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Filters: category: Mechanisms & Biomarkers Clear

Effect of dual RF-EMF and pulsed magnetic field exposure on eNOS expression and histological integrity in male rat reproductive tissues.

Research RF Safe Research Library Jan 1, 2026

This rat study examined combined RF-EMF and pulsed magnetic field exposure across multiple dosing schedules up to one month, assessing reproductive and related tissues with RT-qPCR, histopathology, and immunohistochemistry. The authors report increased eNOS expression with minimal VEGF change and generally preserved…

Transcriptomic Analysis of Gene Expression and Effect of Electromagnetic Field in Brain Tissue after Traumatic Brain Injury.

Research RF Safe Research Library Jan 1, 2024

This pilot animal study used a Yucatan miniswine model of traumatic brain injury with and without EMF stimulation to examine differential gene expression in injured versus non-injured cortex tissue. The authors report multiple differentially expressed genes linked to immune infiltration, myelination, oxidative stress…

Exposure to a 900 MHz electromagnetic field induces a response of the honey bee organism on the level of enzyme activity and the expression of stress-related genes.

Research RF Safe Research Library Jan 1, 2023

This animal study exposed one-day-old worker honey bees to 900 MHz RF-EMF at 12, 28, or 61 V/m for 15 minutes, 1 hour, or 3 hours, with an unexposed control group. The authors report changes in hemolymph enzyme activity and in expression of several stress-related genes following exposure. They state the pattern…

The effect of the electromagnetic field on the physicochemical properties of isolated corn starch obtained of plants from irradiate seeds.

Research RF Safe Research Library Jan 1, 2023

This study examined whether exposing maize seeds to electromagnetic fields (23, 70, 118 μT) for 15 days alters physicochemical properties of starch isolated from the resulting grains. SEM and X-ray diffraction results suggest starch morphology and orthorhombic crystalline structure were largely unchanged, though…

First Identification of the Effects of Low Frequency Electromagnetic Field on the Micromolecular Changes in Adipose Tissue-Derived Mesenchymal Stem Cells by Fourier Transform Infrared Spectroscopy.

Research RF Safe Research Library Jan 1, 2021

This in vitro study exposed adipose tissue-derived mesenchymal stem cells to a continuous 50 Hz electromagnetic field at 1.5 mT for 24, 48, or 72 hours and assessed micromolecular changes using FTIR spectroscopy. The authors report the largest FTIR spectral differences versus control in nucleic acids and proteins…

Electromagnetic Field (EMF) Radiation Alters Estrogen Release from the Pig Myometrium during the Peri-Implantation Period.

Research RF Safe Research Library Jan 1, 2021

This ex vivo animal-tissue study tested whether ELF-EMF exposure (50 or 120 Hz for 2 or 4 hours) alters estrogenic activity in pig myometrium during the peri-implantation period. The authors report EMF-associated changes in estrogen-related gene transcripts and aromatase abundance, with progesterone diminishing some…

Treating honey bees with an extremely low frequency electromagnetic field and pesticides: Impact on the rate of disappearance of azoxystrobin and λ-cyhalothrin and the structure of some functional groups of the probabilistic molecules.

Research RF Safe Research Library Jan 1, 2020

This laboratory study examined whether 50 Hz (ELF) electromagnetic field exposure changes pesticide disappearance rates and molecular functional group signatures in honey bees. EMF altered the disappearance rates of azoxystrobin and λ-cyhalothrin within 6 hours, with different patterns depending on whether pesticides…

Geobacter sulfurreducens-inoculated bioelectrochemical system reveals the potential of metabolic current in defining the effect of extremely low-frequency electromagnetic field on living cells.

Research RF Safe Research Library Jan 1, 2019

This laboratory study exposed a Geobacter sulfurreducens-inoculated bioelectrochemical system to 0–128 Gauss extremely low-frequency electromagnetic fields. The authors report increased and oscillatory metabolic current under ELF-EMF exposure, with dose-dependent effects and a linear relationship between oscillation…

Effects of single and combined low frequency electromagnetic fields and simulated microgravity on gene expression of human mesenchymal stem cells during chondrogenesis.

Research RF Safe Research Library Jan 1, 2018

This in vitro study exposed human mesenchymal stem cell pellets undergoing chondrogenesis to simulated microgravity (SMG), low-frequency EMF (5 mT, 15 Hz), or both for 3 weeks. SMG significantly changed gene expression and reduced chondrogenic marker expression (including COL2A1). LF-EMF alone showed no…

Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields.

Research RF Safe Research Library Jan 1, 2017

This in vitro study used proteome-wide semi-quantitative mass spectrometry to assess molecular changes after short-term exposure to ELF (50 Hz), UMTS (2.1 GHz), and WiFi (5.8 GHz) in human and mouse cell types. The authors report that fewer than 1% of quantified proteins changed slightly in abundance and that…

Subzero 12-hour Nonfreezing Cryopreservation of Porcine Heart in a Variable Magnetic Field.

Research RF Safe Research Library Jan 1, 2015

This animal organ-preservation study compared 12-hour porcine heart preservation at -3°C using a device generating a variable magnetic field versus conventional 4°C preservation. The subzero variable-magnetic-field condition showed higher myocardial ATP, lower lactate, and less mitochondrial ultrastructural damage…

[Effect of Low-Intensity 900 MHz Frequency Electromagnetic Radiation on Rat Brain Enzyme Activities Linked to Energy Metabolism].

Research RF Safe Research Library Jan 1, 2015

This animal study examined low-intensity 900 MHz electromagnetic radiation (25 μW/cm2) and its effects on rat brain and blood serum enzymes linked to energy metabolism. The authors report that brain creatine kinase activity was the most radiosensitive among the enzymes measured and propose it as a marker of RF…

Effect of ELF-EMF Exposure on Human Neuroblastoma Cell Line: a Proteomics Analysis

Research RF Safe Research Library Jan 1, 2014

This in vitro study exposed SH-SY5Y human neuroblastoma cells to a 2 mT, 50 Hz magnetic field for 3 hours and assessed protein expression using proteomics. The authors report that 189 proteins changed expression in exposed cells compared with controls, with PCA/clustering separating samples by condition. They…

[The effect of weak low-frequency magnetic fields on the intracellular calcium-dependent proteinases of fish].

Research RF Safe Research Library Jan 1, 2013

This animal study examined in vivo and in vitro effects of weak, low-frequency magnetic fields described as having resonance parameters for calcium ions. The authors report a considerable decrease in activity of calcium-dependent proteinases (calpains) in fish skeletal muscle and brain following exposure. The…

[Modulation of Ca(2+)-dependent proteinase activity in invertebrates and fish under the action of weak low-frequency magnetic fields].

Research RF Safe Research Library Jan 1, 2013

This study examined whether weak low-frequency magnetic fields affect Ca2+-dependent proteinases (calpains) in fish and invertebrates using in vivo and in vitro experiments. The authors report a significant decrease in calpain activity in animals exposed to a field tuned to Ca2+ parametric resonance, and substantial…

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