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Early exposure to radiofrequency electromagnetic fields at 1850 MHz affects auditory circuits in early postnatal mice.

Research RF Safe Research Library Jan 1, 2019

This animal study examined early postnatal mice after exposure to 1850 MHz RF-EMF and measured synaptic activity in brainstem auditory circuitry. The abstract reports increased spontaneous postsynaptic current frequency and amplitude in MNTB principal cells, with accompanying presynaptic changes in the calyx of Held…

Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones

Research RF Safe Research Library Jan 1, 2018

This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart,…

Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice.

Research RF Safe Research Library Jan 1, 2018

This animal study exposed 14-month-old C57BL/6 mice to 1950 MHz RF-EMF (SAR 5 W/kg) for 8 months. The authors report that aging was associated with increased oxidative damage, DNA damage, apoptosis, and glial activation markers in brain tissue. Long-term RF-EMF exposure did not change these markers in aged mice and…

Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields.

Research RF Safe Research Library Jan 1, 2018

This study reports the identification of an electromagnetic perceptive gene (EPG) from glass catfish and its expression in mammalian cells, neuronal cultures, and rat brain. The authors report that magnetic/EMF stimulation remotely increased intracellular calcium in EPG-expressing cells and neurons. They also report…

NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595

Research RF Safe Research Library Jan 1, 2018

This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…

Effect of extremely low frequency electromagnetic field on brain histopathology of Caspian Sea Cyprinus carpio.

Research RF Safe Research Library Jan 1, 2017

This animal study evaluated 50 Hz extremely low frequency electromagnetic field exposure and brain histopathology in Cyprinus carpio. Fish were sham-exposed or exposed to magnetic field intensities from 0.1 to 7 mT for 0.5 or 1 hour. The authors report severe brain histopathological changes at intensities ≥3 mT,…

Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields.

Research RF Safe Research Library Jan 1, 2017

This rat study examined 900 MHz EMF exposure for 60 minutes per day over 15 days and assessed hippocampal and cerebellar outcomes, behavior, and serum enzyme activity. The EMF-only group showed significant neuronal cell losses in multiple brain regions and worse passive avoidance performance compared with other…

Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation.

Research RF Safe Research Library Jan 1, 2017

This study assessed whether adding extremely low-frequency electromagnetic field (ELF-EMF) exposure to a 4-week poststroke rehabilitation program affects nitric oxide (NO)-related biomarkers and patient status. Forty-eight poststroke patients were assigned to ELF-EMF versus non-ELF-EMF rehabilitation, with the…

Comments on "Radiofrequency electromagnetic fields and some cancers of unknown etiology: An ecological study".

Research RF Safe Research Library Jan 1, 2017

This correspondence discusses a prior ecological study examining a possible association between RF-EMF exposure in Albacete, Spain and cancer incidence. The cancers mentioned include lymphomas and brain tumors. The correspondence indicates that shortcomings of the ecological study are discussed, but does not detail…

Radiofrequency electromagnetic fields and some cancers of unknown etiology: An ecological study.

Research RF Safe Research Library Jan 1, 2017

This preliminary ecological study examined whether RF-EMF exposure in Albacete (Spain) correlated with incidence of lymphomas and brain tumors from January 2012 to May 2015. Personal RF-EMF exposure was measured across 14 frequency bands using an EME Spy 140 exposimeter and compared with tumor incidence by…

The influence of prenatal 10 GHz microwave radiation exposure on a developing mice brain.

Research RF Safe Research Library Jan 1, 2017

This animal study examined prenatal exposure to 10 GHz microwave radiation starting at gestation day 0.25 or 11.25 until term. At 3 weeks of age, offspring from exposed pregnancies showed reduced brain and body weight and biochemical changes consistent with oxidative stress compared with sham controls. The authors…

Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats.

Research RF Safe Research Library Jan 1, 2017

This animal study examined whole-body exposure to 2.45 GHz microwave radiation for 2 h/day over 35 days in male Wistar rats. The authors report increased lipid peroxidation (LPO) in liver, brain, and spleen and histological changes across multiple organs compared with sham-exposed controls. They conclude the exposure…

Effects of GSM modulated radio-frequency electromagnetic radiation on permeability of blood-brain barrier in male & female rats

Research RF Safe Research Library Jan 1, 2016

This rat study examined whether pulse-modulated 900 MHz and 1800 MHz RF exposure affects blood-brain barrier permeability using Evans blue dye. The abstract reports increased permeability in male rats at both frequencies (stronger at 1800 MHz) and in female rats at 900 MHz but not at 1800 MHz. The authors suggest…

Evaluation of the electric field in the brain during transcranial direct current stimulation: A sensitivity analysis.

Research RF Safe Research Library Jan 1, 2016

This computational study used finite element modeling to estimate the electric field distribution in the brain during tDCS for two electrode montages targeting the left DLPFC. It systematically varied isotropic tissue conductivity profiles to assess sensitivity of predicted E-field magnitude and components in the…

Disordered redox metabolism of brain cells in rats exposed to low doses of ionizing radiation or UHF electromagnetic radiation.

Research RF Safe Research Library Jan 1, 2016

This animal study assessed redox-state changes in rat brain cells after long-term low-intensity ionizing radiation exposure or fractionated non-thermal UHF electromagnetic radiation. Both exposures were associated with decreased ubisemiquinone and increased NO-FeS-protein complexes, alongside increased mitochondrial…

Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats

Research RF Safe Research Library Mar 19, 2015

This animal study exposed 108 male Sprague-Dawley rats to 900 MHz EMF (1 mW/cm2) or sham for 14 or 28 days (3 h/day). The authors report that 28-day exposure was associated with impaired spatial memory, BBB permeability damage, and ultrastructural changes in hippocampus and cortex. They also report increased mkp-1…

Effects of microwave radiation on brain energy metabolism and related mechanisms

Research RF Safe Research Library Feb 17, 2015

This paper is a narrative review of microwave radiation and brain energy metabolism. The abstract frames the brain as a sensitive target organ and highlights mitochondrial injury and energy metabolism disorders as important in microwave radiation-induced brain damage. It aims to summarize biological effects, brain…

Memory performance, wireless communication and exposure to radiofrequency electromagnetic fields: A prospective cohort study in adolescents

Research RF Safe Research Library Jan 1, 2015

This prospective cohort study followed 439 adolescents for one year to assess whether wireless device use and estimated RF-EMF dose were associated with changes in memory performance. Higher cumulative mobile phone call duration and higher modeled RF-EMF brain and whole-body dose were associated with decreases in…

Influence of electromagnetic field (1800 MHz) on lipid peroxidation in brain, blood, liver and kidney in rats

Research RF Safe Research Library Jan 1, 2015

This animal study evaluated repeated 1800 MHz EMF exposure (5 × 15 minutes) on lipid peroxidation (MDA) in Wistar rats, including healthy animals and those with CFA-induced inflammation, with and without tramadol. The authors report slightly elevated MDA in blood, brain, and kidneys in EMF-exposed conditions,…

Effect Of Electromagnetic Waves Emitted From Mobile Phone On Brain Stem Auditory Evoked Potential In Adult Males.

Research RF Safe Research Library Jan 1, 2015

This study examined whether electromagnetic waves from a mobile phone affect brainstem auditory evoked potentials (BAEP) in adult males aged 20–40 years. The right ear was exposed for about 10 minutes and BAEP measures were compared before and after exposure. The abstract reports significant changes in several BAEP…

[Effect of Low-Intensity 900 MHz Frequency Electromagnetic Radiation on Rat Brain Enzyme Activities Linked to Energy Metabolism].

Research RF Safe Research Library Jan 1, 2015

This animal study examined low-intensity 900 MHz electromagnetic radiation (25 μW/cm2) and its effects on rat brain and blood serum enzymes linked to energy metabolism. The authors report that brain creatine kinase activity was the most radiosensitive among the enzymes measured and propose it as a marker of RF…

Effects of extremely low-frequency electric fields at different intensities and exposure durations on mismatch negativity

Research RF Safe Research Library Jul 11, 2014

This rat study examined whether 50-Hz extremely low-frequency electric fields at 12 or 18 kV/m for 2 or 4 weeks affect mismatch negativity (MMN) and markers of oxidative damage/apoptosis in brain tissue. MMN amplitude was reported to be significantly reduced only in the 18 kV/m, 4-week exposure group versus the…

Occupational extremely low-frequency magnetic field exposure and selected cancer outcomes in a prospective Dutch cohort

Research RF Safe Research Library Jan 1, 2014

This prospective Dutch cohort (120,852 participants; 17.3 years follow-up) examined occupational ELF magnetic field exposure and incidence of several cancers. No associations were reported for lung, breast, or brain cancer across multiple exposure metrics. In men, high occupational exposure was associated with…

Assessment of auditory evoked potential in long-term mobile phone users.

Research RF Safe Research Library Jan 1, 2014

This cross-sectional study assessed auditory brainstem responses in 173 long-term mobile phone users aged about 17–39 years. The authors report significant differences in ABR wave and interpeak latencies across age groups, with prolonged average wave I–V latencies in the 20–29 year group. They interpret the latency…

Spatial learning, monoamines and oxidative stress in rats exposed to 900 MHz electromagnetic field in combination with iron overload.

Research RF Safe Research Library Jan 1, 2014

This animal study tested whether 900 MHz EMF exposure, alone or combined with brain iron overload, affects cognition and brain biochemistry in Long-Evans rats. EMF-exposed rats showed impairment in an object exploration task and changes in monoamine content (notably in the hippocampus), while other spatial…

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