Microglial Response to Inflammatory Stimuli Under Electromagnetic Field Exposure.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study examined whether extremely low frequency EMF exposure alters responses of TNF-α-stimulated human microglial cells (HMC3). Cells exposed to 2.5 or 5 Hz EMF for 3 minutes showed increased survival under high TNF-α conditions and reduced migration compared with TNF-α treatment alone. EMF also…
Activation of matrix metalloproteinases and FoxO3a in HaCaT keratinocytes by radiofrequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed HaCaT human keratinocytes to 1760 MHz RF-EMF (SAR 4.0 W/kg; 2 h/day for 4 days). The authors report increased intracellular ROS and increased expression/activity of several matrix metalloproteinases, along with increased phosphorylation of FoxO3a and ERK1/2. Cell growth/viability and…
Fas/FasL pathway and cytokines in keratinocytes in atopic dermatitis - Manipulation by the electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed keratinocytes from atopic dermatitis patients and healthy controls, plus two keratinocyte cell lines, to a 900 MHz electromagnetic field for 60 minutes. AD-derived keratinocytes showed higher Fas/FasL signaling markers and increased secretion of multiple cytokines versus controls. EMF…
Selenium supplementation ameliorates electromagnetic field-induced oxidative stress in the HEK293 cells.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study examined whether selenium supplementation modifies oxidative stress and apoptosis markers in HEK293 cells exposed to 2.4 GHz EMF. The authors report that EMF exposure increased lipid peroxidation (MDA) and apoptosis-related markers while decreasing antioxidant enzyme activities and bcl-2 versus…