A Systematic Review of the Impact of Electromagnetic Waves on Living Beings
Research
RF Safe Research Library
Jan 1, 2025
This PRISMA-adherent systematic review searched PubMed, Scopus, and the Cochrane Library for studies (2017–2024) on physiological or behavioral responses to EMF exposure, emphasizing studies reporting harmful or concerning effects. Across 24 included studies (human non-randomized, in vitro, and animal), the review…
Systematic reviews and meta-analyses for the WHO assessment of health effects of exposure to radiofrequency electromagnetic fields, an introduction
Research
RF Safe Research Library
Jan 1, 2025
This editorial introduces a special issue supporting the WHO assessment of health effects from RF-EMF exposure, based on nine protocols and twelve systematic reviews developed over four years by more than 80 experts. It summarizes that human evidence for major cancers was moderate-certainty for no or only small…
Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats
Research
RF Safe Research Library
Jan 1, 2025
This randomized controlled animal study examined chronic 35.5 GHz millimeter wave exposure in male Wistar rats (2 hours/day for 60 days) compared with control and sham groups. The exposed group showed reduced sperm count and viability along with testicular histopathological changes. Oxidative stress markers shifted…
From particulates to pathways: environmental exposures and their impact on Alzheimer's disease
Research
RF Safe Research Library
Jan 1, 2025
This review discusses how environmental exposures across air, water, and soil pollutants may influence Alzheimer's disease (AD) onset and progression. It highlights EMFs as a potential aggravating factor, reporting associations with oxidative stress, inflammation, calcium dysregulation, and accelerated amyloid-beta…
Impact of in vitro exposure to 5G-modulated 3.5 GHz fields on oxidative stress and DNA repair in skin cells
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study tested whether 5G-modulated 3.5 GHz RF-EMF exposure affects oxidative stress and DNA repair in human skin cells. Under acute exposure conditions (up to 24–48h) at SARs up to 4 W/kg, the authors report no significant changes in ROS markers, no adaptive response to oxidative challenge, and no…
A Prolonged exposure to Wi-Fi Radiation Induces Neurobehavioral Changes and Oxidative Stress in Adult Zebrafish
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RF Safe Research Library
Jan 1, 2025
This animal study exposed adult zebrafish to 2.45 GHz Wi‑Fi radiation for 4 hours daily over 30 consecutive days. The authors report neurobehavioral impairments with altered locomotion, alongside decreased acetylcholinesterase and increased brain oxidative stress. They conclude these findings indicate a safety risk…
Protective effects of quercetin against 3.5 GHz RF radiation-induced thyroid dysfunction and oxidative stress in rats
Research
RF Safe Research Library
Jan 1, 2025
This rat study examined repeated 3.5 GHz RF exposure (2 hours/day, 5 days/week for 30 days) and thyroid-related outcomes, with and without quercetin. The abstract reports altered thyroid hormones (lower T3/T4, higher TSH) and increased oxidative stress in thyroid tissue after RF exposure. Quercetin appeared partially…
The effects of short-term and long-term 2100 MHz radiofrequency radiation on adult rat auditory brainstem response
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined 2100 MHz radiofrequency radiation exposure effects on auditory brainstem responses and brain oxidative/ultrastructural markers in adult rats. The 1-week exposure group showed prolonged ABR latencies and biochemical/structural changes consistent with oxidative stress and cellular injury. The…
Mitigation of 3.5 GHz Electromagnetic Field-Induced BV2 Microglial Cytotoxicity by Polydeoxyribonucleotide
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study exposed BV2 mouse microglial cells to 3.5 GHz EMF for 2 hours and reports reduced cell growth and increased apoptosis alongside oxidative stress and signaling changes. The authors report that ROS generation and activation of JNK-1/2 and p38 MAPK were key events in the observed cytotoxicity.…
A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields
Research
RF Safe Research Library
Jan 1, 2025
This narrative review discusses biological mechanisms and reported health effects of anthropogenic extremely low frequency (ELF) and wireless communication (WC) electromagnetic fields. It highlights oxidative stress and DNA damage as key mechanistic endpoints and proposes an IFO-VGIC pathway linking EMF exposure to…
Exploring the impact of environmental factors on male reproductive health through epigenetics
Research
RF Safe Research Library
Jan 1, 2025
This narrative review discusses how environmental factors may affect male reproductive health through epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation. It reports that electromagnetic radiation, particularly from mobile phones and wireless…
Potential Impacts of Radiofrequency Electromagnetic Fields on the Central Nervous System, Brain Neurotransmitter Dynamics and Reproductive System
Research
RF Safe Research Library
Jan 1, 2025
This review discusses potential impacts of radiofrequency electromagnetic fields from technologies such as Wi‑Fi and mobile phones on the central nervous system, neurotransmitter dynamics, and reproductive health. It describes proposed mechanisms including oxidative stress, thermal effects, altered neurotransmitter…
Melatonin ameliorates RF-EMR-induced reproductive damage by inhibiting ferroptosis through Nrf2 pathway activation
Research
RF Safe Research Library
Jan 1, 2025
This animal study reports that prolonged RF-EMR exposure (2.45 GHz for 8 weeks) increased oxidative stress and ferroptosis in mouse testicular tissue and was associated with reduced sperm quality. Melatonin administration reportedly mitigated oxidative injury and inhibited ferroptosis. The abstract attributes the…
Effects of 700MHz radiofrequency radiation (5G lower band) on the reproductive parameters of female Wistar rats
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined short- and long-term 700 MHz (lower-band 5G) radiofrequency exposure in female Wistar rats, comparing control, sham, and exposed groups. It reports no DNA damage and no change in estrous cycle length, but increased ovarian oxidative stress markers in exposed animals. Long-term exposure was…
The effects of radiofrequency radiation on male reproductive health and potential mechanisms (Review)
Research
RF Safe Research Library
Jan 1, 2025
This narrative review summarizes human and animal research on radiofrequency (RF) radiation exposure (e.g., mobile phones, Wi‑Fi, occupational sources) and male reproductive outcomes. It reports that the literature links RF exposure with reduced sperm quality and increased DNA damage, often alongside oxidative stress…
Assessing cell viability and genotoxicity in Trigonella foenum-graecum L. exposed to 2100 MHz and 2300 MHz electromagnetic field radiations.
Research
RF Safe Research Library
Jan 1, 2025
This experimental study assessed cytotoxic and genotoxic endpoints in Trigonella foenum-graecum L. exposed to 2100 MHz and 2300 MHz EMF-r for 0.5–8 h/day. The authors report reduced root/shoot growth at longer daily exposures, increased chromosomal aberrations compared with controls, and reduced cell viability.…
Acute exposure to 27.12 MHz radiofrequency electromagnetic field disrupts blood-brain barrier integrity via eNOS activation and occludin down-regulation.
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined 27.12 MHz RF-EMF exposure for 30, 180, or 360 minutes in female Wistar rats and assessed markers related to blood-brain barrier integrity. The authors report increased eNOS expression after 30 minutes without oxidative stress or inflammation, alongside decreased occludin expression. Longer…
Effect of ELF-EMF on cognitive functions, analgesia, and oxidative stress in rats with PTZ-induced epilepsy.
Research
RF Safe Research Library
Jan 1, 2025
This animal study tested repeated 50 Hz, 5 mT ELF-EMF exposure in rats with and without PTZ-induced epilepsy. The authors report changes in learning/short-term memory in the EMF+PTZ group versus PTZ alone and increased analgesia latency in EMF-exposed groups. PTZ increased oxidative stress (TOS) in brain regions, and…
Effect of 900 MHz Electromagnetic Field Exposure During Different Trimesters of Pregnancy on TRPM2-Mediated Ferroptosis and Neurotoxicity in the Trigeminal Ganglion of Rats: Protective Role of Ferrostatin-1.
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined prenatal 900 MHz EMF exposure during different pregnancy trimesters and measured oxidative stress, inflammatory, apoptotic, and TRPM2-related markers in rat offspring trigeminal ganglia at postnatal day 28. The abstract reports increased oxidative stress/lipid peroxidation, inflammation,…
Prophylactic Effects of Radiofrequency Electromagnetic Field on Pulmonary Ischemia-Reperfusion via HIF-1α/eNOS Pathway and BCL2/BAX Signaling.
Research
RF Safe Research Library
Jan 1, 2025
This animal study tested whether RF-EMF exposure modifies lung ischemia-reperfusion injury in male Wistar rats. IR increased histologic injury, inflammatory/apoptotic markers, oxidative stress indices, and Hif-1α/eNOS/BAX while decreasing BCL2. The IR + RF-EMF group reportedly improved across measured parameters, and…
Role of radio-frequency electromagnetic waves in causing oxidative stress
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed fertilized chick eggs to a nearby 1800 MHz mobile phone that was called repeatedly (50 minutes/day) and assessed embryos at days 10 and 15. The exposed group reportedly showed mitochondrial abnormalities in liver, brain, and heart tissues on electron microscopy, along with increased HSP70 in…
Investigating the effect of radiofrequency electromagnetic field exposure on molecular pathways related to insulin resistance and adipogenesis in zebrafish embryos - A pilot study without quantitative exposure metrics.
Research
RF Safe Research Library
Jan 1, 2024
This pilot animal study exposed zebrafish embryos to 900 MHz RF-EMF for 30 or 60 minutes per day until 96 hours post-fertilization and assessed gene expression and physiological endpoints. The authors report reduced expression of lepa, ins, and pparg, changes in oxidative stress markers consistent with increased…
The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional…
Transcriptomic Analysis of Gene Expression and Effect of Electromagnetic Field in Brain Tissue after Traumatic Brain Injury.
Research
RF Safe Research Library
Jan 1, 2024
This pilot animal study used a Yucatan miniswine model of traumatic brain injury with and without EMF stimulation to examine differential gene expression in injured versus non-injured cortex tissue. The authors report multiple differentially expressed genes linked to immune infiltration, myelination, oxidative stress…
Comparison of pulsed and continuous electromagnetic field generated by WPT system on human dermal and neural cells.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study tested electromagnetic fields generated by a prototype wireless power transfer (wireless charging) system on four human dermal and neural cell lines. Across pulsed and continuous exposure conditions, the authors report no negative effects on morphology/cytoskeleton, viability/mitosis,…