Frequency-tuned electromagnetic field therapy improves post-stroke motor function: A pilot randomized controlled trial.
Research
RF Safe Research Library
Jan 1, 2022
This pilot randomized, sham-controlled, double-blind trial evaluated extremely low frequency, low-intensity ENTF electromagnetic field therapy in subacute ischemic stroke patients with impaired upper extremity function. The per-protocol results reported greater improvements in motor function and disability outcomes…
Cone Beam Computed Tomography in the Assessment of the Effectiveness of Physical Therapy with the Use of the Electromagnetic Field Combined with Light Radiation Emitted by LEDs in the Treatment of Inflammation of the Paranasal Sinuses-A Case Study.
Research
RF Safe Research Library
Jan 1, 2022
This case study used cone beam computed tomography (CBCT) to assess a physical therapy approach combining extremely low frequency electromagnetic field (ELF-EMF) exposure with LED light for paranasal sinusitis. In one 39-year-old female patient, CBCT findings reportedly showed near-complete restoration of sinus…
Effects of prolonged exposure to ELF-EMF on HERVs expression in human melanoma cells.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study examined whether 96-hour exposure to 50 Hz ELF-EMF affects expression of human endogenous retroviruses (HERV-H, HERV-K, HERV-W) in SK-MEL-37 human melanoma cells. Cells were continuously exposed at 1.5 or 3 mT and HERV env mRNA levels were measured by qPCR. The authors report significant…
Influence of Schumann Range Electromagnetic Fields on Components of Plant Redox Metabolism in Wheat and Peas.
Research
RF Safe Research Library
Jan 1, 2022
This study examined whether Schumann Resonance-range ELF electromagnetic fields (7.8, 14.3, 20.8 Hz) influence redox metabolism components in wheat and pea leaves after short (30 min) and long (18 days) exposures. The authors report that short-time exposure produced more pronounced biological effects than long-time…
Protein expression changes during phagocytosis influenced by low-frequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study examined whether a low-frequency EMF (30 mT, 7 Hz for 3 h) alters phagocytosis of latex beads and immune-related protein/gene expression in the human Mono Mac 6 macrophage cell line. The authors report that EMF exposure influenced phagocytosis-associated molecular markers, with notable changes in…
Physiotherapeutic Reduction of Orofacial Pain Using Extremely Low-Frequency Electromagnetic Field and Light-Emitting Diode Therapy-A Pilot Study.
Research
RF Safe Research Library
Jan 1, 2022
This randomized pilot study evaluated whether adding combined extremely low-frequency electromagnetic field (ELF EMF) and LED physiotherapy to standard analgesics reduces postoperative orofacial pain after orthognathic surgery. The physiotherapy group reportedly experienced faster pain reduction than controls. The…
Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study evaluated short-term extremely low frequency electromagnetic field (ELF-EMF) exposure and silver nanoparticles (AgNPs), alone and combined, for antibacterial effects and apoptosis induction in MCF-7 breast cancer cells. The authors report time-dependent reductions in bacterial viable counts, with…
The Short-Term Effect of Occupational Levels of 50 Hz Electromagnetic Field on Human Heart Rate Variability.
Research
RF Safe Research Library
Jan 1, 2021
This double-blind randomized sham-controlled repeated-measures study examined short-term 50 Hz ELF-EMF exposure (28 μT) to the chest and its effects on HR and HRV in 34 healthy young men. HR deceleration occurred in both EMF and sham conditions, but several HRV indices (SDNN, RMSSD, LF, HF) increased only in the EMF…
Conformational changes of β-thalassemia major hemoglobin and oxidative status of plasma after in vitro exposure to extremely low-frequency electromagnetic fields: An artificial neural network analysis.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed blood samples from β-thalassemia major patients and matched healthy donors (n=12 each) to 50 Hz ELF-EMF at 0.5 and 1 mT for 1–2 hours. The authors report that two-hour exposure induced significant oxidative changes in β-thalassemia major samples and examined protein/Hb structural features…
Pulsed and Discontinuous Electromagnetic Field Exposure Decreases Temozolomide Resistance in Glioblastoma by Modulating the Expression of O-Methylguanine-DNA Methyltransferase, Cyclin-D1, and p53.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study evaluated 50 Hz, 70 G electromagnetic field exposure in combination with temozolomide (TMZ) in T98 and A172 glioblastoma cell lines. The authors report that EMF plus TMZ increased cell death and reduced migration potential compared with controls. They also report increased p53 gene expression and…
Comparing the Effects of Long-term Exposure to Extremely Low-frequency Electromagnetic Fields With Different Values on Learning, Memory, Anxiety, and β-amyloid Deposition in Adult Rats.
Research
RF Safe Research Library
Jan 1, 2021
This animal study exposed adult male rats to 50 Hz ELF-EMF at 1, 100, 500, or 2000 μT for 1 hour/day over two months and assessed behavior and brain markers. The authors report increased memory retention (higher step-through latency) alongside increased anxiety-like behavior (reduced open-arm entries), particularly…
The Dynamic(s) of Adipose Stem Cell System, Their Survival, and Cessation under the Influence of Electromagnetic Fields.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study examined how extremely low frequency EMF affects adipose-derived stem cell proliferation, cell cycle, viability, and death using fluorescent microscopy and flow cytometry. Under continuous exposure at 76.6 Hz and 20 T (ICR-based parameters), the authors report a statistically significant increase…
Impact of low-level electromagnetic fields on the inducibility of atrial fibrillation in the electrophysiology laboratory.
Research
RF Safe Research Library
Jan 1, 2021
This randomized sham-controlled study tested low-level electromagnetic field stimulation (3.2 × 10 G at 0.89 Hz) applied around the head in patients undergoing ablation for paroxysmal atrial fibrillation. Eighteen patients completed the protocol, and LL-EMF was associated with shorter pacing-induced AF episodes after…
Synergic effects of extremely low-frequency electromagnetic field and betaine on in vitro osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study tested 50 Hz, 1 mT ELF-EMF exposure (8 h/day for 21 days) and betaine (10 mM) during osteogenic induction of human adipose-derived mesenchymal stem cells. The authors report ELF-EMF decreased osteogenic differentiation and reduced RUNX2 and OCN gene expression compared with non-EMF conditions.…
Effect of extremely low frequency electromagnetic field parameters on the proliferation of human breast cancer.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study tested how varying ELF-EMF parameters (frequency, flux density, duration, and continuous vs switching exposure) affect breast cancer and normal breast epithelial cell lines. The authors report that an optimized switching exposure pattern (7.83 ± 0.3 Hz, 1 mT) reduced viability of MDA-MB-231 cells…
Low-frequency electromagnetic field influences human oral mucosa keratinocyte viability in response to lipopolysaccharide or minocycline treatment in cell culture conditions.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study examined whether low-frequency electromagnetic field (LF-EMF) exposure affects viability of human oral mucosa keratinocytes. Apoptosis (early/late) and necrosis were measured by flow cytometry, including conditions with lipopolysaccharide (LPS) or minocycline. The authors report that LF-EMF, alone…
Extremely low frequency electromagnetic fields promote cognitive function and hippocampal neurogenesis of rats with cerebral ischemia.
Research
RF Safe Research Library
Jan 1, 2021
This animal study evaluated whether ELF-EMF exposure affects recovery-related outcomes after cerebral ischemia in rats. Rats exposed to 50 Hz, 1 mT ELF-EMF for 2 hours daily over 28 days showed better Morris water maze performance than untreated rats. The study also reports increased hippocampal neurogenesis markers…
Synergistic effect of electromagnetic fields and nanomagnetic particles on osteogenesis through calcium channels and p-ERK signaling.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro and animal study evaluated whether extremely low frequency EMF exposure (1 mT, 45 Hz, 8 h/day) combined with Fe-based nanomagnetic particles enhances osteogenesis. The authors report no detectable cytotoxicity and increased osteogenic markers/proteins with combined NMP + EMF exposure, alongside…
Enhancement in the ATP level and antioxidant capacity of under continuous exposure to extremely low-frequency electromagnetic field for multiple generations.
Research
RF Safe Research Library
Jan 1, 2020
This multi-generation animal study exposed worms continuously to 50 Hz, 3 mT extremely low-frequency electromagnetic fields and assessed outcomes in the 15th generation. The study reports increased body length, higher ATP content and ATP synthase activity, and upregulated ATP-related gene expression in exposed worms.…
Effect of Extremely Low Power Time-Varying Electromagnetic Field on Germination and Other Characteristics in Foxtail Millet (Setaria italica) Seeds.
Research
RF Safe Research Library
Jan 1, 2020
This study evaluated extremely low, time-varying EMF “magneto-priming” to optimize germination in foxtail millet seeds using a central composite design and response surface methodology. The authors report optimal germination at 10 Hz, 30,007 nT, and 30 minutes, with improvements in germination percentage and multiple…
Electromagnetic field affects the voltage-dependent potassium channel Kv1.3.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study tested whether extremely low-frequency electromagnetic fields (ELF-EMF) modulate the voltage-gated potassium channel Kv1.3 in Kv1.3-expressing CHO-K1 cells. Cells were exposed to a 20 Hz field at 268 µT or 902 µT while Kv1.3 currents were measured by whole-cell patch clamp. The authors report a…
Treating honey bees with an extremely low frequency electromagnetic field and pesticides: Impact on the rate of disappearance of azoxystrobin and λ-cyhalothrin and the structure of some functional groups of the probabilistic molecules.
Research
RF Safe Research Library
Jan 1, 2020
This laboratory study examined whether 50 Hz (ELF) electromagnetic field exposure changes pesticide disappearance rates and molecular functional group signatures in honey bees. EMF altered the disappearance rates of azoxystrobin and λ-cyhalothrin within 6 hours, with different patterns depending on whether pesticides…
Low-frequency electromagnetic fields promote hair follicles regeneration by injection a mixture of epidermal stem cells and dermal papilla cells.
Research
RF Safe Research Library
Jan 1, 2020
This animal study evaluated whether low-frequency EMF exposure affects bioengineered hair follicle generation in nude mice injected with a mixture of epidermal stem cells and dermal papilla cells. Histology (H&E) at 7 or 14 days suggested more hair follicle eruption and higher density of hair follicle-like structures…
Effect of Rehabilitation with Extremely Low Frequency Electromagnetic Field on Molecular Mechanism of Apoptosis in Post-Stroke Patients.
Research
RF Safe Research Library
Jan 1, 2020
This study evaluated whether adding extremely low frequency electromagnetic field (ELF-EMF) exposure to a rehabilitation program affects apoptosis-related gene expression in post-stroke patients. Forty-eight patients (3–4 weeks post-incident) were divided into ELF-EMF and non-ELF-EMF groups, with the ELF-EMF group…
The effect of electromagnetic fields on survival and proliferation rate of dental pulp stem cells.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study tested whether 50 Hz extremely low-frequency electromagnetic fields (0.5 or 1 mT) affect human dental pulp stem cell survival and proliferation. Using MTT and DAPI assays after 7 days of exposure (20 or 40 min/day), all exposed groups reportedly showed higher viability/proliferation than controls.…