Immunohistochemical, Biochemical and Genetic Evaluation of the Effects of Ginseng Administration on Blood–Brain Barrier in Rats Exposed to 2100 MHz and 2450 MHz Electromagnetic Radiation
Research
RF Safe Research Library
Feb 27, 2026
This rat study examined effects of 2100 MHz and 2450 MHz EMF exposure on the bloodbrain barrier-related brain outcomes and whether ginseng modifies these effects. EMF exposure (1 h/day for 30 days) was reported to induce apoptosis in brain tissue, with decreased COX-2 gene expression and increased BAX protein.…
The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study
Research
PubMed: RF-EMF health
Jan 13, 2026
This PubMed-listed animal study reports results from the Japanese arm of an international Japan–Korea collaboration evaluating whether long-term mobile-phone-like RF-EMF exposure causes cancer or genetic damage in rats. Male Sprague Dawley rats were exposed to 900 MHz CDMA-modulated RF-EMF at a whole-body SAR of 4…
The effects of acute and chronic exposure of 3G UMTS 2100 MHz radiofrequency radiation on rat mismatch negativity
Research
RF Safe Research Library
Jan 1, 2026
This rat study examined acute (1-week) and chronic (10-week) exposure to 2100 MHz radiofrequency radiation (3G UMTS-like) and assessed auditory mismatch negativity (MMN) alongside biochemical and histological brain measures. The abstract reports that acute exposure was associated with reduced MMN-related…
Biological responses to 30 mT static magnetic field in young and 36-month-old rats
Research
RF Safe Research Library
Jan 1, 2026
This animal study examined subchronic exposure to a 30 mT static magnetic field for 10 weeks in young and 36-month-old rats (n=27). The abstract reports decreased lymphocyte counts and increased NLR in both age groups, with PLR increases limited to young rats and platelet decreases reported in older rats. The authors…
Mitigating Heat-Induced Sperm Damage and Testicular Tissue Abnormalities: The Protective Role of Radiofrequency Radiation from Wi-Fi Routers in Rodent Models
Research
PubMed: RF-EMF health
Dec 11, 2025
A rodent experimental study on PubMed reports that 2.45 GHz Wi‑Fi radiofrequency exposure may reduce heat stress–related damage in male rat testes and sperm parameters. The authors describe this as the first study examining a potentially protective effect of RF‑EMF against heat-induced testicular abnormalities,…
Alpha-Lipoic Acid Preserves Testicular Integrity Under 2.45 GHz Electromagnetic Radiation by Restoring Redox and Inflammatory Balance
Research
RF Safe Research Library
Jan 1, 2025
This animal study exposed adult male rats to 2.45 GHz electromagnetic radiation for 2 hours/day for one month and assessed testicular outcomes. The abstract reports that EMR exposure induced oxidative stress, increased inflammatory markers, and caused histological testicular injury. Alpha-lipoic acid supplementation…
Effects of non-ionizing radiation on the thyroid gland in rats
Research
RF Safe Research Library
Jan 1, 2025
This animal study exposed Sprague-Dawley rats (including pregnant females and offspring) to 2.45 GHz Wi-Fi or mobile jammer radiation for 2 hours daily over two weeks and assessed thyroid hormones and thyroid histology. The abstract reports significant changes in T4 in exposed adult males and significant differences…
The extremely low-frequency electromagnetic field (50 Hz) can establish a new "set-point" for the activity of the locus coeruleus-noradrenergic (LC-NA) system in rat.
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed rats to 50 Hz ELF-EMF at 1 mT or 7 mT for 1 hour/day over 7 days, repeated across three cycles, and assessed catecholamines, MHPG, β2-adrenergic receptor expression, and behavior. The authors report that ELF-EMF influences stress-response mechanisms involving the locus…
The Effect of Time-Dependence of 10 Hz Electromagnetic Field on Spatial Learning and Memory in Rats.
Research
RF Safe Research Library
Jan 1, 2022
This animal study exposed 40 adult male rats to a 10 Hz (4 mT) extremely low-frequency electromagnetic field for 1 hour daily for either 7 or 30 days. The authors report improved spatial memory after prolonged (30-day) exposure, alongside increased hippocampal BDNF levels. They also note a significant body weight…
Comparing the Effects of Long-term Exposure to Extremely Low-frequency Electromagnetic Fields With Different Values on Learning, Memory, Anxiety, and β-amyloid Deposition in Adult Rats.
Research
RF Safe Research Library
Jan 1, 2021
This animal study exposed adult male rats to 50 Hz ELF-EMF at 1, 100, 500, or 2000 μT for 1 hour/day over two months and assessed behavior and brain markers. The authors report increased memory retention (higher step-through latency) alongside increased anxiety-like behavior (reduced open-arm entries), particularly…
Electromagnetic Field Stimulation Attenuates Phasic Nociception after Complete Spinal Cord Injury in Rats.
Research
RF Safe Research Library
Jan 1, 2021
This animal study evaluated whole-body extremely low-frequency EMF stimulation after thoracic complete spinal cord injury in adult male rats. The authors report reduced nociceptive behaviors (hyperalgesia/allodynia) from week 6 onward and restoration of spinal reflexes by week 8. They also report lower glutamate at…
Effects induced by a 50 Hz electromagnetic field and doxorubicin on Walker-256 carcinosarcoma growth and hepatic redox state in rats.
Research
RF Safe Research Library
Jan 1, 2021
This animal study compared 50 Hz extremely low-frequency EMF exposure with doxorubicin (and their combination) in Walker-256 carcinosarcoma-bearing rats, assessing tumor growth and liver redox-related outcomes. DOX and DOX+EMF were reported to inhibit tumor growth more than EMF alone, though EMF alone also showed an…
Evaluation of the neuroprotective effects of Vitamin E on the rat substantia nigra neural cells exposed to electromagnetic field: An ultrastructural study.
Research
RF Safe Research Library
Jan 1, 2021
This rat study exposed animals to a 50 Hz, 3 mT electromagnetic field and assessed oxidative stress markers and substantia nigra ultrastructure. EMF exposure was associated with higher lipid peroxidation (MDA), lower SOD activity, and TEM-detected changes in nucleus/nuclear membrane and myelin sheath. Vitamin E…
Effect of Exposure to a Radiofrequency Electromagnetic Field on Body Temperature in Anesthetized and Non-Anesthetized Rats.
Research
RF Safe Research Library
Jan 1, 2020
This animal study examined whether anesthesia and body mass modify body temperature responses to 915 MHz RF exposure at 4 W/kg whole-body SAR for 8 hours. Non-anesthetized, free-moving rats showed no significant temperature change during exposure. In contrast, anesthetized rats showed marked temperature increases,…
Effects of extremely low-frequency electromagnetic field exposure on the skeletal muscle functions in rats.
Research
RF Safe Research Library
Jan 1, 2020
This rat study examined chronic extremely low-frequency electromagnetic field (ELF-EMF) exposure and diaphragm muscle function and structure. Rats were exposed to 50 Hz, 1.5 mT for 4 hours daily for up to 7 months and assessed with electrophysiological, biochemical, and electron-microscopy measures. The authors…
Electromagnetic Fields of Mobile Phone Jammer Exposure on Blood Factors in Rats.
Research
RF Safe Research Library
Jan 1, 2018
This rat study examined whether electromagnetic fields from a mobile phone jammer affect blood cell factors. Rats were exposed 8 hours/day, 5 days/week for 40 days and compared with control and sham groups. The authors report significant changes in multiple hematological indices, with some measures unchanged…
Effect of Microwave Wi-Fi Radiation at Frequency of 2.4 GHz on Epileptic Behavior of Rats.
Research
RF Safe Research Library
Jan 1, 2018
This animal study exposed rats to 2.4 GHz Wi-Fi radiation for 2 hours at 30 cm from a commercial router and assessed PTZ-induced convulsive behavior. The Wi-Fi "on" PTZ group showed significant differences in seizure event counts and summed severity scores versus comparison groups, while several timing and duration…
NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595
Research
RF Safe Research Library
Jan 1, 2018
This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…
No adverse effects detected for simultaneous whole-body exposure to multiple-frequency radiofrequency electromagnetic fields for rats in the intrauterine and pre- and post-weaning periods.
Research
RF Safe Research Library
Jan 1, 2017
This animal study exposed pregnant Sprague-Dawley rats and their offspring to simultaneous whole-body multifrequency RF signals spanning 800 MHz to 5.2 GHz. Exposure occurred 20 hours per day from gestational day 7 to weaning, with F1 offspring exposed up to 6 weeks of age. Across multiple endpoints including growth,…
Effects of extremely low frequency electromagnetic fields on morphine analgesia and tolerance in rats.
Research
RF Safe Research Library
Jan 1, 2017
This animal study examined whether extremely low frequency electromagnetic field exposure alters morphine analgesia and tolerance in rats. Rats exposed to a 50 Hz magnetic field (reported as 5 mT) showed higher morphine analgesic effects than rats given morphine without field exposure. In morphine-tolerant rats,…
Quantum mechanical model for the anticarcinogenic effect of extremely-low-frequency electromagnetic fields on early chemical hepatocarcinogenesis.
Research
RF Safe Research Library
Jan 1, 2017
This study develops a quantum-mechanical radical pair mechanism model to examine how an extremely-low-frequency electromagnetic field (ELF-EMF) might influence early chemical hepatocarcinogenesis in rats. The model evaluates singlet-state recombination and quantum yield under a low magnetic field effect, proposing…
The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil.
Research
RF Safe Research Library
Jan 1, 2017
This animal study examined combined exposure to microwave radiation and hypergravity in rats and assessed whether Rana sylvatica Le Conte oil had protective effects. The hypergravity plus microwave group showed reduced motor performance, reduced cholinergic enzyme activities, and reduced total antioxidant capacity,…
Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats
Research
RF Safe Research Library
Mar 19, 2015
This animal study exposed 108 male Sprague-Dawley rats to 900 MHz EMF (1 mW/cm2) or sham for 14 or 28 days (3 h/day). The authors report that 28-day exposure was associated with impaired spatial memory, BBB permeability damage, and ultrastructural changes in hippocampus and cortex. They also report increased mkp-1…
Impacts of exposure to 900 MHz mobile phone radiation on liver function in rats.
Research
RF Safe Research Library
Jan 1, 2015
This animal experiment randomized 20 male Sprague-Dawley rats to 900 MHz electromagnetic radiation exposure (4 h/day for 18 days) or no exposure. The exposed group showed increased oxidative stress markers in liver tissue (higher MDA, lower GSH) and reported histopathological changes, along with increased apoptosis…
Effects of extremely low-frequency electric fields at different intensities and exposure durations on mismatch negativity
Research
RF Safe Research Library
Jul 11, 2014
This rat study examined whether 50-Hz extremely low-frequency electric fields at 12 or 18 kV/m for 2 or 4 weeks affect mismatch negativity (MMN) and markers of oxidative damage/apoptosis in brain tissue. MMN amplitude was reported to be significantly reduced only in the 18 kV/m, 4-week exposure group versus the…