Autophagy mediates the degradation of synaptic vesicles: A potential mechanism of synaptic plasticity injury induced by microwave exposure in rats.
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Jan 1, 2018
This animal study used an in vivo microwave exposure model (30 mW/cm) and reports reversible neuronal injuries in rats. The authors observed cognitive impairment and synaptic plasticity injury in hippocampal neurons following exposure. Autophagy was activated, and autophagosomes showed increased association with…
Effect of 2.45 GHz microwave radiation on the fertility pattern in male mice.
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Jan 1, 2018
This animal study examined 2.45 GHz microwave exposure in male Swiss albino mice for 2 hours per day over 30 days. The authors report increased oxidative stress markers and reduced antioxidant enzymes and testosterone in exposed mice versus sham controls. They also report micronuclei formation in blood and…
2.45 GHz microwave radiation induced oxidative and nitrosative stress mediated testicular apoptosis: Involvement of a p53 dependent bax-caspase-3 mediated pathway.
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Jan 1, 2018
This animal study exposed 12-week-old male mice to 2.45 GHz continuous-wave microwave radiation (average power density 0.0248 mW/cm; whole-body SAR 0.0146 W/kg) for 2 hours/day over 15, 30, or 60 days. The authors evaluated testicular histology, testosterone, oxidative/nitrosative stress markers, antioxidant enzymes,…
Age-dependent effect of long-term microwave radiation on postnatal neurogenesis in rats: morphological and behavioral study.
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Jan 1, 2018
This animal study examined pulsed-wave 2.45 GHz microwave radiation exposure (1 or 3 hours daily for 3 weeks) in adult and juvenile rats and assessed neurogenesis-related markers in the rostral migratory stream. The authors report reduced cell proliferation in adults and longer-lasting effects on cell death after…
From the Cover: 2.45-GHz Microwave Radiation Impairs Hippocampal Learning and Spatial Memory: Involvement of Local Stress Mechanism-Induced Suppression of iGluR/ERK/CREB Signaling.
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Jan 1, 2018
This mouse study examined low-level 2.45 GHz continuous-wave microwave exposure for 2 hours/day over 15, 30, or 60 days. The authors report impaired learning and spatial memory performance on an 8-arm radial maze after exposure. They also report increased corticosterone and stress/inflammatory-related markers with…
Oxidative and mutagenic effects of low intensity GSM 1800 MHz microwave radiation
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Jan 1, 2018
This animal study used developing quail embryos to assess oxidative and mutagenic effects of low-intensity GSM 1800 MHz radiation from a commercial smartphone. The authors report statistically significant increases in oxidative stress markers, DNA integrity damage, and oxidative DNA damage (8-oxo-dG) in exposed…
NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595
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Jan 1, 2018
This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…
Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats
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Mar 1, 2017
This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following…
Effect of long-term exposure of mice to 900 MHz GSM radiation on experimental cutaneous candidiasis.
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Jan 1, 2017
This animal study examined whether long-term 900 MHz GSM-like microwave exposure affects experimentally induced cutaneous candidiasis in BALB/c mice. Exposed mice reportedly had delayed wound healing and higher Candida loads in skin lesions compared with unexposed mice. Following systemic Candida challenge, exposed…
Effects of electromagnetic fields on bone loss in hyperthyroidism rat model.
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Jan 1, 2017
This animal study evaluated whether extremely low frequency EMF exposure affects bone loss in a levothyroxine-induced hyperthyroidism rat model. Rats exposed to 15 Hz/1 mT EMF plus levothyroxine showed improved bone mineral density, mechanical measures, and partially restored trabecular bone architecture compared…
No adverse effects detected for simultaneous whole-body exposure to multiple-frequency radiofrequency electromagnetic fields for rats in the intrauterine and pre- and post-weaning periods.
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Jan 1, 2017
This animal study exposed pregnant Sprague-Dawley rats and their offspring to simultaneous whole-body multifrequency RF signals spanning 800 MHz to 5.2 GHz. Exposure occurred 20 hours per day from gestational day 7 to weaning, with F1 offspring exposed up to 6 weeks of age. Across multiple endpoints including growth,…
Lasting hepatotoxic effects of prenatal mobile phone exposure.
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Jan 1, 2017
This animal study examined liver outcomes in rat offspring 60 days after prenatal exposure to a 900 MHz electromagnetic field for 24 hours/day during gestation. The exposed group showed biochemical changes consistent with oxidative stress (higher MDA, lower GSH) and elevated liver enzymes (ALT, AST). Histopathology…
Effect of extremely low frequency electromagnetic field on brain histopathology of Caspian Sea Cyprinus carpio.
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Jan 1, 2017
This animal study evaluated 50 Hz extremely low frequency electromagnetic field exposure and brain histopathology in Cyprinus carpio. Fish were sham-exposed or exposed to magnetic field intensities from 0.1 to 7 mT for 0.5 or 1 hour. The authors report severe brain histopathological changes at intensities ≥3 mT,…
Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields.
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Jan 1, 2017
This rat study examined 900 MHz EMF exposure for 60 minutes per day over 15 days and assessed hippocampal and cerebellar outcomes, behavior, and serum enzyme activity. The EMF-only group showed significant neuronal cell losses in multiple brain regions and worse passive avoidance performance compared with other…
Does omega-3 have a protective effect on the rat adrenal gland exposed to 900 MHz electromagnetic fields?
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Jan 1, 2017
This animal study examined whether omega-3 modifies adrenal gland changes in rats exposed to 900 MHz electromagnetic fields. Rats exposed 60 minutes/day for 15 days showed significantly increased adrenal gland volume versus controls. Omega-3 co-treatment was associated with significantly lower adrenal gland volume…
Iron deposition in rabbit cerebellum after exposure to generated and mobile GSM electromagnetic fields.
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Jan 1, 2017
This animal study examined iron distribution in rabbit cerebellum after exposure to RF electromagnetic fields, using light and scanning electron microscopy with energy-dispersive microanalysis. The authors report dystrophic changes in Purkinje cells in irradiated groups and deposits containing multiple elements…
Effects of extremely low frequency electromagnetic fields on morphine analgesia and tolerance in rats.
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Jan 1, 2017
This animal study examined whether extremely low frequency electromagnetic field exposure alters morphine analgesia and tolerance in rats. Rats exposed to a 50 Hz magnetic field (reported as 5 mT) showed higher morphine analgesic effects than rats given morphine without field exposure. In morphine-tolerant rats,…
Electromagnetic fields at a mobile phone frequency (900 MHz) trigger the onset of general stress response along with DNA modifications in Eisenia fetida earthworms.
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Jan 1, 2017
This animal study exposed Eisenia fetida earthworms to 900 MHz electromagnetic fields at 10–120 V/m for 2 hours (with additional tests of longer exposure, modulation, and recovery). The authors report significant DNA modifications across exposure treatments and a decrease in probe hybridisation sites persisting after…
Theta-gamma coupling in hippocampus during working memory deficits induced by low frequency electromagnetic field exposure.
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Jan 1, 2017
This mouse study examined whether 50 Hz, 1 mT electromagnetic field exposure affects working memory and hippocampal electrophysiology. The authors report reduced Y-maze working memory performance after 3 days of EMF exposure, accompanied by decreased hippocampal firing rates. They also report reduced theta and…
Effect of electromagnetic fields and antioxidants on the trace element content of rat teeth.
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Jan 1, 2017
This animal study examined whether extremely low-frequency electromagnetic fields (ELF-EMFs) from a high-voltage source alter trace element concentrations in rat teeth and whether antioxidants (melatonin and glutathione) modify these changes. Rats were exposed 8 hours/day for 26 or 52 days, with separate sham…
Effects of four kinds of electromagnetic fields (EMF) with different frequency spectrum bands on ovariectomized osteoporosis in mice.
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Jan 1, 2017
This animal study tested four frequency-band EMF exposures (1–50,000 Hz variants) in an ovariectomized mouse model of osteoporosis over 8 weeks (3 h/day). Low- and band-pass exposures increased bone formation markers and osteogenesis-related gene expression, while high-pass exposure decreased both formation and…
Efficacy of 50 Hz electromagnetic fields on human epidermal stem cell transplantation seeded in collagen sponge scaffolds for wound healing in a murine model.
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Jan 1, 2017
This animal study evaluated whether 50 Hz EMF exposure enhances wound healing after transplantation of human epidermal stem cells (ESC) seeded in collagen sponge scaffolds. Thirty-six nude mice with full-thickness wounds were assigned to control, ESC-only, or ESC+EMF groups (50 Hz, 5 mT, 60 min/day for 20 days). The…
The influence of prenatal 10 GHz microwave radiation exposure on a developing mice brain.
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Jan 1, 2017
This animal study examined prenatal exposure to 10 GHz microwave radiation starting at gestation day 0.25 or 11.25 until term. At 3 weeks of age, offspring from exposed pregnancies showed reduced brain and body weight and biochemical changes consistent with oxidative stress compared with sham controls. The authors…
Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats.
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Jan 1, 2017
This animal study examined whole-body exposure to 2.45 GHz microwave radiation for 2 h/day over 35 days in male Wistar rats. The authors report increased lipid peroxidation (LPO) in liver, brain, and spleen and histological changes across multiple organs compared with sham-exposed controls. They conclude the exposure…
Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation.
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Jan 1, 2017
This study investigated 2 nm protein-stabilized gold nanoclusters in six mammalian cell types under 1 GHz electromagnetic field exposure. The authors report low intrinsic toxicity of the nanoclusters, but a significant decrease in cell viability when nanocluster-incubated cells were exposed to the 1 GHz field,…