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Filters: tag: extremely-low-frequency Clear

A Cohort Study on Alzheimer's Disease in Relation to Residential Magnetic Fields From Indoor Transformer Stations

Research RF Safe Research Library Jan 1, 2025

This cohort study evaluated Alzheimer's disease incidence in relation to residential extremely low frequency magnetic fields from indoor transformer stations, using apartment location as an exposure proxy. No significant association was observed between living next to transformer stations and Alzheimer's disease risk (HR 1.02, 95% CI 0.85–1.22). Duration of residence did not materially change risk, and a younger-start subgroup showed a non-significant elevation. The authors note the results did not replicate previously reported positive associations from other residential or occupational studies.

In situ electric field dosimetry analysis for powerline frequency peripheral nerve magnetic stimulation

Research RF Safe Research Library Jan 1, 2025

This study used computational dosimetry to analyze induced electric fields in a realistic human body model for a 60 Hz magnetic-field exposure system targeting the leg. Simulations indicated high EF intensities in several leg nerves and modeled conditions consistent with possible peripheral nerve stimulation. The MRG model produced lower stimulation thresholds than the SENN model, and nerve orientation was reported as a key determinant of stimulation risk.

Building the gulf of opinions on the health and biological effects of electromagnetic radiation

Research RF Safe Research Library Jan 1, 2025

This narrative article examines how opposing views formed regarding health and biological effects of electromagnetic radiation, focusing on ELF and RF exposures. It highlights historical controversies (e.g., childhood leukemia and ELF fields) and disputes over thermal versus non-thermal effects and reliance on SAR. The author argues that social and institutional factors, including industry influence, shaped interpretation and public discourse around EMF safety.

Human achromatic flickers and phosphenes thresholds under extremely low frequency electric stimulations

Research RF Safe Research Library Jan 1, 2025

This study estimated thresholds and locus for human phosphene perception during non-invasive transcranial alternating current stimulation at 20, 50, 60, and 100 Hz. Perception depended significantly on stimulation intensity, with the lowest threshold at 20 Hz and no reported phosphenes at 100 Hz. The authors report dosimetry consistent with a retinal origin and frame the findings as relevant for informing cautious ELF exposure limits in safety guidelines.

Exploring the influence of Schumann resonance and electromagnetic fields on bioelectricity and human health

Research RF Safe Research Library Jan 1, 2025

This review examines links between extremely low-frequency electromagnetic fields, especially the Schumann resonance at ~7.83 Hz, and biological regulation of bioelectricity. It describes proposed mechanisms involving calcium flux modulation and downstream effects on neural activity (including EEG) and circadian rhythms. The article presents both potential benefits from controlled ELF exposures (e.g., therapeutic applications) and potential harms from artificial EMFs disrupting key physiological processes, while emphasizing the need for further research.

Electromagnetic wireless remote control of mammalian transgene expression

Research RF Safe Research Library Jan 1, 2025

This animal proof-of-concept study describes an engineered nanoparticle–cell interface (EMPOWER) enabling wireless regulation of transgene expression using a 1-kHz magnetic field. Chitosan-coated multiferroic nanoparticles reportedly generate intracellular ROS that activates KEAP1/NRF2 biosensors connected to ROS-responsive promoters. In a mouse model of type 1 diabetes, implanted engineered cells expressing an EMPOWER-controlled insulin system reportedly normalized blood glucose in response to a weak magnetic field.

The Frequency of a Magnetic Field Determines the Behavior of Tumor and Non-Tumor Nerve Cell Models

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed glioblastoma (CT2A), neuroblastoma (N2A), and non-tumor astrocyte (C8D1A) cell models to a 100 μT magnetic field across 20–100 Hz for 24–72 hours. The abstract reports decreased viability and proliferation in the tumor cell models within a frequency window centered at 50 Hz, while astrocyte viability increased at 20 and 40 Hz. The authors conclude that frequency is a key determinant of cell-type-specific responses consistent with a “biological window” model.

Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects

Research RF Safe Research Library Jan 1, 2013

This narrative review argues that non-thermal biological effects of extremely low and microwave frequency EMFs may be mediated by activation of voltage-gated calcium channels (VGCCs). It cites 23 studies in which VGCC blockers reportedly block or reduce diverse EMF effects and proposes downstream Ca2+/calmodulin-dependent nitric oxide signaling. The review discusses both potential therapeutic effects (e.g., bone growth stimulation) and potential adverse effects via oxidative stress pathways, including a reviewed example of DNA single-strand breaks.

Biological effects of extremely low frequency electric and magnetic fields: a review

Research RF Safe Research Library Jan 1, 1977

This review summarizes reported biological effects of extremely low frequency (ELF) electric and magnetic fields, describing them as significant and often acting as stressors. Reported outcomes include metabolic, hormonal, and body weight changes in rodents, lethality at high exposure levels in mice and insects, and increased mitotic index in mouse tissues/cells under specified exposure conditions. The review suggests many effects may be mediated through neuroendocrine, nervous system, or behavioral responses to field exposure.

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