-blind cross-over study in women and in men.
Research
RF Safe Research Library
Jan 1, 2025
This double-blind randomized sham-controlled cross-over study tested short-term RF-EMF exposure effects on cognitive performance in 60 healthy adults aged 60–80 years. Participants completed attentional tasks during exposure to GSM 900 MHz, TETRA 385 MHz, or sham across nine sessions. Two of 16 outcomes showed…
Prophylactic Effects of Radiofrequency Electromagnetic Field on Pulmonary Ischemia-Reperfusion via HIF-1α/eNOS Pathway and BCL2/BAX Signaling.
Research
RF Safe Research Library
Jan 1, 2025
This animal study tested whether RF-EMF exposure modifies lung ischemia-reperfusion injury in male Wistar rats. IR increased histologic injury, inflammatory/apoptotic markers, oxidative stress indices, and Hif-1α/eNOS/BAX while decreasing BCL2. The IR + RF-EMF group reportedly improved across measured parameters, and…
Corrigendum to "Effects of radiofrequency electromagnetic field (RF-EMF) exposure on male fertility: A systematic review of experimental studies on non-human mammals and human sperm in vitro" [Environ. Int. 185 (2024) 108509]
Research
RF Safe Research Library
Jan 1, 2025
This 2025 corrigendum relates to a systematic review of experimental RF-EMF exposure studies on non-human mammals and human sperm in vitro. The text reports an upgrade to high certainty for the key endpoint that male RF-EMF exposure causes a significant reduction in pregnancy rate when exposed males are mated. It…
Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review
Research
RF Safe Research Library
Jan 1, 2025
This systematic review evaluated RF-EMF exposure and cancer outcomes in experimental animals, including 52 studies (20 chronic cancer bioassays), using narrative synthesis due to substantial heterogeneity. The review reports no or minimal evidence of RF-EMF-related cancer outcomes for many organ systems, but reports…
Mitigating Heat-Induced Sperm Damage and Testicular Tissue Abnormalities: The Protective Role of Radiofrequency Radiation from Wi-Fi Routers in Rodent Models
Research
RF Safe Research Library
Jan 1, 2024
This rodent study examined whether 2.45 GHz Wi‑Fi router RF-EMF exposure could mitigate heat-stress-related reproductive damage in male rats. The combined RF-EMF + heat group reportedly had improved testicular structure measures and sperm quality versus heat-only, while RF-EMF alone was also reported to alter testis…
Evaluation of the Thyroids of Offsprings Exposed to 2450 MHz Radiofrequency Radiation During Pregnancy: A Sixth Month Data
Research
RF Safe Research Library
Jan 1, 2024
This animal study examined whether continuous prenatal exposure to 2450 MHz radiofrequency radiation (simulating Wi‑Fi) affects thyroid tissue in rat offspring at 6 months. The exposed group showed significantly increased mononuclear cell infiltration and vascular congestion in thyroid histology. TUNEL-positive cell…
Relationship between radiofrequency-electromagnetic radiation from cellular phones and brain tumor: meta-analyses using various proxies for RF-EMR exposure-outcome assessment
Research
RF Safe Research Library
Jan 1, 2024
Moon et al. (2024) report a systematic review and meta-analysis on cellular phone RF-EMR and brain tumor risk. The abstract summary states elevated risks for three brain tumor types in analyses considering ipsilateral (same-side) phone use and reports increased risk with heavy and long-term use. The text also…
The effects of radiofrequency exposure on male fertility: A systematic review of human observational studies with dose-response meta-analysis (SR 3)
Research
RF Safe Research Library
Jan 1, 2024
This systematic review and dose-response meta-analysis synthesizes human observational studies on radiofrequency EMF exposure and male fertility outcomes. It reports evidence of an association between RF exposure and poorer sperm parameters, including reduced quality, motility, and viability. The authors frame the…
Effects of radiofrequency field from 5G communication on fecal microbiome and metabolome profiles in mice
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed adult male C57BL/6 mice to a 4.9 GHz radiofrequency field for three weeks (1 hour/day) and compared them with a sham group. The abstract reports altered fecal microbiome composition with reduced diversity in the RF group, along with 258 significantly differentially abundant fecal…
Transcriptional response of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed rat primary hippocampal neurons to 3.0 GHz continuous-wave RF-EMF under low-SAR (minimal heating) and high-SAR (thermal) conditions and measured transcriptional responses by RNA sequencing. Twenty genes were significantly upregulated only in the high-SAR condition associated with a ~3.6°C…
Comparison of a radiofrequency electric and magnetic field source-based job-exposure matrix with personal radiofrequency exposure measurements.
Research
RF Safe Research Library
Jan 1, 2024
This study compared historical occupational RF-EMF exposure estimates from the INTEROCC RF job-exposure matrix (RF-JEM) with recent personal RF-EMF measurements from the OccRF-Health study in two countries. Agreement between the two approaches was poor for both exposure prevalence and 8-hour time-weighted average…
Investigating the effect of radiofrequency electromagnetic field exposure on molecular pathways related to insulin resistance and adipogenesis in zebrafish embryos - A pilot study without quantitative exposure metrics.
Research
RF Safe Research Library
Jan 1, 2024
This pilot animal study exposed zebrafish embryos to 900 MHz RF-EMF for 30 or 60 minutes per day until 96 hours post-fertilization and assessed gene expression and physiological endpoints. The authors report reduced expression of lepa, ins, and pparg, changes in oxidative stress markers consistent with increased…
Exposure to Radiofrequency Induces Synaptic Dysfunction in Cortical Neurons Causing Learning and Memory Alteration in Early Postnatal Mice.
Research
RF Safe Research Library
Jan 1, 2024
This animal study examined 1850 MHz RF-EMF exposure (SAR 4.0 W/kg) in early postnatal mice and assessed synaptic and behavioral outcomes. The abstract reports reductions in dendritic spine maturation markers, decreases in PSD-95 puncta, inhibited neurite outgrowth, and downregulation of synapse-related genes in…
Anthropogenic electromagnetic radiation alters the transcription levels of the genes encoding the SIFamide and myoinhibitory peptide and their receptors in Ixodes ricinus synganglion.
Research
RF Safe Research Library
Jan 1, 2024
This animal study used qRT-PCR to assess whether 900 MHz radiofrequency electromagnetic field exposure alters neuropeptide-related gene transcription in Ixodes ricinus synganglia. The abstract reports that 40 V/m exposure for at least 60 minutes significantly suppressed transcript levels of sifa, mip, and their…
Improved assessment of radiofrequency electromagnetic field power deposition near orthopaedic device using a bone-inclusive ASTM phantom under 1.5T and 3T MRI.
Research
RF Safe Research Library
Jan 1, 2024
This engineering/simulation study proposes a bone-inclusive ASTM phantom to improve assessment of RF power deposition near orthopaedic implants during 1.5 T and 3 T MRI. Using numerical simulations across multiple implant families, the authors report better correlation of peak 1 g SAR near implants with anatomically…
Effects of 2.4 GHz radiofrequency electromagnetic field (RF-EMF) on glioblastoma cells (U -118 MG).
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed glioblastoma (U-118 MG) and human embryonic kidney (Hek-293) cells to 2.4 GHz RF-EMF for 24–72 hours, with or without a dielectric screen. The authors report a significant decrease in cell viability after exposure in both cell lines. The decrease was described as greater in glioblastoma…
Personal exposure to radiofrequency electromagnetic fields in various occupations in Spain and France.
Research
RF Safe Research Library
Jan 1, 2023
This study conducted personal full-shift RF-EMF measurements in 333 workers across 46 occupations in Spain and France. Most 1-second measurements of electric and magnetic fields were below the device detection limit (≥1% of 1998 ICNIRP standards), though many workers had at least one detectable reading. A small…
A Novel and Versatile Microfluidic Device for Cell Assays under Radio Frequency Exposure.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study describes a microfluidic device integrated with a radiofrequency exposure system to enable on-chip monitoring of cellular responses under a 1.8 GHz field. Using human amniotic epithelial cells, the authors report field-intensity-associated increases in protrusions/filopodia, changes in…
Low-energy amplitude-modulated radiofrequency electromagnetic fields as a systemic treatment for cancer: Review and proposed mechanisms of action
Research
RF Safe Research Library
Sep 8, 2022
This review discusses low-energy amplitude-modulated RF EMF (27.12 MHz carrier with low Hz–kHz envelope modulation) delivered systemically via intrabuccal antenna devices as a potential treatment for advanced hepatocellular carcinoma. It reports preclinical inhibition of cancer growth in vitro and in mouse xenograft…
Evidences of the (400 MHz - 3 GHz) radiofrequency electromagnetic field influence on brain tumor induction.
Research
RF Safe Research Library
Jan 1, 2022
This review discusses whether radiofrequency electromagnetic fields (400 MHz–3 GHz), particularly from mobile phones, influence brain tumor induction. The abstract describes epidemiological evidence as supporting a causal association, highlighting statistically significant ipsilateral tumor findings. It also claims…
The effect of long-term radiofrequency exposure on cognition in human observational studies: A protocol for a systematic review.
Research
RF Safe Research Library
Jan 1, 2022
This paper presents a protocol for a systematic review of human observational studies assessing long-term radiofrequency (100 kHz to 300 GHz) EMF exposure and cognitive outcomes. It plans to include cohort and case-control studies with at least 6 months follow-up and validated cognitive measures, and to evaluate…
PIXE analysis of iron in rabbit cerebellum after exposure to radiofrequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2022
This animal study assessed iron in rabbit cerebellum after exposure to real GSM and generated RF electromagnetic fields using ICP MS and PIXE. ICP MS found no significant differences in overall iron concentration between exposed and control groups. PIXE reported focal iron accumulation up to about 3 mm, with the…
Evaluation of Cell Migration and Cytokines Expression Changes under the Radiofrequency Electromagnetic Field on Wound Healing In Vitro Model.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study evaluated whether radiofrequency electromagnetic field (RF-EMF) exposure could influence wound-healing-related processes. The authors report increased keratinocyte migration and changes in expression of wound-healing genes, including MMPs, TIMPs, and pro/anti-inflammatory cytokines. The abstract…
Prioritizing health outcomes when assessing the effects of exposure to radiofrequency electromagnetic fields: A survey among experts.
Research
RF Safe Research Library
Jan 1, 2021
This paper reports a survey designed to prioritize which RF EMF-related health outcomes should be addressed in systematic reviews. Of 300 experts queried, 164 responded and rated cancer, heat-related effects, adverse birth/pregnancy outcomes, electromagnetic hypersensitivity, cognitive impairment, and oxidative…