Regulation of skeletal myogenesis in C2C12 cells through modulation of Pax7, MyoD, and myogenin via different low-frequency electromagnetic field energies.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study examined how low-frequency electromagnetic fields (LF-EMF) at different magnetic flux densities influence skeletal myogenesis in C2C12 cells. The authors report that 2.0 mT LF-EMF activated cells and increased PAX7, while 1.5 mT increased MyoD and myogenin expression. They conclude that different…
Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study.
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RF Safe Research Library
Jan 1, 2022
This in vitro study evaluated short-term extremely low frequency electromagnetic field (ELF-EMF) exposure and silver nanoparticles (AgNPs), alone and combined, for antibacterial effects and apoptosis induction in MCF-7 breast cancer cells. The authors report time-dependent reductions in bacterial viable counts, with…
Cancer on-target: Selective enhancement of 3-bromopyruvate action by an electromagnetic field in vitro.
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RF Safe Research Library
Jan 1, 2022
This in vitro study tested continuous or pulsed ELF electromagnetic field exposure in human cancer cells treated with the anticancer agent 3-bromopyruvate (3BP). The authors report that ELF-EMF enhanced 3BP anti-cancer activity, which they link to reduced TNFα secretion, p21/p27-associated G2/M arrest, and cancer…
The effect of 900 MHz electromagnetic fields on biological pathways induced by electrochemotherapy.
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RF Safe Research Library
Jan 1, 2021
This study examined whether 900 MHz RF-EMF exposure modifies biological pathways associated with electrochemotherapy (ECT) in 4T1 cells and in mice bearing 4T1 tumors. At the highest reported power density (349 µW/cm), RF exposure was reported to increase ECT-induced tumor hypoxia and increase IFN-γ compared with ECT…
The Short-Term Effect of Occupational Levels of 50 Hz Electromagnetic Field on Human Heart Rate Variability.
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RF Safe Research Library
Jan 1, 2021
This double-blind randomized sham-controlled repeated-measures study examined short-term 50 Hz ELF-EMF exposure (28 μT) to the chest and its effects on HR and HRV in 34 healthy young men. HR deceleration occurred in both EMF and sham conditions, but several HRV indices (SDNN, RMSSD, LF, HF) increased only in the EMF…
Conformational changes of β-thalassemia major hemoglobin and oxidative status of plasma after in vitro exposure to extremely low-frequency electromagnetic fields: An artificial neural network analysis.
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RF Safe Research Library
Jan 1, 2021
This in vitro study exposed blood samples from β-thalassemia major patients and matched healthy donors (n=12 each) to 50 Hz ELF-EMF at 0.5 and 1 mT for 1–2 hours. The authors report that two-hour exposure induced significant oxidative changes in β-thalassemia major samples and examined protein/Hb structural features…
Pulsed and Discontinuous Electromagnetic Field Exposure Decreases Temozolomide Resistance in Glioblastoma by Modulating the Expression of O-Methylguanine-DNA Methyltransferase, Cyclin-D1, and p53.
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RF Safe Research Library
Jan 1, 2021
This in vitro study evaluated 50 Hz, 70 G electromagnetic field exposure in combination with temozolomide (TMZ) in T98 and A172 glioblastoma cell lines. The authors report that EMF plus TMZ increased cell death and reduced migration potential compared with controls. They also report increased p53 gene expression and…
Comparing the Effects of Long-term Exposure to Extremely Low-frequency Electromagnetic Fields With Different Values on Learning, Memory, Anxiety, and β-amyloid Deposition in Adult Rats.
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RF Safe Research Library
Jan 1, 2021
This animal study exposed adult male rats to 50 Hz ELF-EMF at 1, 100, 500, or 2000 μT for 1 hour/day over two months and assessed behavior and brain markers. The authors report increased memory retention (higher step-through latency) alongside increased anxiety-like behavior (reduced open-arm entries), particularly…
Translocation of silica nanospheres through giant unilamellar vesicles (GUVs) induced by a high frequency electromagnetic field.
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RF Safe Research Library
Jan 1, 2021
This in vitro study used giant unilamellar vesicles (GUVs) to examine effects of an 18 GHz electromagnetic field on membrane behavior. The authors report increased membrane permeability after exposure, inferred from internalisation of 23.5 nm hydrophilic silica nanospheres. Complementary molecular dynamics…
Improved Calculation Method of Coupling Factors for Low-Frequency Wireless Power Transfer Systems.
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RF Safe Research Library
Jan 1, 2021
This engineering/methods study addresses computational artifacts that can affect coupling factor calculations for localized EMF exposure assessment in IEC 62311/62233, particularly below 10 MHz. The authors propose using the 99.99th percentile rather than the maximum internal quantity to mitigate abnormal peaks from…
Electromagnetic Field Stimulation Attenuates Phasic Nociception after Complete Spinal Cord Injury in Rats.
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Jan 1, 2021
This animal study evaluated whole-body extremely low-frequency EMF stimulation after thoracic complete spinal cord injury in adult male rats. The authors report reduced nociceptive behaviors (hyperalgesia/allodynia) from week 6 onward and restoration of spinal reflexes by week 8. They also report lower glutamate at…
EVALUATION OF BCL2 AND ITS REGULATORY MIRS, MIR-15-B AND MIR-16 EXPRESSION CHANGES UNDER THE EXPOSURE OF EXTREMELY LOW-FREQUENCY ELECTROMAGNETIC FIELDS ON HUMAN GASTRIC CANCER CELL LINE.
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RF Safe Research Library
Jan 1, 2021
This in vitro study examined whether extremely low-frequency electromagnetic fields (ELF-EMF) at 0.2 or 2 mT (continuous or 1.5 h on/1.5 h off) for 18 hours alter viability and gene/miRNA expression in AGS gastric cancer cells. The authors report a significant reduction in cell viability at 2 mT continuous exposure.…
Effects of excessive use of mobile phone technology in India on human health during COVID-19 lockdown.
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RF Safe Research Library
Jan 1, 2021
This cross-sectional online survey study (n=122) examined increased dependency on mobile phone technology and electronic gadgets in India during the COVID-19 lockdown. Most participants reported increased usage and perceived increased risk of health problems from excessive use. The authors conclude that technology…
Morphometric analysis - effect of the radiofrequency interface of electromagnetic field on the size of hatched Dermacentor reticulatus larvae.
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Jan 1, 2021
This animal study examined whether exposing Dermacentor reticulatus tick eggs to 900 MHz RF-EMF for 30, 60, or 90 minutes affects the size of hatched larvae. The authors report that the 60-minute exposure group produced larvae with larger measurements across four body traits compared with unexposed controls and other…
Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on male fertility and pregnancy and birth outcomes: Protocols for a systematic review of experimental studies in non-human mammals and in human sperm exposed in vitro.
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RF Safe Research Library
Jan 1, 2021
This paper presents protocols for a systematic review of experimental studies assessing RF-EMF exposure (100 kHz–300 GHz) and outcomes related to male fertility and pregnancy/birth effects. The review will cover three evidence streams: non-human mammal male reproductive outcomes, human sperm exposed in vitro, and in…
The Time-Dependence of Three Different Modes of ELF-EMF Stimulation on LTP at Schaffer Collateral-CA1 Synapses.
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Jan 1, 2021
This animal ex vivo study tested whether short-term 15 Hz/2 mT ELF-EMF exposure alters LTP at rat hippocampal SC-CA1 synapses. Across sinusoidal, pulsed, and rhythm-pulsed modes, the authors report reduced LTP versus control, with greater inhibition at longer exposure durations (10–60 s). Sinusoidal stimulation…
Effects induced by a 50 Hz electromagnetic field and doxorubicin on Walker-256 carcinosarcoma growth and hepatic redox state in rats.
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RF Safe Research Library
Jan 1, 2021
This animal study compared 50 Hz extremely low-frequency EMF exposure with doxorubicin (and their combination) in Walker-256 carcinosarcoma-bearing rats, assessing tumor growth and liver redox-related outcomes. DOX and DOX+EMF were reported to inhibit tumor growth more than EMF alone, though EMF alone also showed an…
The guardians of germ cells; Sertoli-derived exosomes against electromagnetic field-induced oxidative stress in mouse spermatogonial stem cells.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed mouse spermatogonial stem cells to 50 Hz EMF (2.5 mT; 1 h/day for 5 days) and assessed oxidative stress and cell health outcomes. The authors report increased ROS and apoptosis with reduced antioxidant (catalase) expression, viability, and colonization after EMF exposure. Sertoli…
Modulation of Crystallinity through Radiofrequency Electromagnetic Fields in PLLA/Magnetic Nanoparticles Composites: A Proof of Concept.
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RF Safe Research Library
Jan 1, 2021
This materials proof-of-concept study explored using radiofrequency EMF to heat magnetic nanoparticles dispersed in PLLA to modulate polymer properties. Heating was monitored by infrared camera, and polymer changes were assessed by differential scanning calorimetry and nanoindentation. The authors report that EMF…
Impact of low-level electromagnetic fields on the inducibility of atrial fibrillation in the electrophysiology laboratory.
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RF Safe Research Library
Jan 1, 2021
This randomized sham-controlled study tested low-level electromagnetic field stimulation (3.2 × 10 G at 0.89 Hz) applied around the head in patients undergoing ablation for paroxysmal atrial fibrillation. Eighteen patients completed the protocol, and LL-EMF was associated with shorter pacing-induced AF episodes after…
Exposure to long-term evolution radiofrequency electromagnetic fields decreases neuroblastoma cell proliferation via Akt/mTOR-mediated cellular senescence.
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Jan 1, 2021
This in vitro study examined LTE RF-EMF exposure effects on SH-SY5Y neuroblastoma cells. The authors report reduced cell proliferation and a G0/G1 cell-cycle delay after 1760 MHz exposure at 4 W/kg for 4 hr/day over 4 days. They report no marked DNA damage signal (γH2AX) and no apoptosis activation, but increased…
Radiofrequency EMF irradiation effects on pre-B lymphocytes undergoing somatic recombination.
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RF Safe Research Library
Jan 1, 2021
This in vitro study exposed developing pre-B lymphocytes undergoing V(D)J recombination to low-intensity RF EMFs for 48 hours across 720–1224 MHz. The authors report a frequency- and dose-dependent decrease in recombination, with stronger reductions around 950–1000 MHz at relatively low power densities. γH2AX levels…
Up-regulation of miR-144 and miR-375 in the human gastric cancer cell line following the exposure to extremely low-frequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed AGS human gastric cancer cells to 50 Hz ELF magnetic fields at 0.2 or 2 mT for 18 hours (continuous or intermittent). The authors report reduced cell viability versus control and up-regulation of miR-144 and miR-375 during exposure. They also report miR levels decreased 18 and 36 hours…
Exposure to RF-EMF Alters Postsynaptic Structure and Hinders Neurite Outgrowth in Developing Hippocampal Neurons of Early Postnatal Mice.
Research
RF Safe Research Library
Jan 1, 2021
This animal and primary neuron culture study exposed early postnatal mice to whole-body RF-EMF (SAR 4.0 W/kg) for 5 hours/day from P1 to P28. The authors report reductions in dendritic spine measures (notably mushroom-type spines), decreased glutamate receptor expression in mushroom-type spines, and lower BDNF…
Nonionizing Electromagnetic Field: A Promising Alternative for Growing Control Yeast.
Research
RF Safe Research Library
Jan 1, 2021
This laboratory study examined radiofrequency EMF exposure between 1 and 5.9 GHz as a method to control yeast growth relevant to food spoilage. The authors report reduced yeast viability at all tested frequencies and note that antenna-to-sample distance affected the outcome. Electron microscopy findings are described…