Effects of extremely low-frequency electromagnetic field exposure on the skeletal muscle functions in rats.
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RF Safe Research Library
Jan 1, 2020
This rat study examined chronic extremely low-frequency electromagnetic field (ELF-EMF) exposure and diaphragm muscle function and structure. Rats were exposed to 50 Hz, 1.5 mT for 4 hours daily for up to 7 months and assessed with electrophysiological, biochemical, and electron-microscopy measures. The authors…
Antimicrobial activity of rosemary leaf extracts and efficacy of ethanol extract against testicular damage caused by 50-Hz electromagnetic field in albino rats.
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Jan 1, 2020
This animal study exposed male albino rats to a 50 Hz electromagnetic field for 2 or 4 hours and assessed reproductive hormones, oxidative stress markers, and testicular histology after 30 days. The abstract reports that EMF exposure reduced serum FSH, testosterone, and LH and catalase activity, while increasing…
Electromagnetic field treatment increases purinergic receptor P2X7 expression and activates its downstream Akt/GSK3β/β-catenin axis in mesenchymal stem cells under osteogenic induction.
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Jan 1, 2019
This study examined how electromagnetic field (EMF) treatment influences osteogenic differentiation mechanisms in human bone marrow mesenchymal stem cells and tested a combined therapy in an ovariectomized rat osteoporosis model. The authors report that EMF exposure increased P2X7 receptor expression during…
The specific absorption rate in different brain regions of rats exposed to electromagnetic plane waves.
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Jan 1, 2019
This study develops a numerical voxel rat model with 10 segmented brain regions to evaluate region-specific dosimetry under plane-wave EMF exposure. It reports that brain-region averaged SAR varies with frequency, incidence direction, and E-polarization direction. The authors also report potentially large deviations…
Effects of 5-HT and 5-HT Receptor Agonists on Electromagnetic Field-Induced Analgesia in Rats.
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Jan 1, 2019
This animal study examined whether serotonergic signaling modifies analgesia associated with repeated ELF electromagnetic field exposure. Sixty-six male Wistar rats were exposed to 50 Hz, 5 mT for 2 hours/day over 15 days and then received 5-HT agonists or antagonists before analgesia testing. Agonists increased,…
Altered morphology and biochemistry of the female rat liver following 900 megahertz electromagnetic field exposure during mid to late adolescence.
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Jan 1, 2019
This animal study examined whether 900 MHz EMF exposure during mid to late adolescence affects the liver in female rats. Compared with control and sham groups, the exposed group showed occasional liver histopathological irregularities. The exposed group also had significantly decreased 8-OHdG and SOD levels, and the…
Effect of Modified Wuzi Yanzong Pill () on Tip60-Mediated Apoptosis in Testis of Male Rats after Microwave Radiation.
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Jan 1, 2019
This animal study exposed male rats to a single 15-minute microwave radiation session and assessed testicular apoptosis, histopathology, and related proteins. The radiation group showed increased apoptosis and testicular structural alterations versus controls at multiple time points, while a modified Wuzi Yanzong…
Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones
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Jan 1, 2018
This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart,…
Electromagnetic Fields of Mobile Phone Jammer Exposure on Blood Factors in Rats.
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Jan 1, 2018
This rat study examined whether electromagnetic fields from a mobile phone jammer affect blood cell factors. Rats were exposed 8 hours/day, 5 days/week for 40 days and compared with control and sham groups. The authors report significant changes in multiple hematological indices, with some measures unchanged…
The legacy effects of electromagnetic fields on bone marrow mesenchymal stem cell self-renewal and multiple differentiation potential.
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Jan 1, 2018
This animal study examined whether electromagnetic field (EMF) pretreatment has lasting (“legacy”) effects on rat bone marrow mesenchymal stem cells (BMSCs) and whether EMF-pretreated BMSC sheets improve fracture nonunion healing in rats. The authors report increased BMSC proliferation and enhanced…
Effects of 900-MHz electromagnetic fields exposure throughout middle/late adolescence on the kidney morphology and biochemistry of the female rat.
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Jan 1, 2018
This animal study examined kidney effects in female rats exposed to continuous 900 MHz EMF for 1 hour daily during postnatal days 35–59. The authors report multiple histopathological alterations in kidneys of the EMF-exposed group, while control and sham groups showed no pathology. TOS and OSI were reported to be…
Effect of Microwave Wi-Fi Radiation at Frequency of 2.4 GHz on Epileptic Behavior of Rats.
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Jan 1, 2018
This animal study exposed rats to 2.4 GHz Wi-Fi radiation for 2 hours at 30 cm from a commercial router and assessed PTZ-induced convulsive behavior. The Wi-Fi "on" PTZ group showed significant differences in seizure event counts and summed severity scores versus comparison groups, while several timing and duration…
A Single Exposure to GSM-1800 MHz Signals in the Course of an Acute Neuroinflammatory Reaction can Alter Neuronal Responses and Microglial Morphology in the Rat Primary Auditory Cortex.
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Jan 1, 2018
This animal study examined whether acute GSM-1800 MHz exposure affects the auditory cortex during experimentally induced neuroinflammation. In LPS-treated rats, a single 2-hour head-only exposure (average SAR 1.55 W/kg in auditory cortex) was associated with altered microglial morphology and reduced neuronal activity…
Effect of Electromagnetic Waves from Mobile Phones on Spermatogenesis in the Era of 4G-LTE.
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Jan 1, 2018
This animal experiment assessed whether long-duration 4G-LTE mobile phone electromagnetic field exposure affects spermatogenesis in male rats. After 1 month, the highest exposure condition (3 cm distance, 18 h/day) had reduced spermatid, spermatogonia, total germ cell, and Leydig cell counts compared with sham and…
Continuous 900-megahertz electromagnetic field applied in middle and late-adolescence causes qualitative and quantitative changes in the ovarian morphology, tissue and blood biochemistry of the rat.
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Jan 1, 2018
This animal study exposed adolescent female rats to a 900-MHz electromagnetic field for 1 hour per day from postnatal days 35 to 59 and assessed ovarian histology and biochemical markers. The EMF group showed multiple histopathological changes in ovarian tissue and had fewer secondary follicles than the other groups.…
Microwave radiation leading to shrinkage of dendritic spines in hippocampal neurons mediated by SNK-SPAR pathway.
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Jan 1, 2018
This animal study exposed Wistar rats to microwave radiation (30 mW/cm for 6 minutes, three times per week for six weeks) and assessed cognition, hippocampal dendritic spines, ultrastructure, and SNK-SPAR pathway molecules. The authors report impaired spatial learning and memory, dendritic spine loss/shrinkage, and…
Autophagy mediates the degradation of synaptic vesicles: A potential mechanism of synaptic plasticity injury induced by microwave exposure in rats.
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RF Safe Research Library
Jan 1, 2018
This animal study used an in vivo microwave exposure model (30 mW/cm) and reports reversible neuronal injuries in rats. The authors observed cognitive impairment and synaptic plasticity injury in hippocampal neurons following exposure. Autophagy was activated, and autophagosomes showed increased association with…
Age-dependent effect of long-term microwave radiation on postnatal neurogenesis in rats: morphological and behavioral study.
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Jan 1, 2018
This animal study examined pulsed-wave 2.45 GHz microwave radiation exposure (1 or 3 hours daily for 3 weeks) in adult and juvenile rats and assessed neurogenesis-related markers in the rostral migratory stream. The authors report reduced cell proliferation in adults and longer-lasting effects on cell death after…
NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595
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Jan 1, 2018
This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…
Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats
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Mar 1, 2017
This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following…
Effects of electromagnetic fields on bone loss in hyperthyroidism rat model.
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Jan 1, 2017
This animal study evaluated whether extremely low frequency EMF exposure affects bone loss in a levothyroxine-induced hyperthyroidism rat model. Rats exposed to 15 Hz/1 mT EMF plus levothyroxine showed improved bone mineral density, mechanical measures, and partially restored trabecular bone architecture compared…
No adverse effects detected for simultaneous whole-body exposure to multiple-frequency radiofrequency electromagnetic fields for rats in the intrauterine and pre- and post-weaning periods.
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Jan 1, 2017
This animal study exposed pregnant Sprague-Dawley rats and their offspring to simultaneous whole-body multifrequency RF signals spanning 800 MHz to 5.2 GHz. Exposure occurred 20 hours per day from gestational day 7 to weaning, with F1 offspring exposed up to 6 weeks of age. Across multiple endpoints including growth,…
Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields.
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Jan 1, 2017
This rat study examined 900 MHz EMF exposure for 60 minutes per day over 15 days and assessed hippocampal and cerebellar outcomes, behavior, and serum enzyme activity. The EMF-only group showed significant neuronal cell losses in multiple brain regions and worse passive avoidance performance compared with other…
Does omega-3 have a protective effect on the rat adrenal gland exposed to 900 MHz electromagnetic fields?
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RF Safe Research Library
Jan 1, 2017
This animal study examined whether omega-3 modifies adrenal gland changes in rats exposed to 900 MHz electromagnetic fields. Rats exposed 60 minutes/day for 15 days showed significantly increased adrenal gland volume versus controls. Omega-3 co-treatment was associated with significantly lower adrenal gland volume…
Effects of extremely low frequency electromagnetic fields on morphine analgesia and tolerance in rats.
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RF Safe Research Library
Jan 1, 2017
This animal study examined whether extremely low frequency electromagnetic field exposure alters morphine analgesia and tolerance in rats. Rats exposed to a 50 Hz magnetic field (reported as 5 mT) showed higher morphine analgesic effects than rats given morphine without field exposure. In morphine-tolerant rats,…