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A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses biological mechanisms and reported health effects of anthropogenic extremely low frequency (ELF) and wireless communication (WC) electromagnetic fields. It highlights oxidative stress and DNA damage as key mechanistic endpoints and proposes an IFO-VGIC pathway linking EMF exposure to…

Skin Fibroblasts from Individuals Self-Diagnosed as Electrosensitive Reveal Two Distinct Subsets with Delayed Nucleoshuttling of the ATM Protein in Common

Research RF Safe Research Library Jan 1, 2025

This study reports on 26 adults self-diagnosed with electromagnetic hypersensitivity (EHS) who provided skin biopsies to generate primary fibroblast lines. The authors describe two EHS subsets based on questionnaire and DNA damage-related measures, and report delayed ATM nucleoshuttling after X-ray exposure in all…

Exploring the impact of environmental factors on male reproductive health through epigenetics

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses how environmental factors may affect male reproductive health through epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation. It reports that electromagnetic radiation, particularly from mobile phones and wireless…

Potential Impacts of Radiofrequency Electromagnetic Fields on the Central Nervous System, Brain Neurotransmitter Dynamics and Reproductive System

Research RF Safe Research Library Jan 1, 2025

This review discusses potential impacts of radiofrequency electromagnetic fields from technologies such as Wi‑Fi and mobile phones on the central nervous system, neurotransmitter dynamics, and reproductive health. It describes proposed mechanisms including oxidative stress, thermal effects, altered neurotransmitter…

Melatonin ameliorates RF-EMR-induced reproductive damage by inhibiting ferroptosis through Nrf2 pathway activation

Research RF Safe Research Library Jan 1, 2025

This animal study reports that prolonged RF-EMR exposure (2.45 GHz for 8 weeks) increased oxidative stress and ferroptosis in mouse testicular tissue and was associated with reduced sperm quality. Melatonin administration reportedly mitigated oxidative injury and inhibited ferroptosis. The abstract attributes the…

Effects of 700MHz radiofrequency radiation (5G lower band) on the reproductive parameters of female Wistar rats

Research RF Safe Research Library Jan 1, 2025

This animal study examined short- and long-term 700 MHz (lower-band 5G) radiofrequency exposure in female Wistar rats, comparing control, sham, and exposed groups. It reports no DNA damage and no change in estrous cycle length, but increased ovarian oxidative stress markers in exposed animals. Long-term exposure was…

The effects of radiofrequency radiation on male reproductive health and potential mechanisms (Review)

Research RF Safe Research Library Jan 1, 2025

This narrative review summarizes human and animal research on radiofrequency (RF) radiation exposure (e.g., mobile phones, Wi‑Fi, occupational sources) and male reproductive outcomes. It reports that the literature links RF exposure with reduced sperm quality and increased DNA damage, often alongside oxidative stress…

Effect of ELF-EMF on cognitive functions, analgesia, and oxidative stress in rats with PTZ-induced epilepsy.

Research RF Safe Research Library Jan 1, 2025

This animal study tested repeated 50 Hz, 5 mT ELF-EMF exposure in rats with and without PTZ-induced epilepsy. The authors report changes in learning/short-term memory in the EMF+PTZ group versus PTZ alone and increased analgesia latency in EMF-exposed groups. PTZ increased oxidative stress (TOS) in brain regions, and…

Effect of 900 MHz Electromagnetic Field Exposure During Different Trimesters of Pregnancy on TRPM2-Mediated Ferroptosis and Neurotoxicity in the Trigeminal Ganglion of Rats: Protective Role of Ferrostatin-1.

Research RF Safe Research Library Jan 1, 2025

This animal study examined prenatal 900 MHz EMF exposure during different pregnancy trimesters and measured oxidative stress, inflammatory, apoptotic, and TRPM2-related markers in rat offspring trigeminal ganglia at postnatal day 28. The abstract reports increased oxidative stress/lipid peroxidation, inflammation,…

Possible effects of melatonin and omega-3 on the obesity-related hypothalamic nuclei of the electromagnetic field-exposed offspring rats: a stereological and immunohistochemical analysis.

Research RF Safe Research Library Jan 1, 2025

This animal study examined whether prenatal exposure to a 900 MHz electromagnetic field affects obesity-related hypothalamic nuclei in male rat offspring and whether melatonin or omega-3 modifies these effects. The EMF-exposed group showed fewer neurons in the arcuate nucleus, stronger NPY immunoreactivity, and…

Role of radio-frequency electromagnetic waves in causing oxidative stress

Research RF Safe Research Library Jan 1, 2024

This animal study exposed fertilized chick eggs to a nearby 1800 MHz mobile phone that was called repeatedly (50 minutes/day) and assessed embryos at days 10 and 15. The exposed group reportedly showed mitochondrial abnormalities in liver, brain, and heart tissues on electron microscopy, along with increased HSP70 in…

A Pilot Study Evaluating the Feasibility and Efficacy of an In-Home Resonance-Based Electromagnetic Field Protection Device on Improving Markers of Health and Cognitive Function Among a Sample of Healthy Adults.

Research RF Safe Research Library Jan 1, 2024

This single-arm 12-week pilot/feasibility study enrolled 25 relatively healthy adults to evaluate an in-home resonance-based EMF protection device (BluShield). The abstract reports high compliance and no adverse events, with modest improvements in self-reported health, several cognitive questionnaire domains, and…

Impact of Extremely Low-Frequency Electromagnetic Fields on Skeletal Muscle of Sedentary Adult Mice: A Pilot Study.

Research RF Safe Research Library Jan 1, 2024

This pilot animal study examined ELF-EMF exposure (0.1 or 1.0 mT, 1 h/day up to 5 weeks) in sedentary adult male C57BL/6 mice, with or without N-acetyl-cysteine (NAC) supplementation. The authors report a transient increase in muscle strength after 2 weeks at 1.0 mT, accompanied by higher PAX7 and myosin heavy chain…

Investigating the effect of radiofrequency electromagnetic field exposure on molecular pathways related to insulin resistance and adipogenesis in zebrafish embryos - A pilot study without quantitative exposure metrics.

Research RF Safe Research Library Jan 1, 2024

This pilot animal study exposed zebrafish embryos to 900 MHz RF-EMF for 30 or 60 minutes per day until 96 hours post-fertilization and assessed gene expression and physiological endpoints. The authors report reduced expression of lepa, ins, and pparg, changes in oxidative stress markers consistent with increased…

The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional…

Transcriptomic Analysis of Gene Expression and Effect of Electromagnetic Field in Brain Tissue after Traumatic Brain Injury.

Research RF Safe Research Library Jan 1, 2024

This pilot animal study used a Yucatan miniswine model of traumatic brain injury with and without EMF stimulation to examine differential gene expression in injured versus non-injured cortex tissue. The authors report multiple differentially expressed genes linked to immune infiltration, myelination, oxidative stress…

Comparison of pulsed and continuous electromagnetic field generated by WPT system on human dermal and neural cells.

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested electromagnetic fields generated by a prototype wireless power transfer (wireless charging) system on four human dermal and neural cell lines. Across pulsed and continuous exposure conditions, the authors report no negative effects on morphology/cytoskeleton, viability/mitosis,…

Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells

Research RF Safe Research Library Nov 7, 2023

This in vitro study characterized spinning oscillating magnetic field (sOMF) stimulation patterns that the authors report can induce cytotoxicity in two types of human glioma cells. The reported effect was linked to a critical rise in superoxide, and was reversed by the antioxidant Trolox, suggesting ROS involvement.…

Effects of prenatal mobile phone radiation exposure on MMP9 expression: Implications for inflammation, oxidative stress, and sensory-motor impairment after neonatal hypoxia- ischemia in rats

Research RF Safe Research Library Oct 13, 2023

This animal study examined whether prenatal mobile phone RF exposure affects brain injury markers and outcomes after neonatal hypoxia-ischemia in rats. The HI/Exposure group showed higher MMP-9 expression along with increased inflammatory and oxidative stress markers, larger infarct volume and edema, and worse…

Lipoic acid inhibits cognitive impairment induced by multiple cell phones in young male rats: role of Sirt1 and Atg7 pathway.

Research RF Safe Research Library Jan 1, 2023

This animal study examined whether lipoic acid modifies cognitive and hippocampal effects in young male rats exposed to EMF emitted from multiple cell phones. The authors report improved learning performance but impaired long-term memory consolidation after EMF exposure, alongside changes in hippocampal…

Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue.

Research RF Safe Research Library Jan 1, 2023

This experimental mouse study tested whether N-acetylcysteine (NAC), pulsed electromagnetic fields (PEMF), or their combination improves outcomes after transplantation of vitrified ovarian tissue. The abstract reports increased follicle numbers and enhanced vascularization in NAC, PEMF, and NAC+PEMF groups, along…

Transcriptome profiling of flax plants exposed to a low-frequency alternating electromagnetic field.

Research RF Safe Research Library Jan 1, 2023

This study aims to perform transcriptome profiling in flax plants exposed to a low-frequency alternating electromagnetic field. The abstract frames prior work as suggesting EMF-related changes in free radical homeostasis and altered expression of genes involved in stress responses, ion transport, and cell wall…

Ameliorative effects of crocin against electromagnetic field-induced oxidative stress and liver and kidney injuries in mice.

Research RF Safe Research Library Jan 1, 2023

This mouse experiment evaluated whether crocin (50 mg/kg) mitigates liver and kidney injury associated with 2100 MHz electromagnetic field exposure. EMF exposure was associated with increased serum markers of kidney and liver injury, reduced antioxidant enzyme activity, and histopathological/ultrastructural changes…

Electromagnetic fields ameliorate hepatic lipid accumulation and oxidative stress: potential role of CaMKKβ/AMPK/SREBP-1c and Nrf2 pathways.

Research RF Safe Research Library Jan 1, 2023

This animal study examined EMF exposure in a mouse high-fat diet model of NAFLD. The authors report that EMF exposure reduced hepatic lipid accumulation and markers of oxidative stress, alongside changes consistent with activation of CaMKKβ/AMPK and Nrf2-related signaling. The abstract concludes EMF could be a…

Effect of extremely low frequency electromagnetic field on the pathogenicity of Magnaporthe oryzae.

Research RF Safe Research Library Jan 1, 2023

This laboratory study examined Magnaporthe oryzae pathogenicity under extremely low frequency electromagnetic field exposure (50 Hz, 3 mT). The authors report increased infection ability, growth rate, and conidia generation with ELF-EMF exposure. They also report increased tolerance to a cell wall-perturbing agent…

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