Low-energy amplitude-modulated electromagnetic field exposure: Feasibility study in patients with hepatocellular carcinoma.
Research
RF Safe Research Library
Jan 1, 2023
This single-site feasibility trial evaluated repeated 90-minute amplitude-modulated EMF exposure (AutEMdev) in 66 patients with advanced hepatocellular carcinoma. The primary focus was safety and hemodynamic variability during exposure, with exploratory outcomes including quality of life, survival, and tumor…
Safety and Efficacy of amplitude-modulated radiofrequency electromagnetic fields in advanced hepatocellular carcinoma
Research
RF Safe Research Library
Jan 1, 2021
This pooled case series evaluated amplitude-modulated 27.12 MHz RF EMF delivered via the TheraBionic P1 device (3 hours daily) in patients with advanced hepatocellular carcinoma, comparing outcomes to historical controls. The authors report longer median overall survival for Child-Pugh A patients versus comparable…
Hepatocellular carcinoma therapy finds a channel on the radio
Research
RF Safe Research Library
Jan 1, 2019
This EBioMedicine commentary discusses tumour-specific amplitude-modulated RF EMF as an anti-cancer therapy for hepatocellular carcinoma and highlights Cav3.2 (CACNA1H) T-type calcium channels as a proposed mediator of the effect. It notes that the reported whole-body averaged SAR in a treated HCC patient was below…
Liver lesion conspicuity during real-time MR-guided radiofrequency applicator placement using spoiled gradient echo and balanced steady-state free precession imaging.
Research
RF Safe Research Library
Jan 1, 2014
This retrospective study evaluated liver lesion conspicuity during real-time MR-guided radiofrequency applicator placement using spoiled GRE and balanced SSFP MRI sequences in a 1.5 T scanner. Lesion detectability categories and contrast-to-noise ratio (CNR) were compared for hepatocellular carcinoma and liver…
Comparison between different thickness umbrella-shaped expandable radiofrequency electrodes (SuperSlim and CoAccess): Experimental and clinical study.
Research
RF Safe Research Library
Jan 1, 2011
This experimental and clinical study compared two umbrella-shaped expandable radiofrequency ablation electrodes (SuperSlim vs CoAccess) across different ablation algorithms. In ex vivo bovine liver, CoAccess generally produced larger ablation areas and required longer ablation times than SuperSlim, with no…